LV10911B - Stabilized medicinal aerosol solution formulations - Google Patents

Stabilized medicinal aerosol solution formulations Download PDF

Info

Publication number
LV10911B
LV10911B LVP-95-163A LV950163A LV10911B LV 10911 B LV10911 B LV 10911B LV 950163 A LV950163 A LV 950163A LV 10911 B LV10911 B LV 10911B
Authority
LV
Latvia
Prior art keywords
acid
pharmaceutical composition
liquid pharmaceutical
composition according
hfc
Prior art date
Application number
LVP-95-163A
Other languages
English (en)
Latvian (lv)
Other versions
LV10911A (lv
Inventor
Jager Paul Donald
Kontny Mark James
Nagel J Rgen
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26850651&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV10911(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of LV10911A publication Critical patent/LV10911A/xx
Publication of LV10911B publication Critical patent/LV10911B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
LVP-95-163A 1992-12-09 1995-06-09 Stabilized medicinal aerosol solution formulations LV10911B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98785292A 1992-12-09 1992-12-09
US15354993A 1993-11-22 1993-11-22

Publications (2)

Publication Number Publication Date
LV10911A LV10911A (lv) 1995-12-20
LV10911B true LV10911B (en) 1996-04-20

Family

ID=26850651

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-163A LV10911B (en) 1992-12-09 1995-06-09 Stabilized medicinal aerosol solution formulations

Country Status (28)

