LT4736B - Farmacinės kompozicijos, turinčios plazmos proteino - Google Patents

Farmacinės kompozicijos, turinčios plazmos proteino Download PDF

Info

Publication number
LT4736B
LT4736B LT2000018A LT2000018A LT4736B LT 4736 B LT4736 B LT 4736B LT 2000018 A LT2000018 A LT 2000018A LT 2000018 A LT2000018 A LT 2000018A LT 4736 B LT4736 B LT 4736B
Authority
LT
Lithuania
Prior art keywords
water
product
pharmaceutical composition
serum albumin
plasma
Prior art date
Application number
LT2000018A
Other languages
English (en)
Lithuanian (lt)
Other versions
LT2000018A (en
Inventor
Lajos Hegedues
Krisztina Krempels
Krisztina Paal
Gabor Petho
Original Assignee
Human Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Rt. filed Critical Human Rt.
Publication of LT2000018A publication Critical patent/LT2000018A/xx
Publication of LT4736B publication Critical patent/LT4736B/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LT2000018A 1997-09-18 2000-03-17 Farmacinės kompozicijos, turinčios plazmos proteino LT4736B (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9701554A HUP9701554D0 (en) 1997-09-18 1997-09-18 Pharmaceutical composition containing plazma proteins

Publications (2)

Publication Number Publication Date
LT2000018A LT2000018A (en) 2000-08-25
LT4736B true LT4736B (lt) 2000-12-27

Family

ID=90014222

Family Applications (1)

Application Number Title Priority Date Filing Date
LT2000018A LT4736B (lt) 1997-09-18 2000-03-17 Farmacinės kompozicijos, turinčios plazmos proteino

Country Status (33)

