LU90208I2 - Pramipexole et ses sels dichlorhydrate monohydraté de pramipexole - Google Patents

Pramipexole et ses sels dichlorhydrate monohydraté de pramipexole

Info

Publication number
LU90208I2
LU90208I2 LU90208C LU90208C LU90208I2 LU 90208 I2 LU90208 I2 LU 90208I2 LU 90208 C LU90208 C LU 90208C LU 90208 C LU90208 C LU 90208C LU 90208 I2 LU90208 I2 LU 90208I2
Authority
LU
Luxembourg
Prior art keywords
group
phenyl
alkyl
hydrogen atom
pramipexole
Prior art date
Application number
LU90208C
Other languages
English (en)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25827684&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90208(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19843447075 external-priority patent/DE3447075A1/de
Priority claimed from DE19853508947 external-priority patent/DE3508947A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of LU90208I2 publication Critical patent/LU90208I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Cereal-Derived Products (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LU90208C 1984-12-22 1998-01-30 Pramipexole et ses sels dichlorhydrate monohydraté de pramipexole LU90208I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843447075 DE3447075A1 (de) 1984-12-22 1984-12-22 Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel
DE19853508947 DE3508947A1 (de) 1985-03-13 1985-03-13 Mittel zur behandlung des parkinsonismus bzw. der parkinsonschen-erkrankung

Publications (1)

Publication Number Publication Date
LU90208I2 true LU90208I2 (fr) 1998-04-06

Family

ID=25827684

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90208C LU90208I2 (fr) 1984-12-22 1998-01-30 Pramipexole et ses sels dichlorhydrate monohydraté de pramipexole

Country Status (25)

