LU84044A1 - Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique - Google Patents

Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique Download PDF

Info

Publication number
LU84044A1
LU84044A1 LU84044A LU84044A LU84044A1 LU 84044 A1 LU84044 A1 LU 84044A1 LU 84044 A LU84044 A LU 84044A LU 84044 A LU84044 A LU 84044A LU 84044 A1 LU84044 A1 LU 84044A1
Authority
LU
Luxembourg
Prior art keywords
methoxy
naphthyl
halo
approximately
propionic
Prior art date
Application number
LU84044A
Other languages
English (en)
French (fr)
Inventor
Vincenzo Cannata
Giancarlo Tamerlani
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11106122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU84044(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Publication of LU84044A1 publication Critical patent/LU84044A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU84044A 1981-04-01 1982-03-30 Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique LU84044A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT338581 1981-04-01
IT03385/81A IT1168387B (it) 1981-04-01 1981-04-01 Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Publications (1)

Publication Number Publication Date
LU84044A1 true LU84044A1 (fr) 1983-02-22

Family

ID=11106122

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84044A LU84044A1 (fr) 1981-04-01 1982-03-30 Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique

Country Status (26)

Country Link
US (1) US4423244A (es)
JP (1) JPS57176925A (es)
KR (1) KR860001547B1 (es)
AR (1) AR230614A1 (es)
AT (1) AT390253B (es)
BE (1) BE892689A (es)
CA (1) CA1190939A (es)
CH (1) CH651289A5 (es)
DE (1) DE3212170A1 (es)
DK (2) DK157076C (es)
ES (1) ES8302622A1 (es)
FI (1) FI78455C (es)
FR (1) FR2504918B1 (es)
GB (1) GB2098981B (es)
GR (1) GR76062B (es)
HU (1) HU186852B (es)
IE (1) IE52378B1 (es)
IL (1) IL65298A (es)
IT (1) IT1168387B (es)
LU (1) LU84044A1 (es)
NL (1) NL8201307A (es)
NO (1) NO157733B (es)
PT (1) PT74677B (es)
SE (2) SE453492C (es)
YU (1) YU42606B (es)
ZA (1) ZA822145B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191845B (en) * 1982-05-27 1987-04-28 Syntex Pharma Int Process for the production of /d/-2-/6-methoxy-2-naphthyl/-propionic acid and of its therapeutically acceptabel salts
FI831820L (fi) * 1982-05-27 1983-11-28 Syntex Pharma Int Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
US4723033A (en) * 1982-11-24 1988-02-02 Syntex Pharmaceuticals International Ltd. Manufacture of optically active α-arylalkanoic acids and precursors thereof
IT1174084B (it) * 1984-05-10 1987-07-01 Blaschim Spa Procentimento per preparare il naproxen
US4814497A (en) * 1986-05-12 1989-03-21 Ethyl Corporation Dehalogenation process
IT1238008B (it) * 1990-02-08 1993-06-21 Alfa Wassermann Spa Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni
FR2686877B1 (fr) * 1992-01-31 1995-03-24 Hoechst France Procede de preparation de l'acide orthohydroxyphenylacetique.
JPH0646907U (ja) * 1992-12-10 1994-06-28 リョービ株式会社 すべり勾配面加工用治具
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3637767A (en) * 1968-07-30 1972-01-25 Syntex Corp 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
CA936171A (en) * 1970-09-09 1973-10-30 Syntex Corporation Process for preparing 2-(6-methoxy-2-naphthyl) propionic acid and 2-(6-methoxy-2-naphthyl)-1-propanol
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Also Published As