Country Link
US (5) US6743826B1 (sr)
EP (1) EP0981375B1 (sr)
JP (1) JP2001508806A (sr)
KR (1) KR100587962B1 (sr)
CN (1) CN1189216C (sr)
AR (1) AR017120A1 (sr)
AT (1) ATE230611T1 (sr)
AU (1) AU734695B2 (sr)
BG (1) BG64749B1 (sr)
BR (1) BR9812469A (sr)
CA (1) CA2269923C (sr)
CZ (1) CZ301326B6 (sr)
DE (1) DE69810612T2 (sr)
DK (1) DK0981375T3 (sr)
EA (1) EA004700B1 (sr)
ES (1) ES2187062T3 (sr)
HR (1) HRP980499A2 (sr)
HU (1) HUP9701554D0 (sr)
IL (1) IL135055A (sr)
LT (1) LT4736B (sr)
LV (1) LV12493B (sr)
NO (1) NO325294B1 (sr)
NZ (1) NZ503302A (sr)
PL (1) PL193067B1 (sr)
PT (1) PT981375E (sr)
RO (1) RO118695B1 (sr)
RS (1) RS50102B (sr)
SI (1) SI20189B (sr)
SK (1) SK284683B6 (sr)
TR (1) TR200001545T2 (sr)
TW (1) TWI222365B (sr)
WO (1) WO1999013914A1 (sr)
ZA (1) ZA988585B (sr)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US8137684B2 (en) * 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
HUP9701554D0 (en) * 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins
WO2000047187A1 (en) * 1999-02-11 2000-08-17 Kinetana Inc. Serum albumin-based parenteral formulations of polyene macrolides
IL148234A0 (en) 1999-09-16 2002-09-12 Novo Nordisk As Composition for ivf
AU2001253336A1 (en) * 2000-04-10 2001-10-23 Teva Pharmaceutical Industries Ltd. Method 0f administration of paclitaxel-plasma protein formulation
IL152180A0 (en) * 2000-04-10 2003-05-29 Teva Pharma Method and composition for treating cancer by administration of apoptosis-inducing chemotherapeutic agents
CA2445763A1 (en) * 2001-05-01 2002-11-07 Angiotech Pharmaceuticals Inc. Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions
EP2261250B1 (en) 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
GR1004274B (el) 2002-07-16 2003-06-23 Medexis ���� Συμπλοκα στεροειδων ορμονων με πρωτεινες: νεες ουσιες για την ειδικη ανιχνευση και καταστροφη καρκινικων κυτταρων προερχομενων απο στερεους ογκους και αιματολογικες κακοηθειες
CA2492297A1 (en) 2002-07-16 2004-01-22 Medexis S.A. Steroid conjugates, preparation thereof and the use thereof
AU2003262025A1 (en) * 2002-09-12 2004-04-30 Nihon Medi-Physics Co., Ltd. Preparation for controlling binging of drug to plasma protein
KR20200083657A (ko) 2002-12-09 2020-07-08 아브락시스 바이오사이언스, 엘엘씨 약리학적 물질의 조성물 및 그 전달방법
WO2004101620A2 (en) * 2003-05-01 2004-11-25 Compound Therapeutics, Inc. Serum albumin scaffold-based proteins and uses thereof
US20040225022A1 (en) * 2003-05-09 2004-11-11 Desai Neil P. Propofol formulation containing reduced oil and surfactants
US7659310B2 (en) 2004-04-27 2010-02-09 Formatech, Inc. Methods of enhancing solubility of agents
US7345093B2 (en) 2004-04-27 2008-03-18 Formatech, Inc. Methods of enhancing solubility of compounds
US20050277584A1 (en) * 2004-06-09 2005-12-15 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
EP1807146A4 (en) * 2004-09-29 2013-07-03 Tel Hashomer Medical Res Infrastructure & Services Ltd COMPOSITION FOR IMPROVING THE EFFICACY OF DRUG DELIVERY
US20060198891A1 (en) * 2004-11-29 2006-09-07 Francois Ravenelle Solid formulations of liquid biologically active agents
US7507842B2 (en) 2005-08-12 2009-03-24 Radiorx, Inc. Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof
EP2066309B1 (en) 2007-04-04 2012-08-29 Sigmoid Pharma Limited An oral pharmaceutical composition
EP2061587A1 (en) 2007-04-26 2009-05-27 Sigmoid Pharma Limited Manufacture of multiple minicapsules
WO2009116557A1 (ja) * 2008-03-21 2009-09-24 富士フイルム株式会社 薬剤含有組成物
CN101658516B (zh) * 2008-08-26 2011-10-05 齐鲁制药有限公司 紫杉醇类药物组合物及其制备方法
CA2762179A1 (en) 2009-05-18 2010-11-25 Sigmoid Pharma Limited Composition comprising oil drops
CN107582526A (zh) 2009-08-12 2018-01-16 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
US10143652B2 (en) 2009-09-23 2018-12-04 Curirx Inc. Methods for the preparation of liposomes
EP2480208A1 (en) 2009-09-23 2012-08-01 Indu Javeri Methods for the preparation of liposomes
US9629920B2 (en) 2009-12-18 2017-04-25 Exodos Life Sciences Limited Partnership Methods and compositions for stable liquid drug formulations
WO2011097149A2 (en) * 2010-02-03 2011-08-11 Oncbiomune, L.L.C. Taxane-and taxoid-protein compositions
AR093275A1 (es) 2010-03-17 2015-05-27 Centro De Excelencia En Productos Y Procesos De Cordoba (Ceprocor) Una composicion farmaceutica soluble en agua que comprende al menos una sustancia terapeuticamente activa de caracteristicas hidrofobicas y al menos un compuesto seleccionado entre los sialoglicoesfingolipidos, los glicoesfingolipidos o una mezcla de sialoglicoesfingolipidos y glicoesfingolipidos
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
AU2015232994B2 (en) 2014-03-18 2020-05-28 Izun Pharmaceuticals Corp. Protein-bound cannabinoid compositions
AU2015341695B2 (en) 2014-11-07 2021-07-08 Sublimity Therapeutics Limited Compositions comprising cyclosporin
AR100034A1 (es) 2015-01-30 2016-09-07 Consejo Nac De Investig Científicas Y Técnicas (Conicet) Una composición farmacéutica soluble en agua que comprende, al menos, una sustancia terapéuticamente activa y, al menos, una sustancia con capacidad para formar micelas
EP3294900B1 (en) * 2015-05-08 2021-09-22 Spectral Platforms, Inc. Use of albumin-based non-covalent complexes for the detection of micro-organisms
CN112807299B (zh) 2015-05-15 2022-06-24 珠海贝海生物技术有限公司 包含多西他赛和人血清白蛋白的固体组合物及其制备方法和应用
EP3310338A4 (en) * 2015-06-18 2018-12-26 Matinas BioPharma Nanotechnologies, Inc. Compositions and methods for treating inflammatory disease or conditions
WO2017083397A1 (en) * 2015-11-09 2017-05-18 Cayo Max A Cardiac glycosides for the treatment of hypercholesterolemia
WO2018027029A1 (en) * 2016-08-03 2018-02-08 Zhuhai Beihai Biotech Co., Ltd. Formulations of fosaprepitant and aprepitant
CN110062622B (zh) 2016-10-27 2022-10-14 珠海贝海生物技术有限公司 多西他赛和人血清白蛋白的中性pH组合物
RU2019131436A (ru) 2017-03-09 2021-04-10 Изун Фармасьютикалс Корп. Стабилизированные композиции связанных с белком каннабиоидов
US11105747B2 (en) 2017-03-20 2021-08-31 Spectral Platforms, Inc. Spectroscopic methods to detect and characterize microorganisms
MX2020000265A (es) 2017-07-07 2020-07-22 Epicentrx Inc Composiciones para la administración parenteral de agentes terapéuticos.
AU2019232153B2 (en) * 2018-03-09 2023-07-13 Panoptes Pharma Ges.M.B.H. Ophthalmic formulation
EP3811982A1 (en) * 2019-10-25 2021-04-28 Université de Strasbourg Protein-based biomaterial with viscoelastic behaviour, process for obtaining it and uses thereof
CN111529506B (zh) * 2020-05-18 2021-09-03 同济大学 一种两性霉素b白蛋白纳米制剂及其制备方法和应用
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
KR102435211B1 (ko) * 2021-06-29 2022-08-23 (주)진셀바이오텍 알부민을 고효율로 생산하는 식물 세포주 및 이의 용도
CN114544926A (zh) * 2021-12-02 2022-05-27 浙江鑫科医疗科技有限公司 一种血清蛋白稳定剂
CN115236216B (zh) * 2022-06-07 2024-03-01 合肥和合医疗科技有限公司 高效液相色谱串联质谱检测全血中免疫抑制剂的试剂盒,其制备方法和检测方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58216126A (ja) 1982-06-11 1983-12-15 Ono Pharmaceut Co Ltd 可容化製剤
DE3702105A1 (de) 1987-01-24 1988-08-04 Bayer Ag Parenterale loesung
EP0326618A1 (en) 1987-03-04 1989-08-09 Nippon Hypox Laboratories Incorporated Medicinal composition containing albumin as carrier and process for its preparation
US5560933A (en) 1993-02-22 1996-10-01 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5621001A (en) 1992-08-03 1997-04-15 Bristol-Myers Squibb Company Methods for administration of taxol