Country Link
US (3) US4731374A (fr)
EP (1) EP0186087B1 (fr)
KR (1) KR930009791B1 (fr)
AT (1) ATE45735T1 (fr)
AU (1) AU583874B2 (fr)
BG (1) BG62023B2 (fr)
CA (1) CA1263653A (fr)
CS (1) CS409991A3 (fr)
DE (1) DE3572485D1 (fr)
DK (1) DK168862B1 (fr)
ES (5) ES8702787A1 (fr)
FI (1) FI81787C (fr)
GR (1) GR853126B (fr)
HK (1) HK78692A (fr)
HU (1) HU193618B (fr)
IE (1) IE58863B1 (fr)
IL (1) IL77415A (fr)
LU (1) LU90208I2 (fr)
MX (1) MX9202792A (fr)
NL (1) NL980002I2 (fr)
NO (1) NO165070C (fr)
NZ (1) NZ214661A (fr)
PH (1) PH24533A (fr)
PT (1) PT81735B (fr)
SG (1) SG82492G (fr)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3620813A1 (de) * 1986-06-21 1987-12-23 Boehringer Ingelheim Kg Neue tetrahydro-benzothiazole, ihre herstellung und verwendung
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
US4988699A (en) * 1989-03-14 1991-01-29 Warner-Lambert Company Substituted tetrahydrobenzothiazoles as dopaminergic agents
DE3923689A1 (de) * 1989-07-18 1991-01-24 Boehringer Ingelheim Kg Neue verwendung von tetrahydrobenzthiazolderivaten als arzneistoffe
DE3930282A1 (de) * 1989-09-11 1991-03-21 Boehringer Ingelheim Kg Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit
DE3937271A1 (de) * 1989-11-09 1991-05-16 Boehringer Ingelheim Kg Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol
FR2674853B1 (fr) * 1991-04-03 1995-01-20 Synthelabo Derives de piperidinylguanidine, leur preparation et leur application en therapeutique.
DE4241013A1 (de) * 1992-12-05 1994-06-09 Boehringer Ingelheim Kg Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung
US5650420A (en) * 1994-12-15 1997-07-22 Pharmacia & Upjohn Company Pramipexole as a neuroprotective agent
US6156777A (en) * 1994-12-15 2000-12-05 Pharmacia & Upjohn Company Use of pramipexole as a neuroprotective agent
DE19507752A1 (de) * 1995-03-06 1996-09-12 Bayer Ag Verfahren zur Herstellung von substituierten Cyclohexanonen
DE19536916A1 (de) * 1995-10-04 1997-04-10 Boehringer Ingelheim Kg Inhalative Applikation von 2-Amino-6n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol, insbesondere seines (-)-Enantiomeren, sowie deren pharmakologisch verträgliche Säureadditionssalze
CA2255612A1 (fr) * 1996-05-31 1997-12-04 Pharmacia & Upjohn Company Amines cycliques a substitution aryle utilisees comme ligands de la dopamine d3
US6001861A (en) * 1998-01-16 1999-12-14 Pharmacia & Upjohn Company Use of pramipexole in the treatment of restless legs syndrome
DE19701619B4 (de) * 1997-01-17 2007-10-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Pramipexol zur Behandlung des restless legs syndroms
AU760439B2 (en) * 1998-05-15 2003-05-15 Pharmacia & Upjohn Company Cabergoline and pramipexole: new uses and combinations
SE9802360D0 (sv) * 1998-07-01 1998-07-01 Wikstroem Hakan Vilhelm New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin
DE19830201A1 (de) * 1998-07-07 2000-01-13 Boehringer Ingelheim Pharma Mittel mit antidepressiver Wirkung
US6232326B1 (en) 1998-07-14 2001-05-15 Jodi A. Nelson Treatment for schizophrenia and other dopamine system dysfunctions
PE20011074A1 (es) 2000-02-23 2001-10-04 Upjohn Co Uso de pramipexol en el tratamiento de trastornos de adiccion
AU7887501A (en) * 2000-07-06 2002-01-21 Us Gov Health & Human Serv Tetrahydrobenzothiazole analogues as neuroprotective agents
US6277875B1 (en) * 2000-07-17 2001-08-21 Andrew J. Holman Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
ES2187249B1 (es) * 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
US20020165246A1 (en) * 2001-03-05 2002-11-07 Andrew Holman Administration of sleep restorative agents
DE10137453A1 (de) * 2001-08-02 2003-02-20 Boehringer Ingelheim Pharma Pramlpexol als Antikonvulsivum
DE10138275A1 (de) * 2001-08-10 2003-02-27 Boehringer Ingelheim Pharma Verbindungen zur Beseitigung der Anhedonie