Country Link
US (3) US5676930A (xx)
EP (1) EP0673240B1 (xx)
JP (1) JP3009924B2 (xx)
KR (1) KR100312357B1 (xx)
AT (1) ATE177941T1 (xx)
AU (2) AU6048694A (xx)
BG (1) BG62382B1 (xx)
BR (1) BR9307627A (xx)
CA (1) CA2151383C (xx)
CZ (1) CZ284203B6 (xx)
DE (1) DE69324161T2 (xx)
DK (1) DK0673240T3 (xx)
ES (1) ES2129117T3 (xx)
FI (1) FI114283B (xx)
GB (1) GB2288978B (xx)
GR (1) GR3030529T3 (xx)
HK (1) HK1011620A1 (xx)
HU (1) HU221163B1 (xx)
LV (1) LV10911B (xx)
NO (1) NO311487B1 (xx)
NZ (1) NZ259192A (xx)
PL (1) PL177078B1 (xx)
RO (1) RO117414B1 (xx)
RU (1) RU2126248C1 (xx)
SG (1) SG52459A1 (xx)
SK (1) SK280911B6 (xx)
UA (1) UA27143C2 (xx)
WO (2) WO1994013262A1 (xx)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA27143C2 (uk) * 1992-12-09 2000-02-28 Берінгер Інгельхейм Фармасьютікалс Інк Рідка фармацевтичhа композиція в формі аерозолю
AU4655596A (en) * 1995-01-17 1996-08-07 Omega Pharmaceutical, Incorporated Liquid stable vitamin c compositions and delivery systems, and methods of making and uses thereof
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
CA2217950C (en) * 1995-04-14 2001-12-25 Glaxo Wellcome Inc. Metered dose inhaler for albuterol
EP0835098B1 (de) 1995-06-27 2002-09-04 Boehringer Ingelheim Pharma KG Neue stabile arzneimittelzubereitung zur erzeugung treibgasfreier aerosole
DE19528145A1 (de) * 1995-08-01 1997-02-06 Boehringer Ingelheim Kg Neue Arzneimittel und ihre Verwendung
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US20030215396A1 (en) 1999-09-15 2003-11-20 Boehringer Ingelheim Pharma Kg Method for the production of propellant gas-free aerosols from aqueous medicament preparations
CA2275889C (en) 1996-12-30 2008-03-18 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
CZ296966B6 (cs) * 1997-02-24 2006-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Farmaceutický prostredek
GB2326334A (en) * 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
AU3065999A (en) * 1998-03-10 1999-09-27 Children's Hospital Of Philadelphia, The Compositions and methods for treatment of asthma
PT1087750E (pt) * 1998-06-18 2004-02-27 Boehringer Ingelheim Pharma Formulacoes farmaceuticas para aerossois com duas ou mais substancias activas
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
GB9902689D0 (en) * 1999-02-08 1999-03-31 Novartis Ag Organic compounds
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
US20040002548A1 (en) * 1999-05-12 2004-01-01 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
US20100197719A1 (en) * 1999-05-12 2010-08-05 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
DE60031504T2 (de) 1999-09-11 2007-04-05 Glaxo Group Ltd., Greenford Fluticasonpropionat arzneizubereitung
WO2001047493A1 (en) * 1999-12-24 2001-07-05 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
CA2411047C (en) 2000-05-22 2009-08-04 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
ATE276253T1 (de) * 2000-10-12 2004-10-15 Boehringer Ingelheim Pharma Kristallines monohydrat von tiotropiumbromid, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels
US6908928B2 (en) 2000-10-12 2005-06-21 Bi Pharma Kg. Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
US6620438B2 (en) * 2001-03-08 2003-09-16 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists
DE10063957A1 (de) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20020085978A1 (en) * 2000-11-10 2002-07-04 Mina Buenafe Degradation-resistant glucocorticosteroid formulations
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
DE10111843A1 (de) * 2001-03-13 2002-09-19 Boehringer Ingelheim Pharma Verbindungen zur Behandlung von inflammatorischen Erkrankungen
US6455028B1 (en) 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
AU2002303425A1 (en) * 2001-04-24 2002-11-05 Epigenesis Pharmaceuticals, Inc. Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent
SI1273292T1 (en) 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
DE10135355C1 (de) * 2001-07-20 2003-04-17 Schering Ag Konjugate makrocyclischer Metallkomplexe mit Biomolekülen und deren Verwendung zur Herstellung von Mitteln für die NMR- und Radiodiagnostik sowie die Radiotherapie
CN1290502C (zh) 2001-09-18 2006-12-20 丹麦奈科明有限公司 治疗普通感冒的组合物
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
WO2003037317A1 (en) * 2001-10-26 2003-05-08 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
AU3297402A (en) * 2001-10-26 2003-10-30 Dey, L.P. An albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US8084461B2 (en) 2001-10-26 2011-12-27 Dey, L.P. Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
DE10161368A1 (de) * 2001-12-14 2003-07-10 Messer Griesheim Gmbh Vorrichtung und Verfahren zum kryogenen Abfüllen von Aerosol-Produktansätzen
JP4959919B2 (ja) 2001-12-21 2012-06-27 スリーエム イノベイティブ プロパティズ カンパニー 官能基を有するポリエチレングリコール賦形剤を用いた医薬用エアロゾル組成物
JP2005514440A (ja) 2001-12-21 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー アミドおよび／またはエステルを含有する、賦形剤化合物を含む、医用エアロゾル組成物
US20030147814A1 (en) * 2001-12-21 2003-08-07 3M Innovative Properties Company Medicinal aerosol formulations comprising ion pair complexes
IL163843A0 (en) * 2002-03-01 2005-12-18 Chiesi Farma Spa Formoterol superfine formulation
US20040126325A1 (en) * 2002-03-12 2004-07-01 David Lewis Medicinal aerosol solution formulation products with improved chemical stability
US7244415B2 (en) 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US7311894B2 (en) * 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
US7238661B2 (en) * 2002-05-24 2007-07-03 Agennix, Inc. Oral lactoferrin in the treatment of respiratory disorders