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4833013A (sr) * 1971-08-30 1973-05-07
DE2653534C2 (de) * 1975-12-22 1986-08-28 Baxter Travenol Laboratories, Inc., Deerfield, Ill. Feste Antihämophilen-Faktor-Präparation und Verfahren zu ihrer Herstellung
JPS63215640A (ja) * 1987-03-04 1988-09-08 Nippon Hai Potsukusu:Kk 易吸収性抗炎症剤及びその製造方法
US5356927A (en) * 1992-12-02 1994-10-18 Thomas Jefferson University Methods of treating plasmodium and babesia parasitic infections
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
GB9510716D0 (en) * 1995-05-26 1995-07-19 Pharmacia Spa Substituted camptothecin derivatives and process for their preparation
TR199600775A2 (tr) 1996-09-27 1997-09-21 Tureks Turunc Madencilik Ic Ve Taslara eskitilmis görüntü kazandirilmasi icin bir yöntem.
US5776912A (en) * 1996-12-20 1998-07-07 Schering Corporation Lipophilic oligosaccharide antibiotic compositions
HUP9701554D0 (en) * 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins
ITMI20001107A1 (it) * 2000-05-18 2001-11-18 Acs Dobfar Spa Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58216126A (ja) 1982-06-11 1983-12-15 Ono Pharmaceut Co Ltd 可容化製剤
DE3702105A1 (de) 1987-01-24 1988-08-04 Bayer Ag Parenterale loesung
EP0326618A1 (en) 1987-03-04 1989-08-09 Nippon Hypox Laboratories Incorporated Medicinal composition containing albumin as carrier and process for its preparation
US5621001A (en) 1992-08-03 1997-04-15 Bristol-Myers Squibb Company Methods for administration of taxol
US5665761A (en) 1992-08-03 1997-09-09 Bristol-Myers Squibb Company Methods for administration of taxol
US5670537A (en) 1992-08-03 1997-09-23 Bristol-Meyers Squibb Company Method for effecting tumor regression with a low dose, short infusion taxol regimen
US5560933A (en) 1993-02-22 1996-10-01 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
EISEMAN, J.L. ET AL.: "Plasma pharmacokinetics and tissue distribution of Paclitaxel in CD2F1Mice", CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1994, pages 465 - 471
JOHANSEN K ET AL.: "Automated analysis of free and total concentrations of three antiepileptic drugs in plasma with on-line dialysis and high-performance liquid chromatography", J CHROMATOGR B BIOMED APPL., 1995, pages 292 - 298
PAVAN I ET AL.: "Monitoring propofol serum levels by rapid and sensitive reversed-phase high-performance liquid chromatography during prolonged sedation in ICU patients", J CHROMATOGR SCI., 1992, pages 164 - 166
ROWINSKY EK, CAZENAVE LA, DONEHOWER RC.: "Taxol: a novel investigational antimicrotubule agent", J NATL CANCER INST., 1990, pages 1247 - 1259, XP002054343, DOI: doi:10.1093/jnci/82.15.1247
THOMAS FT, TEPPER MA, THOMAS JM, HAISCH CE.: "15-Deoxyspergualin: a novel immunosuppressive drug with clinical potential", ANN. N. Y. ACAD. SCI., 1993, pages 175 - 192