US20060281797A1 (en) * 2001-12-11 2006-12-14 University Of Virginia Patent Foundation Neurorestoration with R(+) Pramipexole
AU2002360600B2 (en) 2001-12-11 2007-11-29 University Of Virginia Patent Foundation Use of pramipexole to treat amyotrophic lateral sclerosis
US20030166696A1 (en) * 2002-01-24 2003-09-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pramipexole for the treatment of HIV dementia
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
US20050226926A1 (en) * 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
US20070196481A1 (en) * 2002-07-25 2007-08-23 Amidon Gregory E Sustained-release tablet composition
PE20040134A1 (es) * 2002-07-25 2004-03-06 Pharmacia Corp Forma de dosificacion de una vez al dia de pramipexol
GB0221513D0 (en) * 2002-09-17 2002-10-23 Generics Uk Ltd Novel compounds and processes
GB2394951A (en) * 2002-11-04 2004-05-12 Cipla Ltd One pot synthesis of 2,6-diamino-4,5,6,7-tetrahydro-benzothiazole
US7365086B2 (en) * 2003-07-25 2008-04-29 Synthon Ip Inc. Pramipexole acid addition salts
DE102004006808A1 (de) * 2004-02-11 2005-09-01 Grünenthal GmbH Substituierte 4,5,6,7-Tetrahydro-benzothiazol-2-ylamin-Verbindungen
EP1730129B1 (fr) 2004-03-19 2011-01-19 Dipharma Francis S.r.l. Intermediaires pour la preparation de pramipexole
ES2245604B1 (es) 2004-06-25 2006-12-01 Ragactives, S. L. Procedimiento para la obtencion de 2-amino-6-alquil-amino-4,5,6,7-tetrahidrobenzotiazoles.
WO2006012276A1 (fr) * 2004-06-30 2006-02-02 Amr Technology, Inc. Processus pour préparer des 2-amino-6-(alkyl)amino-4,5,6,7-tétrahydrobenzothiazoles chiralement purs par résolution chromatographique en phase liquide
CA2553311A1 (fr) * 2004-07-01 2006-01-12 Alembic Limited Procede ameliore de preparation d'un derive de tetrahydrobenzothiazole biologiquement actif
WO2006003471A2 (fr) * 2004-07-03 2006-01-12 Generics [Uk] Limited Nouveau procede
EP1778201B1 (fr) * 2004-08-13 2014-07-16 Boehringer Ingelheim International GmbH Compositions pharmaceutiques sous forme de granulés contenant du pramipexole ou l'un de ses sels , leur procédé de préparation et leur utilisation
PL1789021T3 (pl) 2004-08-13 2012-04-30 Boehringer Ingelheim Int Preparat tabletkowy o przedłużonym uwalnianiu zawierający pramipeksol lub jego farmaceutycznie dopuszczalną sól
CA2579279C (fr) * 2004-10-07 2013-10-01 Boehringer Ingelheim International Gmbh Derives de thiazole tricyclique en tant que pi3-kinases
WO2006070349A2 (fr) * 2004-12-30 2006-07-06 Chemagis Ltd. Nouveau procede destine a preparer du pramipexole et son melange isomerique optique par reduction avec du triacetoxyborohydride de sodium
CN1834092B (zh) * 2005-03-15 2010-04-28 姜能桥 盐酸普拉克索的制备方法
US20090062549A1 (en) * 2005-05-03 2009-03-05 Seema Kanwar Process for the preparation of pramipexole and new anhydrous forms of its dihydrochloride
ES2264378B1 (es) * 2005-05-09 2007-11-01 Ragactives, S.L. Procedimiento para la resolucion de 2-amino-6propilamino-4,5,6,7-tetrahidrobenzotiazol y compuestos intermedios.
EP1731514A1 (fr) * 2005-06-02 2006-12-13 Sandoz AG Méthode de préparation du pramipexole
JP2009504748A (ja) * 2005-08-15 2009-02-05 ユニバーシティ オブ バージニア パテント ファウンデーション Ｒ（＋）プラミペキソールを用いた神経回復
US7994220B2 (en) 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
EP1940398A1 (fr) * 2005-10-18 2008-07-09 Boehringer Ingelheim International GmbH Utilisation de pramipexol pour traiter le syndrome des jambes sans repos (rls) modere a severe
JP2009517460A (ja) * 2005-12-02 2009-04-30 アレムビック・リミテッド プラミペキソールの安定化医薬組成物およびその製造方法
PL378587A1 (pl) * 2005-12-29 2007-07-09 Instytut Farmaceutyczny Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli
ITMI20060044A1 (it) * 2006-01-13 2007-07-14 Dipharma Spa Sintesi di intermedi pr la preparazione di pramipexolo