CA2487399A1 (en) * 2002-06-12 2004-02-19 Epigenesis Pharmaceuticals, Inc. Combination of anti-muscarinic agents and non-glucocorticoid steroids
US7056916B2 (en) * 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
WO2004054580A1 (en) * 2002-12-16 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing hfc solution formulations
US20050058606A1 (en) * 2002-12-16 2005-03-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing HFC solution formulations
SI1608336T1 (sl) * 2003-03-20 2008-08-31 Boehringer Ingelheim Pharma Formulacija za dozirni inhalator, kjer se uporabljajo hidrofluoroalkani kot poganjalna sredstva
EP1915985A1 (en) * 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulation for a Metered Dose Inhaler Using Hydro-Fluoro-Alkanes as Propellants
US7273603B2 (en) 2003-07-11 2007-09-25 Boehringer Ingelheim International Gmbh HFC solution formulations containing an anticholinergic
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
US20050038004A1 (en) * 2003-07-31 2005-02-17 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050101545A1 (en) * 2003-07-31 2005-05-12 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
IL177103A0 (en) * 2004-02-27 2006-12-10 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurized metered dose inhalers
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
KR101297061B1 (ko) * 2004-07-02 2013-08-19 베링거 인겔하임 인터내셔날 게엠베하 추진제로서 ｔｇ ２２７ ｅａ 또는 ｔｇ １３４ ａ를함유하는 에어로졸 현탁액 제형
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
CN101119706B (zh) * 2005-02-25 2013-04-17 奇斯药制品公司 用于加压计量吸入器的包含螯合剂的药物气雾制剂
EP1879571A1 (de) * 2005-04-23 2008-01-23 Boehringer Ingelheim International GmbH Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid
WO2006117299A2 (en) 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
US20070088160A1 (en) * 2005-08-15 2007-04-19 Thomas Krueger Process for the manufacturing of betamimetics
RU2457832C2 (ru) * 2005-09-25 2012-08-10 Сипла Лимитед Состав на основе тровентола
US20070088030A1 (en) * 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
TWI396541B (zh) * 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
DE102006023770A1 (de) * 2006-05-20 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Treibgasfreie Aerosolformulierung für die Inhalation
WO2008008494A2 (en) * 2006-07-13 2008-01-17 Accentia Biopharmaceuticals, Inc. Methods and compositions for treating mucosal inflammation
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2201934A1 (en) 2008-12-23 2010-06-30 CHIESI FARMACEUTICI S.p.A. Tiotropium aerosol formulation products with improved chemical stability
JP5670421B2 (ja) 2009-03-31 2015-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング コンポーネント表面のコーティング方法
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
NZ600208A (en) 2009-11-17 2014-06-27 Cipla Ltd Inhalation solutions
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064164A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
WO2011084316A2 (en) 2009-12-16 2011-07-14 3M Innovative Properties Company Formulations and methods for controlling mdi particle size delivery
GEP20166479B (en) 2009-12-23 2016-05-25 Chiesi Farma Spa Aerosol formulation for copd
CN104055765B (zh) * 2009-12-23 2016-11-23 奇斯药制品公司 用于copd的联合治疗
JP5874724B2 (ja) 2010-06-24 2016-03-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
JP5409594B2 (ja) * 2010-12-22 2014-02-05 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧式定量吸入器のための安定な製薬学的溶液製剤
US20120204871A1 (en) 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
GB201200504D0 (en) 2011-12-19 2012-02-22 Teva Branded Pharmaceutical Prod R & D Inc An inhaler
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
JP6335798B2 (ja) * 2012-02-28 2018-05-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規噴射剤含有チオトロピウム製剤
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
RU2496477C1 (ru) * 2012-09-20 2013-10-27 Шолекс Девелопмент Гмбх Раствор ипратропия бромида
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
RU2536253C1 (ru) * 2013-10-09 2014-12-20 Шолекс Девелопмент Гмбх Комбинированный аэрозольный препарат для лечения болезней органов дыхания
EP2897589B1 (en) 2013-11-22 2018-01-03 Teva Branded Pharmaceutical Products R & D, Inc. An inhalable medicament
PL2897588T3 (pl) * 2013-11-22 2019-12-31 Teva Branded Pharmaceutical Products R&D, Inc. Lek wziewny
KR102443737B1 (ko) 2014-05-07 2022-09-19 베링거 인겔하임 인터내셔날 게엠베하 컨테이너, 분무기 및 사용 방법
KR20230018542A (ko) 2014-05-07 2023-02-07 베링거 인겔하임 인터내셔날 게엠베하 분무기, 표시 디바이스 및 컨테이너
EP3139984B1 (en) 2014-05-07 2021-04-28 Boehringer Ingelheim International GmbH Nebulizer
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
RU2577289C1 (ru) * 2015-03-26 2016-03-10 Шолекс Девелопмент Гмбх Аэрозольный препарат на основе фенотерола гидробромида для лечения заболеваний органов дыхания
EP3922240B1 (en) * 2016-09-19 2023-06-21 Mexichem Fluor S.A. de C.V. Pharmaceutical composition comprising tiotropium bromide
EP3569221A1 (en) * 2018-05-17 2019-11-20 Notoxins IP B.V. Aqueous formulations comprising ipratropium for topical treatment of hyperhidrosis
WO2020152548A1 (en) * 2019-01-24 2020-07-30 Glenmark Pharmaceuticals Limited Stable aerosol inhalation compositions of formoterol
GB2584686A (en) * 2019-06-11 2020-12-16 Mexichem Fluor Sa De Cv Methods
CN111297835B (zh) * 2019-12-20 2022-11-25 上海方予健康医药科技有限公司 含抗胆碱能药物的吸入气雾剂及其制备工艺和使用方法
US20230277451A1 (en) * 2020-10-09 2023-09-07 Chiesi Farmaceutici S.P.A. A pharmaceutical formulation for pressurised metered dose inhaler

