LU81763A1 - Procede de preparation du sulfate de vindesine - Google Patents

Procede de preparation du sulfate de vindesine Download PDF

Info

Publication number
LU81763A1
LU81763A1 LU81763A LU81763A LU81763A1 LU 81763 A1 LU81763 A1 LU 81763A1 LU 81763 A LU81763 A LU 81763A LU 81763 A LU81763 A LU 81763A LU 81763 A1 LU81763 A1 LU 81763A1
Authority
LU
Luxembourg
Prior art keywords
vindesin
sulfuric acid
vindesine
monosulfate
acetonitrile
Prior art date
Application number
LU81763A
Other languages
English (en)
French (fr)
Inventor
S Rolski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of LU81763A1 publication Critical patent/LU81763A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
LU81763A 1978-10-10 1979-10-08 Procede de preparation du sulfate de vindesine LU81763A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94959578A 1978-10-10 1978-10-10
US94959578 1978-10-10

Publications (1)

Publication Number Publication Date
LU81763A1 true LU81763A1 (fr) 1980-01-24

Family

ID=25489302

Family Applications (1)

Application Number Title Priority Date Filing Date
LU81763A LU81763A1 (fr) 1978-10-10 1979-10-08 Procede de preparation du sulfate de vindesine

Country Status (32)

Country Link
EP (1) EP0009996B1 (de)
JP (1) JPS5553295A (de)
KR (1) KR850000150B1 (de)
AR (1) AR225153A1 (de)
AT (1) AT370422B (de)
AU (1) AU525702B2 (de)
BE (1) BE879213A (de)
BG (1) BG34763A3 (de)
CA (1) CA1114817A (de)
CH (2) CH645120A5 (de)
CS (1) CS235503B2 (de)
DD (1) DD146461A5 (de)
DE (1) DE2964913D1 (de)
DK (1) DK146823C (de)
EG (1) EG14140A (de)
ES (1) ES484827A1 (de)
FI (1) FI70223C (de)
FR (1) FR2438659A1 (de)
GB (1) GB2031893B (de)
GR (1) GR72394B (de)
HU (1) HU180744B (de)
IE (1) IE48958B1 (de)
IL (1) IL58390A (de)
LU (1) LU81763A1 (de)
MY (1) MY8500569A (de)
NZ (1) NZ191744A (de)
PH (1) PH16092A (de)
PL (1) PL117678B1 (de)
PT (1) PT70269A (de)
RO (1) RO77380A (de)
YU (1) YU241179A (de)
ZA (1) ZA795268B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) * 2020-12-22 2022-03-22 海南长春花药业有限公司 一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
GR69783B (de) * 1976-09-08 1982-07-07 Lilly Co Eli

Also Published As

Publication number Publication date
KR830001282A (ko) 1983-04-30
CH645120A5 (fr) 1984-09-14
GB2031893A (en) 1980-04-30
FR2438659B1 (de) 1983-03-18
AT370422B (de) 1983-03-25
FI793065A (fi) 1980-04-11
KR850000150B1 (ko) 1985-02-28
FI70223B (fi) 1986-02-28
FR2438659A1 (fr) 1980-05-09
IE48958B1 (en) 1985-06-26
RO77380A (ro) 1981-11-04
DE2964913D1 (en) 1983-03-31
GR72394B (de) 1983-11-01
CS235503B2 (en) 1985-05-15
AR225153A1 (es) 1982-02-26
DD146461A5 (de) 1981-02-11
IE791914L (en) 1980-04-10
GB2031893B (en) 1983-03-30
DK146823B (da) 1984-01-16
AU5142779A (en) 1980-04-17
YU241179A (en) 1983-01-21
DK422979A (da) 1980-04-11
PH16092A (en) 1983-06-20
PL218756A1 (de) 1980-06-16
MY8500569A (en) 1985-12-31
BG34763A3 (en) 1983-11-15
IL58390A0 (en) 1980-01-31
FI70223C (fi) 1986-09-15
CH649301A5 (fr) 1985-05-15
EP0009996B1 (de) 1983-02-23
EG14140A (en) 1983-09-30
JPS628119B2 (de) 1987-02-20
AU525702B2 (en) 1982-11-25
DK146823C (da) 1984-07-02
IL58390A (en) 1982-07-30
PL117678B1 (en) 1981-08-31
ATA658279A (de) 1982-08-15
NZ191744A (en) 1981-05-29
ES484827A1 (es) 1980-10-01
BE879213A (fr) 1980-04-08
HU180744B (en) 1983-04-29
JPS5553295A (en) 1980-04-18
EP0009996A1 (de) 1980-04-16
CA1114817A (en) 1981-12-22
ZA795268B (en) 1981-05-27
PT70269A (de) 1979-11-01

Similar Documents

Publication Publication Date Title
EP0078785B1 (de) Salze der Valproinsäure, ihre Herstellung und ihre Verwendung
EP0010458B1 (de) Bis-Indole-Verbindungen, sie enthaltende pharmazeutische Zusammensetzungen, Verfahren zu ihrer Herstellung
CH639070A5 (fr) 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo(cd)indole et composition pharmaceutique en contenant.
LU83423A1 (fr) Pneumatique radial pour vehicules tout-terrain
LU84143A1 (fr) Procede de preparation d'un polysulfate de chondroitine injectable,produit obtenu par ce procede et compositions pharmaceutiques le contenant
EP0840720B1 (de) Verfahren zur herstellung jodierter fettsäuren und ihrer derivate durch jodwasserstoffanlagerung unter anwendung von alkylsilylderivaten mit alkalijodiden und deren pharmakologischen aktivitäten
EP0479631B1 (de) Spiro[4,5]decanderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
LU81763A1 (fr) Procede de preparation du sulfate de vindesine
FR2616429A1 (fr) Procede de preparation du 1,2,5,6,9,10-hexabromocyclododecane
EP1664044B1 (de) S-tenatoprazolnatrium-monohydrat-salz und dessen verwendung in form eines protonenpumpenhemmers
FR2650280A1 (fr) (2r,cis)-1,2-epoxypropyl-phosphonate de mono-(2-ammonium-2-hydroxymethyl-1,3-propanediol) ayant des caracteristiques ameliorees de stabilite, son procede de preparation et compositions pharmaceutiques le contenant
DE3443467A1 (de) Mercaptanderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0134729B1 (de) Verfahren zur Herstellung von Globin aus Haemoglobin und das in diesem Verfahren erhaltene Globin
EP0092287B1 (de) Acetylcystein-Salze, ihre Herstellung und Verwendung
EP0117861B1 (de) Verfahren zur Herstellung von Vincristin
CH616918A5 (de)
EP2486019A1 (de) Verfahren zur synthese von 2-thiohistidin und dergleichen
KR102305089B1 (ko) 멍게체액 추출물의 제조방법
CA1210762A (fr) Methode de preparation de vincristine
EP0017525B1 (de) Derivate von Tetrahydroalstonin, ihre Herstellung und ihre Verwendung in Arzneimitteln
FR2491927A1 (fr) Derives de cephalexine solubles dans l'eau, et procede pour leur preparation
FR2616788A1 (fr) Procede pour la fabrication d'esters du 1-methyl-10a-methoxy-lu milysergol
JPH0128752B2 (de)
FR2582657A1 (fr) Procede de preparation de sels d'heparine
FR2477155A1 (en) Ergocornine, alpha and beta ergocryptine prodn. - by epimerisation of C-8 epimers, ergocornine and ergocryptine(s) with acid in organic solvents