US20090041844A1 (en) * 2006-02-10 2009-02-12 Boehringer Ingelheim International Gmbh Modified Release Formulation
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
US20070259930A1 (en) * 2006-04-10 2007-11-08 Knopp Neurosciences, Inc. Compositions and methods of using r(+) pramipexole
EP2497472A1 (fr) 2006-05-16 2012-09-12 Knopp Neurosciences, Inc. Quantités thérapeutiquement efficaces de R(+) et S(-) pramipexole pour une utilisation dans le traitement de la maladie de Parkinson et leurs compositions pharmaceutiques
CN101448498B (zh) 2006-05-16 2011-04-27 诺普神经科学股份有限公司 R(+)和s(-)普拉克索的组合物以及使用该组合物的方法
EP2026766A1 (fr) 2006-05-17 2009-02-25 Synthon B.V. Composition en comprimé pour la libération prolongée de la tamsulosine
WO2008001200A2 (fr) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Composition transdermique à stabilité de couleur améliorée
US20080254118A1 (en) * 2007-04-11 2008-10-16 Hans-Werner Wernersbach Process for preparing pramipexole dihydrochloride tablets
WO2008041240A1 (fr) * 2006-10-03 2008-04-10 Cadila Healthcare Limited Procédé de préparation de (s)-pramipexole et de ses intermédiaires
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
WO2008086353A1 (fr) * 2007-01-08 2008-07-17 Zurawski Vincent R Jr Dérivés contenant du propargyle de tétrahydro-benzthiazoles et procédés de fabrication et d'utilisation de ceux-ci
SI22446A (sl) * 2007-02-07 2008-08-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek za sintezo pramipeksola in njegovih farmacevtsko sprejemljivih soli
US8519148B2 (en) 2007-03-14 2013-08-27 Knopp Neurosciences, Inc. Synthesis of chirally purified substituted benzothiazole diamines
US20080254117A1 (en) * 2007-04-10 2008-10-16 Noel Cotton Process for preparing pramipexole dihydrochloride tablets
SI2185198T1 (sl) 2007-08-02 2015-04-30 Gilead Biologics, Inc. Inhibitorji LOX in LOXL2 ter njihova uporaba
GB0721333D0 (en) * 2007-10-31 2007-12-12 Motac Neuroscience Ltd Medicaments
US20090247537A1 (en) * 2008-03-25 2009-10-01 William Dale Overfield Methods for preventing or treating bruxism using dopaminergic agents
WO2010022140A1 (fr) * 2008-08-19 2010-02-25 Knopp Neurosciences, Inc. Compositions et procédés employant du (r)-pramipexole
US9107935B2 (en) 2009-01-06 2015-08-18 Gilead Biologics, Inc. Chemotherapeutic methods and compositions
WO2010148409A1 (fr) * 2009-06-19 2010-12-23 Knopp Neurosciences, Inc. Compositions et méthodes pour traiter la sclérose latérale amyotrophique (als)
US20110207144A1 (en) * 2009-08-21 2011-08-25 Derek Marshall In vitro screening assays
US20110044907A1 (en) * 2009-08-21 2011-02-24 Derek Marshall In vivo screening assays
EP2467169A4 (fr) * 2009-08-21 2013-01-02 Gilead Biologics Inc Essais de criblage in vivo
AU2010284036B2 (en) 2009-08-21 2014-12-18 Gilead Biologics, Inc. Catalytic domains from lysyl oxidase and LOXL2
KR20120054076A (ko) * 2009-08-21 2012-05-29 길리아드 바이오로직스, 인크. 치료적 방법 및 조성물
TR200906997A1 (tr) 2009-09-11 2011-03-21 Sanovel �La� San. Ve T�C. A. �. Pramipeksol farmasötik bileşimleri.
TR200907554A1 (tr) 2009-10-06 2011-04-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Oral yolla dağılan pramıpexole bileşimleri.
EP2525786A2 (fr) 2010-01-18 2012-11-28 Synthon BV Comprimés à libération prolongée de pramipexole
JP6134142B2 (ja) 2010-02-04 2017-05-24 ギリアド バイオロジクス, インク.Gilead Biologics, Inc. リシルオキシダーゼ様２（ｌｏｘｌ２）に結合する抗体及びその使用方法
US20130079526A1 (en) 2010-03-03 2013-03-28 Knopp Neurosciences Inc. Synthesis of Chirally Purified Substituted Benzothiazole Diamines
TR201001862A1 (tr) * 2010-03-11 2011-10-21 Sanovel �La� San.Ve T�C.A.�. Kontrollü salım gerçekleştiren pramipeksol formülasyonları.
EP2575780A1 (fr) 2010-05-24 2013-04-10 Lupin Limited Formulation à libération prolongée de pramipexole