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE555319A (xx) * 1956-03-21 1900-01-01
US3282781A (en) * 1960-11-25 1966-11-01 Merck & Co Inc Inhalant compositions
ZA815698B (en) * 1980-08-28 1983-04-27 Lilly Co Eli Intranasal formulation
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8900267D0 (en) * 1989-01-06 1989-03-08 Riker Laboratories Inc Narcotic analgesic formulations and apparatus containing same
US5439670A (en) * 1989-11-28 1995-08-08 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
DE4003272A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
ES2084360T3 (es) * 1991-06-10 1996-05-01 Schering Corp Formulaciones de aerosoles exentas de clorofluorocarbonos.
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
UA27143C2 (uk) * 1992-12-09 2000-02-28 Берінгер Інгельхейм Фармасьютікалс Інк Рідка фармацевтичhа композиція в формі аерозолю
US5837699A (en) * 1994-01-27 1998-11-17 Schering Corporation Use of mometasone furoate for treating upper airway passage diseases

Also Published As

Publication number Publication date
HU221163B1 (en) 2002-08-28
KR950703932A (ko) 1995-11-17
WO1994013262A1 (en) 1994-06-23
CZ149095A3 (en) 1995-12-13
GB9511669D0 (en) 1995-08-23
SG52459A1 (en) 1998-09-28
US5955058A (en) 1999-09-21
GB2288978B (en) 1997-04-09
AU5740594A (en) 1994-07-04
BG62382B1 (bg) 1999-10-29
DK0673240T3 (da) 1999-10-11
AU6048694A (en) 1994-07-04
WO1994013263A1 (en) 1994-06-23
JPH08509459A (ja) 1996-10-08
RU2126248C1 (ru) 1999-02-20
BR9307627A (pt) 1999-06-15
ES2129117T3 (es) 1999-06-01
CA2151383C (en) 2005-02-08
RO117414B1 (ro) 2002-03-29
PL177078B1 (pl) 1999-09-30
NZ259192A (en) 1997-05-26
FI952842A0 (fi) 1995-06-09
JP3009924B2 (ja) 2000-02-14
ATE177941T1 (de) 1999-04-15
FI114283B (fi) 2004-09-30
NO952269L (no) 1995-06-08
GB2288978A (en) 1995-11-08
HK1011620A1 (en) 1999-07-16
AU680227B2 (en) 1997-07-24
DE69324161D1 (de) 1999-04-29
NO311487B1 (no) 2001-12-03
US5676930A (en) 1997-10-14
HU9501663D0 (en) 1995-08-28
KR100312357B1 (ko) 2002-04-24
DE69324161T2 (de) 1999-10-28
US6045778A (en) 2000-04-04
NO952269D0 (no) 1995-06-08
BG99760A (bg) 1996-02-28
UA27143C2 (uk) 2000-02-28
CA2151383A1 (en) 1994-06-23
HUT72985A (en) 1996-06-28
PL309333A1 (en) 1995-10-02
LV10911A (lv) 1995-12-20
EP0673240A1 (en) 1995-09-27
SK76095A3 (en) 1997-01-08
SK280911B6 (sk) 2000-09-12
GR3030529T3 (en) 1999-10-29
FI952842A (fi) 1995-06-09
CZ284203B6 (cs) 1998-09-16
EP0673240B1 (en) 1999-03-24

Similar Documents

Publication Publication Date Title
US5955058A (en) Stabilized medicinal aerosol solution formulations containing ipratropium bromide
EP1646364B1 (en) Hfc solution formulations containing an anticholinergic
US5605674A (en) Medicinal aerosol formulations
EP0499344B1 (en) Medicinal aerosol formulations
US20090175802A1 (en) Tiotropium containing hfc solution formulations
KR20050085650A (ko) 타이오트로피움 함유 ｈｆｃ 용액 제형
CN1054282C (zh) 稳定的药物气雾剂溶液制剂
CA2303601A1 (en) Medicinal aerosol formulations