Also Published As

Publication number Publication date
SI20189A (sl) 2000-10-31
HUP9701554D0 (en) 1997-11-28
CA2269923C (en) 2003-07-22
US20070232536A1 (en) 2007-10-04
TWI222365B (en) 2004-10-21
AR017120A1 (es) 2001-08-22
DK0981375T3 (da) 2003-05-05
US6743826B1 (en) 2004-06-01
HRP980499A2 (en) 1999-12-31
SK3292000A3 (en) 2000-08-14
BG104245A (en) 2000-11-30
US7119124B2 (en) 2006-10-10
EP0981375A1 (en) 2000-03-01
DE69810612D1 (de) 2003-02-13
WO1999013914A1 (en) 1999-03-25
CN1189216C (zh) 2005-02-16
CZ2000952A3 (cs) 2000-09-13
CA2269923A1 (en) 1999-03-25
BR9812469A (pt) 2002-02-05
LV12493B (en) 2001-01-20
SK284683B6 (sk) 2005-09-08
RO118695B1 (ro) 2003-09-30
LT2000018A (en) 2000-08-25
PT981375E (pt) 2003-04-30
CZ301326B6 (cs) 2010-01-20
PL193067B1 (pl) 2007-01-31
CN1270529A (zh) 2000-10-18
ATE230611T1 (de) 2003-01-15
KR100587962B1 (ko) 2006-06-13
NO20001371D0 (no) 2000-03-16
IL135055A (en) 2004-09-27
RS50102B (sr) 2009-01-22
PL339369A1 (en) 2000-12-18
AU9362398A (en) 1999-04-05
AU734695B2 (en) 2001-06-21
US20100076008A1 (en) 2010-03-25
US20040014655A1 (en) 2004-01-22
BG64749B1 (bg) 2006-02-28
NZ503302A (en) 2001-08-31
JP2001508806A (ja) 2001-07-03
ES2187062T3 (es) 2003-05-16
LV12493A (en) 2000-06-20
EP0981375B1 (en) 2003-01-08
NO325294B1 (no) 2008-03-17
EA004700B1 (ru) 2004-06-24
IL135055A0 (en) 2001-05-20
KR20010052072A (ko) 2001-06-25
DE69810612T2 (de) 2003-10-02
SI20189B (sl) 2007-10-31
US20050064028A1 (en) 2005-03-24
EA200000331A1 (ru) 2000-10-30
NO20001371L (no) 2000-05-18
US7501455B2 (en) 2009-03-10
TR200001545T2 (tr) 2000-10-23
US8946167B2 (en) 2015-02-03
YU16600A (sh) 2003-08-29
ZA988585B (en) 2000-03-13

Similar Documents

Publication Publication Date Title
LT4736B (lt) Farmacinės kompozicijos, turinčios plazmos proteino
CN1761485B (zh) 含略微水溶性抗癌剂和新型嵌段共聚物的胶束制剂
JP2003534265A (ja) 生物学的に活性な親水性化合物を非経口的に投与するための徐放性薬剤組成物
CN110354073B (zh) 一种免疫抑制剂单克隆抗体的液体制剂
BG65976B1 (bg) Фармацевтична форма на пептиди, методи за нейното получаване и приложение
Janáky et al. Short-chain analogs of luteinizing hormone-releasing hormone containing cytotoxic moieties.
WO2017191843A1 (ja) 高分子化薬物含有医薬組成物
EP1701699B1 (en) Pharmaceutical compositions of an A2a receptor antagonist
Neuhofer Development of lipid based depot formulations using interferon-beta-1b as a model protein
Barthomeuf et al. Stabilization of Octastatin®, a somatostatin analogue: comparative accelerated stability studies of two formulations for freeze-dried products
HU223974B1 (hu) Plazma protein tartalmú gyógyszerkészítmények és eljárás előállításukra
MXPA00002561A (en) Pharmaceutical compositions containing plasma protein

Legal Events

Date Code Title Description
PC9A Transfer of patents

Owner name: TEVA PHARMACEUTICAL WORKS PLC, HU

Effective date: 20060620

MK9A Expiry of a patent

Effective date: 20180917