EP2462925A1 (fr) 2010-11-12 2012-06-13 Neuraxpharm Arzneimittel GmbH Granulé de dihydrochlorure de pramipexole
TWI537274B (zh) 2011-03-14 2016-06-11 橘生藥品工業股份有限公司 新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途
WO2012140604A1 (fr) 2011-04-15 2012-10-18 Sandoz Ag Formulations stables de chlorhydrate de pramipexole
ITMI20110666A1 (it) * 2011-04-19 2012-10-20 Dipharma Francis Srl Procedimento per la preparazione di (r) ed (s) pramipexolo e suoi intermedi
WO2013096816A1 (fr) 2011-12-22 2013-06-27 Biogen Idec Ma Inc. Synthèse améliorée de composés substitués par amine de 4,5,6,7-tétrahydrobenzothiazole
EP2732812A1 (fr) 2012-11-15 2014-05-21 Aristo Pharma GmbH Comprimé de pramipexol à libération prolongée
JP6242811B2 (ja) 2012-12-10 2017-12-06 キッセイ薬品工業株式会社 新規なオクタヒドロピリドキナゾリン誘導体、それを含有する医薬組成物およびそれらの用途
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
LT3019167T (lt) 2013-07-12 2021-03-25 Knopp Biosciences Llc Eozinofilų ir (arba) bazofilų padidintų kiekių gydymas
CA2921381A1 (fr) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions et methodes pour le traitement de l'urticaire chronique
EP3038467B1 (fr) 2013-08-13 2020-07-29 Knopp Biosciences LLC Compositions et méthodes de traitement de troubles des cellules plasmatiques et de troubles prolymphocytaires à cellules b
EP2870965A1 (fr) 2013-11-06 2015-05-13 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations pharmaceutiques liquides orales de pramipexole
EP2870961B1 (fr) 2013-11-06 2018-07-18 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations effervescentes de pramipexole
CN103626718A (zh) * 2013-12-13 2014-03-12 山东新华制药股份有限公司 盐酸普拉克索的工业化制备方法
CN103664820B (zh) * 2013-12-30 2016-01-27 四川科伦药业股份有限公司 普拉克索类似物及其制备方法
AU2017281789B2 (en) 2016-06-23 2023-04-13 Corium, LLC. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
SG11201900712SA (en) 2016-07-27 2019-02-27 Corium Int Inc Memantine transdermal delivery systems
US10016372B2 (en) 2016-07-27 2018-07-10 Corium International, Inc. Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery
EP3490558A1 (fr) 2016-07-27 2019-06-05 Corium International, Inc. Système d'administration transdermique de donépézil
EP3609495B1 (fr) 2017-04-10 2024-07-24 Chase Therapeutics Corporation Association comprenant un antagoniste de nk1 et méthode de traitement de synucléinopathies
IL271464B2 (en) 2017-06-30 2024-08-01 Chase Therapeutics Corp NK-1 antagonist compositions and methods for use in the treatment of depression
AU2018392686A1 (en) 2017-12-20 2020-07-09 Corium Pharma Solutions, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
CN110734413A (zh) * 2019-12-02 2020-01-31 山东铂源药业有限公司 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法
CN111333593B (zh) * 2020-04-22 2022-04-29 湖北可赛化工有限公司 一种合成4-甲基-2肼基苯并噻唑的方法
WO2022105644A1 (fr) * 2020-11-19 2022-05-27 四川科伦药物研究院有限公司 Sel de composé benzothiazole, forme cristalline et son utilisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB812512A (en) * 1956-04-12 1959-04-29 Bayer Ag Compositions for combating nematodes
DE2136233A1 (de) * 1971-07-20 1973-02-01 Riedel De Haen Ag Tetrahydrobenzthiazolderivate enthaltende pharmazeutische praeparate
FR2406635A1 (fr) * 1977-10-24 1979-05-18 Logeais Labor Jacques Nouveaux derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique
FR2459239A1 (fr) * 1979-06-20 1981-01-09 Logeais Labor Jacques Nouveaux derives amines du benzothiazole, leur procede de preparation et leur application en therapeutique
DE3027528A1 (de) * 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Ueberbrueckte thiazolyloxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
ZA864626B (en) * 1985-06-24 1988-02-24 Lilly Co Eli Dialkylaminotetrahydrobenzothiazoles and oxazoles

