ES556874A0 - Procedimiento para preparar nuevos tetrahidro-benzotiazoles. - Google Patents
Procedimiento para preparar nuevos tetrahidro-benzotiazoles.Info
- Publication number
- ES556874A0 ES556874A0 ES556874A ES556874A ES556874A0 ES 556874 A0 ES556874 A0 ES 556874A0 ES 556874 A ES556874 A ES 556874A ES 556874 A ES556874 A ES 556874A ES 556874 A0 ES556874 A0 ES 556874A0
- Authority
- ES
- Spain
- Prior art keywords
- group
- phenyl
- alkyl
- hydrogen atom
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cereal-Derived Products (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Professional, Industrial, Or Sporting Protective Garments (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843447075 DE3447075A1 (de) | 1984-12-22 | 1984-12-22 | Tetrahydro-benzthiazole, deren herstellung und deren verwendung als zwischenprodukte oder als arzneimittel |
DE19853508947 DE3508947A1 (de) | 1985-03-13 | 1985-03-13 | Mittel zur behandlung des parkinsonismus bzw. der parkinsonschen-erkrankung |
ES550235A ES8702787A1 (es) | 1984-12-22 | 1985-12-20 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES556874A0 true ES556874A0 (es) | 1987-08-01 |
ES8707514A1 ES8707514A1 (es) | 1987-08-01 |
Family
ID=25827684
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550235A Expired ES8702787A1 (es) | 1984-12-22 | 1985-12-20 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556873A Expired ES8707513A1 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556874D Expired - Lifetime ES8707514B9 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556874A Expired ES8707514A1 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556875A Expired ES8707515A1 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550235A Expired ES8702787A1 (es) | 1984-12-22 | 1985-12-20 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556873A Expired ES8707513A1 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
ES556874D Expired - Lifetime ES8707514B9 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556875A Expired ES8707515A1 (es) | 1984-12-22 | 1986-07-03 | Procedimiento para preparar nuevos tetrahidro-benzotiazoles |
Country Status (25)
Country | Link |
---|---|
US (3) | US4731374A (es) |
EP (1) | EP0186087B1 (es) |
KR (1) | KR930009791B1 (es) |
AT (1) | ATE45735T1 (es) |
AU (1) | AU583874B2 (es) |
BG (1) | BG62023B2 (es) |
CA (1) | CA1263653A (es) |
CS (1) | CS409991A3 (es) |
DE (1) | DE3572485D1 (es) |
DK (1) | DK168862B1 (es) |
ES (5) | ES8702787A1 (es) |
FI (1) | FI81787C (es) |
GR (1) | GR853126B (es) |
HK (1) | HK78692A (es) |
HU (1) | HU193618B (es) |
IE (1) | IE58863B1 (es) |
IL (1) | IL77415A (es) |
LU (1) | LU90208I2 (es) |
MX (1) | MX9202792A (es) |
NL (1) | NL980002I2 (es) |
NO (1) | NO165070C (es) |
NZ (1) | NZ214661A (es) |
PH (1) | PH24533A (es) |
PT (1) | PT81735B (es) |
SG (1) | SG82492G (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8952173B2 (en) | 2005-05-09 | 2015-02-10 | Crystal Pharma, S.A.U. | Method for the resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazol and intermediate compounds |
Families Citing this family (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3620813A1 (de) * | 1986-06-21 | 1987-12-23 | Boehringer Ingelheim Kg | Neue tetrahydro-benzothiazole, ihre herstellung und verwendung |
US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
US4988699A (en) * | 1989-03-14 | 1991-01-29 | Warner-Lambert Company | Substituted tetrahydrobenzothiazoles as dopaminergic agents |
DE3923689A1 (de) * | 1989-07-18 | 1991-01-24 | Boehringer Ingelheim Kg | Neue verwendung von tetrahydrobenzthiazolderivaten als arzneistoffe |
DE3930282A1 (de) * | 1989-09-11 | 1991-03-21 | Boehringer Ingelheim Kg | Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit |
DE3937271A1 (de) * | 1989-11-09 | 1991-05-16 | Boehringer Ingelheim Kg | Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol |
FR2674853B1 (fr) * | 1991-04-03 | 1995-01-20 | Synthelabo | Derives de piperidinylguanidine, leur preparation et leur application en therapeutique. |
DE4241013A1 (de) | 1992-12-05 | 1994-06-09 | Boehringer Ingelheim Kg | Verwendung von 2-Amino-6-n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol als Arzneimittel mit antidepressiver Wirkung |
US6156777A (en) * | 1994-12-15 | 2000-12-05 | Pharmacia & Upjohn Company | Use of pramipexole as a neuroprotective agent |
US5650420A (en) * | 1994-12-15 | 1997-07-22 | Pharmacia & Upjohn Company | Pramipexole as a neuroprotective agent |
DE19507752A1 (de) * | 1995-03-06 | 1996-09-12 | Bayer Ag | Verfahren zur Herstellung von substituierten Cyclohexanonen |
DE19536916A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Kg | Inhalative Applikation von 2-Amino-6n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol, insbesondere seines (-)-Enantiomeren, sowie deren pharmakologisch verträgliche Säureadditionssalze |
CZ370198A3 (cs) * | 1996-05-31 | 1999-05-12 | Pharmacia & Upjohn Company | Aryl substituované cyklické aminy jako selektivní dopaminové D3 ligandy |
US6001861A (en) | 1998-01-16 | 1999-12-14 | Pharmacia & Upjohn Company | Use of pramipexole in the treatment of restless legs syndrome |
DE19701619B4 (de) * | 1997-01-17 | 2007-10-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Pramipexol zur Behandlung des restless legs syndroms |
AU760439B2 (en) * | 1998-05-15 | 2003-05-15 | Pharmacia & Upjohn Company | Cabergoline and pramipexole: new uses and combinations |
SE9802360D0 (sv) | 1998-07-01 | 1998-07-01 | Wikstroem Hakan Vilhelm | New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin |
DE19830201A1 (de) * | 1998-07-07 | 2000-01-13 | Boehringer Ingelheim Pharma | Mittel mit antidepressiver Wirkung |
US6232326B1 (en) | 1998-07-14 | 2001-05-15 | Jodi A. Nelson | Treatment for schizophrenia and other dopamine system dysfunctions |
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CN110734413A (zh) * | 2019-12-02 | 2020-01-31 | 山东铂源药业有限公司 | 一种普拉克索中间体2,6-二氨基-4,5,6,7-四氢苯并噻唑的制备方法 |
CN111333593B (zh) * | 2020-04-22 | 2022-04-29 | 湖北可赛化工有限公司 | 一种合成4-甲基-2肼基苯并噻唑的方法 |
EP4249476A1 (en) * | 2020-11-19 | 2023-09-27 | Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. | Salt of benzothiazole compound, and crystal form and use thereof |
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GB812512A (en) * | 1956-04-12 | 1959-04-29 | Bayer Ag | Compositions for combating nematodes |
DE2136233A1 (de) * | 1971-07-20 | 1973-02-01 | Riedel De Haen Ag | Tetrahydrobenzthiazolderivate enthaltende pharmazeutische praeparate |
FR2406635A1 (fr) * | 1977-10-24 | 1979-05-18 | Logeais Labor Jacques | Nouveaux derives du benzo(d)thiazole, leur procede de preparation et leurs applications en therapeutique |
FR2459239A1 (fr) * | 1979-06-20 | 1981-01-09 | Logeais Labor Jacques | Nouveaux derives amines du benzothiazole, leur procede de preparation et leur application en therapeutique |
DE3027528A1 (de) * | 1980-07-19 | 1982-02-18 | Basf Ag, 6700 Ludwigshafen | Ueberbrueckte thiazolyloxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
EP0207696A1 (en) * | 1985-06-24 | 1987-01-07 | Eli Lilly And Company | Dialkylaminotetrahydrobenzothiazoles and oxazoles |
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1985
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1988
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8952173B2 (en) | 2005-05-09 | 2015-02-10 | Crystal Pharma, S.A.U. | Method for the resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazol and intermediate compounds |
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