Publication number Publication date
JPH0231704B2 (es) 1990-07-16
YU72082A (en) 1985-03-20
DK256589A (da) 1989-05-26
US4423244B1 (es) 1987-07-28
DK157076B (da) 1989-11-06
SE8501744D0 (sv) 1985-04-09
IE52378B1 (en) 1987-09-30
YU42606B (en) 1988-10-31
BE892689A (fr) 1982-09-30
NO157733B (no) 1988-02-01
PT74677B (en) 1983-10-31
FI78455B (fi) 1989-04-28
ES510931A0 (es) 1983-02-01
AT390253B (de) 1990-04-10
GR76062B (es) 1984-08-03
NO821088L (no) 1982-10-04
US4423244A (en) 1983-12-27
DK157076C (da) 1990-04-09
IT1168387B (it) 1987-05-20
SE8202050L (sv) 1982-10-02
JPS57176925A (en) 1982-10-30
FI78455C (fi) 1989-08-10
CH651289A5 (de) 1985-09-13
FI821121L (fi) 1982-10-02
IL65298A (en) 1985-02-28
GB2098981A (en) 1982-12-01
HU186852B (en) 1985-10-28
DK147482A (da) 1982-10-02
SE453492C (sv) 1994-09-15
CA1190939A (en) 1985-07-23
SE466199B (sv) 1992-01-13
AR230614A1 (es) 1984-05-31
PT74677A (en) 1982-04-01
FR2504918A1 (fr) 1982-11-05
GB2098981B (en) 1984-10-24
KR860001547B1 (ko) 1986-10-04
FR2504918B1 (fr) 1985-06-14
DE3212170A1 (de) 1982-10-21
IT8103385A0 (it) 1981-04-01
SE453492B (sv) 1988-02-08
DE3212170C2 (es) 1989-03-02
NL8201307A (nl) 1982-11-01
FI821121A0 (fi) 1982-03-31
ATA127082A (de) 1989-09-15
DK256589D0 (da) 1989-05-26
ES8302622A1 (es) 1983-02-01
SE8501744L (sv) 1985-04-09
ZA822145B (en) 1983-02-23
IL65298A0 (en) 1982-05-31
KR830008973A (ko) 1983-12-16
IE820770L (en) 1982-10-01

Similar Documents

Publication Publication Date Title
CH647523A5 (fr) Solvats d'ethers alicycliques et d'un acide cephem-4-carboxylique, leur preparation et leur utilisation pour l'obtention de l'acide et de ses sels.
LU84044A1 (fr) Nouveau procede de preparation de l'acide d-2(6-metoxy-2-naphtyl)propionique
JPH11511742A (ja) １−アミノインダン−２−オールによるキラル酸分離プロセス
FR2832146A1 (fr) Base libre de tamsulosine racemique et ses procedes de preparation
CH648314A5 (fr) Procede de preparation de trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido(4,3-b)-indoles substitues en position 2 et composes permettant de les obtenir.
CH666888A5 (fr) Procede de dedoublement optique d'un derive de l'acide phenylacetique.
US5621140A (en) Resolution of ibuprofen
EP0303545B1 (fr) Procédé pour la préparation de phényléthanolaminotétralines
EP2170801A1 (fr) Nouveau procede de synthese du fenofibrate
BE1009080A4 (fr) Procede de preparation de l'epibatidine.
JP3888402B2 (ja) 光学活性Ｎ−カルボベンゾキシ−ｔｅｒｔ−ロイシンの製造法
EP0251904B1 (fr) Procédé de préparation du maléate acide de lévomépromazine
NL8520047A (nl) Werkwijze voor het bereiden van n-acylphenylalanines.
JPH10218847A (ja) タートラニル酸の製造法
US6093846A (en) Process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid
JPH0751090A (ja) 光学活性３−アミノブタン酸の製造法及びそのエステル中間体
FR2653765A1 (fr) Procede pour la preparation enantioselective de 2-aminotetralines.
JP2003137835A (ja) （ｒ）−３−ヒドロキシ−３−（２−フェニルエチル）ヘキサン酸の製造方法
FR2847579A1 (fr) Racemisation d'esters de phenylglycine 2-substitues optiquement actifs
EP0124407B1 (fr) Procédé de préparation d'acides alkanoiques
BE506331A (es)
JPH03200739A (ja) 光学活性２−ヒドロキシ−４−フェニル酪酸アルキルエステルの製造法
EP0627402B1 (fr) Procédé d'obtention d'acides hydroxyphénylacétiques
EP2358665A1 (fr) Procede de preparation de l'hemifumarate d'eplivanserine
FR2567881A1 (fr) Procede pour la production d'un derive de pyrrolidine