PL378587A1 - Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli - Google Patents

Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli

Info

Publication number
PL378587A1
PL378587A1 PL378587A PL37858705A PL378587A1 PL 378587 A1 PL378587 A1 PL 378587A1 PL 378587 A PL378587 A PL 378587A PL 37858705 A PL37858705 A PL 37858705A PL 378587 A1 PL378587 A1 PL 378587A1
Authority
PL
Poland
Prior art keywords
tetrahydrobenzotiazole
propyloamino
salts
amino
methods
Prior art date
Application number
PL378587A
Other languages
English (en)
Inventor
Roman Balicki
Michał Odrowąż-Sypniewski
Agnieszka Ciesielska
Wiesław Szelejewski
Joanna Zagrodzka
Grażyna Cieplucha
Original Assignee
Instytut Farmaceutyczny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Farmaceutyczny filed Critical Instytut Farmaceutyczny
Priority to PL378587A priority Critical patent/PL378587A1/pl
Priority to PCT/PL2006/000093 priority patent/WO2007075095A1/en
Priority to EP06835775A priority patent/EP2051971A1/en
Publication of PL378587A1 publication Critical patent/PL378587A1/pl
Priority to US12/164,005 priority patent/US20090105483A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL378587A 2005-12-29 2005-12-29 Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli PL378587A1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL378587A PL378587A1 (pl) 2005-12-29 2005-12-29 Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli
PCT/PL2006/000093 WO2007075095A1 (en) 2005-12-29 2006-12-29 Process for the preparation of pramipexole base and/or its salts
EP06835775A EP2051971A1 (en) 2005-12-29 2006-12-29 Process for the preparation of pramipexole base and/or its salts
US12/164,005 US20090105483A1 (en) 2005-12-29 2008-06-28 Process for the preparation of pramipexole base and/or its salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL378587A PL378587A1 (pl) 2005-12-29 2005-12-29 Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli

Publications (1)

Publication Number Publication Date
PL378587A1 true PL378587A1 (pl) 2007-07-09

Family

ID=37946221

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378587A PL378587A1 (pl) 2005-12-29 2005-12-29 Sposób wytwarzania (S)-(-)-2-amino-6-n-propyloamino-4,5,6,7-tetrahydrobenzotiazolu i/lub jego soli

Country Status (4)

Country Link
US (1) US20090105483A1 (pl)
EP (1) EP2051971A1 (pl)
PL (1) PL378587A1 (pl)
WO (1) WO2007075095A1 (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
PL2026803T3 (pl) 2006-05-16 2012-05-31 Knopp Neurosciences Inc Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
EP2137171A4 (en) * 2007-03-14 2010-05-19 Knopp Neurosciences Inc SYNTHESIS OF BENZOTHIAZOLE DIAMINES SUBSTITUTED AND PURIFIED FROM THE CHIRAL PERSPECTIVE
US20110190356A1 (en) * 2008-08-19 2011-08-04 Knopp Neurosciences Inc. Compositions and Methods of Using (R)- Pramipexole
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
CN104072442B (zh) * 2013-03-28 2016-09-28 成都弘达药业有限公司 一种化合物及其制备方法
HRP20251187T1 (hr) 2013-07-12 2025-11-21 Areteia Therapeutics, Inc. Liječenje povišenih razina eozinofila i/ili bazofila
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
US9763918B2 (en) 2013-08-13 2017-09-19 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
US9642840B2 (en) 2013-08-13 2017-05-09 Knopp Biosciences, Llc Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders
CN107540633A (zh) * 2016-06-24 2018-01-05 江苏神龙药业有限公司 一种普拉克索及其盐酸盐的工业化制备方法
CN107540632A (zh) * 2016-06-27 2018-01-05 江苏神龙药业股份有限公司 一种普拉克索单盐酸盐的新晶型及其制备方法
CN111072593B (zh) * 2019-12-31 2022-11-08 江苏天和制药有限公司 一种盐酸普拉克索的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3572485D1 (en) * 1984-12-22 1989-09-28 Thomae Gmbh Dr K Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
ES2187249B1 (es) * 2000-09-18 2004-09-16 Synthon Bv Procedimiento para la preparacion de 2-amino-6-(alquil)amino-4,5,6,7-tetrahidrobenzotiazoles.
US7365086B2 (en) * 2003-07-25 2008-04-29 Synthon Ip Inc. Pramipexole acid addition salts
DE602005025988D1 (de) * 2004-03-19 2011-03-03 Dipharma Francis Srl Zwischenprodukte für die herstellung von pramipexol

Also Published As

Publication number Publication date
WO2007075095A1 (en) 2007-07-05
US20090105483A1 (en) 2009-04-23
EP2051971A1 (en) 2009-04-29

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)