Also Published As

Publication number Publication date
US4843086A (en) 1989-06-27
HUT39736A (en) 1986-10-29
IE58863B1 (en) 1993-11-17
FI81787C (fi) 1990-12-10
NO165070C (no) 1990-12-19
NO165070B (no) 1990-09-10
FI81787B (fi) 1990-08-31
NZ214661A (en) 1990-04-26
MX9202792A (es) 1992-06-30
EP0186087A1 (fr) 1986-07-02
US4731374A (en) 1988-03-15
DK168862B1 (da) 1994-06-27
PT81735B (pt) 1988-04-21
ES556875A0 (es) 1987-08-01
ES8707514B9 (es) 2011-04-14
ATE45735T1 (de) 1989-09-15
FI855102A (fi) 1986-06-23
BG62023B2 (bg) 1998-12-30
KR860004862A (ko) 1986-07-14
ES8707515A1 (es) 1987-08-01
FI855102A0 (fi) 1985-12-20
ES556874A0 (es) 1987-08-01
PH24533A (en) 1990-08-03
NL980002I2 (nl) 1998-05-06
HU193618B (en) 1987-11-30
PT81735A (de) 1986-01-01
AU5154485A (en) 1986-07-17
HK78692A (en) 1992-10-23
DE3572485D1 (en) 1989-09-28
KR930009791B1 (ko) 1993-10-11
NO855195L (no) 1986-06-23
DK590285D0 (da) 1985-12-18
IL77415A (en) 1990-03-19
SG82492G (en) 1992-12-04
CA1263653A (fr) 1989-12-05
US4886812A (en) 1989-12-12
CS409991A3 (en) 1992-09-16
EP0186087B1 (fr) 1989-08-23
IE853270L (en) 1986-06-22
ES8707513A1 (es) 1987-08-01
ES550235A0 (es) 1987-01-16
NL980002I1 (nl) 1998-03-02
ES556873A0 (es) 1987-08-01
GR853126B (fr) 1986-04-22
AU583874B2 (en) 1989-05-11
DK590285A (da) 1986-06-23
ES8707514A1 (es) 1987-08-01
ES8702787A1 (es) 1987-01-16

Similar Documents

Publication Publication Date Title
LU90208I2 (fr) Pramipexole et ses sels dichlorhydrate monohydraté de pramipexole
PT75471A (fr) Procede de preparation d'ethers tricycliques
BG49940A3 (en) Method for preparing derivatives of 4- (4- phenyl- 1- piperazinile)- phenols
SE7710873L (sv) Nya 1h-pyrazolo(3,4-b)pyridiner
PT81545B (pt) Processo para a preparacao de compostos 5-aloquil-1-fenil-2-piperazino-alquil-pirazolin-3-ona
ATE72239T1 (de) Pyrimidinderivate und verfahren zu ihrer herstellung.
HUT39445A (en) Herbicides containing as reagent derivatives of benzodisultam and process for production of the reagents
DK104388D0 (da) Hidtil ukendte 2-(2,3-dihydro-2-oxo-3-benzofuranyl)-eddikesyrederivater, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem
SE8205583D0 (sv) New 5-aminosisoxazole derivatives and processes for producing the same
ATE53839T1 (de) 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
FR2672593B1 (fr) Nouveaux composes utiles pour la resolution de la dl-n-acetyle ou la dl-n-haloacetyl-hydroxyphenylglycine.