LU86411A1 - Procede de preparation de derives n7-amidino-substitutes de la mitomycine c. - Google Patents

Procede de preparation de derives n7-amidino-substitutes de la mitomycine c. Download PDF

Info

Publication number
LU86411A1
LU86411A1 LU86411A LU86411A LU86411A1 LU 86411 A1 LU86411 A1 LU 86411A1 LU 86411 A LU86411 A LU 86411A LU 86411 A LU86411 A LU 86411A LU 86411 A1 LU86411 A1 LU 86411A1
Authority
LU
Luxembourg
Prior art keywords
mitomycin
reaction
amino
methoxymitosan
carried out
Prior art date
Application number
LU86411A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU86411A1 publication Critical patent/LU86411A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LU86411A 1985-04-29 1986-04-28 Procede de preparation de derives n7-amidino-substitutes de la mitomycine c. LU86411A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/728,650 US4652644A (en) 1985-04-29 1985-04-29 Process for preparation of N7 -amidino substituted mitomycin C derivatives
US72865085 1985-04-29

Publications (1)

Publication Number Publication Date
LU86411A1 true LU86411A1 (fr) 1986-11-05

Family

ID=24927725

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86411A LU86411A1 (fr) 1985-04-29 1986-04-28 Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.

Country Status (21)

Country Link
US (1) US4652644A (da)
KR (1) KR910002080B1 (da)
CN (1) CN1020731C (da)
AR (1) AR242210A1 (da)
AT (1) AT394724B (da)
CA (1) CA1247617A (da)
CS (1) CS271331B2 (da)
DD (1) DD258011A5 (da)
DK (1) DK168708B1 (da)
ES (1) ES8706685A1 (da)
FI (1) FI83519C (da)
GR (1) GR861152B (da)
HU (1) HU194243B (da)
IT (1) IT1208605B (da)
LU (1) LU86411A1 (da)
NO (1) NO164543C (da)
OA (1) OA08243A (da)
PT (1) PT82471B (da)
SU (1) SU1436881A3 (da)
YU (1) YU45778B (da)
ZW (1) ZW5386A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPH0867676A (ja) * 1994-03-30 1996-03-12 Eisai Kagaku Kk 保護アミノチアゾリル酢酸誘導体
JP3202960B2 (ja) * 1998-02-17 2001-08-27 大塚化学株式会社 ハロゲン化剤及び水酸基のハロゲン化方法
CN104710426B (zh) * 2014-12-12 2017-08-01 常州大学 苯并吡咯里西啶生物碱及其制备方法和用途
CN104478885B (zh) * 2014-12-12 2017-08-01 常州大学 9‑氨基‑9a‑烯丙基苯并吡咯里西啶生物碱的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1135270B (it) * 1980-04-12 1986-08-20 Erba Farmitalia 3-amidino-ansamicine
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4567256A (en) * 1983-05-09 1986-01-28 Bristol-Myers Company Amidine process

Also Published As

Publication number Publication date
CS271331B2 (en) 1990-09-12
FI861720A0 (fi) 1986-04-24
IT1208605B (it) 1989-07-10
AT394724B (de) 1992-06-10
ES8706685A1 (es) 1987-07-01
HU194243B (en) 1988-01-28
GR861152B (en) 1986-09-02
KR860008201A (ko) 1986-11-12
US4652644A (en) 1987-03-24
NO861652L (no) 1986-10-30
OA08243A (fr) 1987-10-30
YU70086A (en) 1987-12-31
FI83519C (fi) 1991-07-25
DK193786D0 (da) 1986-04-28
CN1020731C (zh) 1993-05-19
NO164543C (no) 1990-10-17
HUT40665A (en) 1987-01-28
FI83519B (fi) 1991-04-15
CN86101611A (zh) 1986-12-17
ATA101886A (de) 1991-11-15
IT8620228A0 (it) 1986-04-28
AR242210A1 (es) 1993-03-31
PT82471A (en) 1986-05-01
CS311786A2 (en) 1989-12-13
YU45778B (sh) 1992-07-20
ES554469A0 (es) 1987-07-01
NO164543B (no) 1990-07-09
DD258011A5 (de) 1988-07-06
DK193786A (da) 1986-10-30
KR910002080B1 (ko) 1991-04-03
CA1247617A (en) 1988-12-28
ZW5386A1 (en) 1986-10-01
PT82471B (pt) 1988-10-14
DK168708B1 (da) 1994-05-24
FI861720A (fi) 1986-10-30
SU1436881A3 (ru) 1988-11-07

Similar Documents

Publication Publication Date Title
EP3626699B1 (en) Ssao inhibitor
EP0313724B1 (en) Bis (acyloxymethyl) imidazole Derivative
CH639653A5 (fr) Aminothiazoles et composition pharmaceutique les contenant.
FR2823209A1 (fr) Nouvelles thiohydantoines et leur utilisation en therapeutique
EP2020410B1 (fr) Dérivés de pyrido[2,3-d] pyrimidine, leur préparation, leur application en thérapeutique
LU84843A1 (fr) Amidines
EP0447324B1 (fr) Dérivés de pyrimidinedione-2,4 et médicaments les contenant
EP0092458A2 (fr) Dérives d'imidazo(1,2-a)pyridine, leur préparation et leur application en thérapeutique
EP3418273A1 (fr) Dérivés de flavaglines
EP2185561B1 (fr) Dérivés de 1,2,3,4-tétrahydropyrrolo(1,2-a)pyrazine-6-carboxamides et de 2,3,4,5-tétrahydropyrrolo(1,2-a)-diazépine-7-carboxamides, leur préparation et leur application en thérapeutique
JPH054985A (ja) 新規な化合物
FR2580642A1 (fr) 5-pyrimidinecarboxamides et traitement de la leucemie et des tumeurs en les utilisant
EP0303871B1 (fr) Oxadiazolo pyrimidinones, leur préparation et leur utilisation en cosmétique et dermopharmacie
LU86411A1 (fr) Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.
EP0432209B1 (fr) Composes phenylpyrroliques utiles en tant que medicaments, leur preparation et leur application
FR2543953A1 (fr) Analogue de la mitomycine comportant un groupe disulfure, leur preparation et leur application pharmacologique
LU84144A1 (fr) Analogues de la mitomycine
EP0263506B1 (en) Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative
JP2004528293A (ja) ピリミジン化合物並びに該化合物の製造及び使用方法
LU85711A1 (fr) Acylaminomitosanes
FR2569696A1 (fr) Nouveaux analogues de la mitomycine, leur procede de preparation et leur application pharmaceutique
CA2087656A1 (en) New compounds
Contant et al. A new convergent synthesis of thiamine hydrochloride
US20230126480A1 (en) Benzo 2-azaspiro[4.4]nonane compound and use thereof
FR2615188A1 (fr) Derives d'hydrazine, procede d'obtention et compositions pharmaceutiques les contenant