LT3912B - Novel 16,17-acetal-substituted derivatives of pregnan-21-oic acid, process for preparing thereof, pharmaceutical preparations containing them - Google Patents

Novel 16,17-acetal-substituted derivatives of pregnan-21-oic acid, process for preparing thereof, pharmaceutical preparations containing them Download PDF

Info

Publication number
LT3912B
LT3912B LTIP1682A LTIP1682A LT3912B LT 3912 B LT3912 B LT 3912B LT IP1682 A LTIP1682 A LT IP1682A LT IP1682 A LTIP1682 A LT IP1682A LT 3912 B LT3912 B LT 3912B
Authority
LT
Lithuania
Prior art keywords
formula
compound
compound according
acid
alcohol
Prior art date
Application number
LTIP1682A
Other languages
English (en)
Lithuanian (lt)
Inventor
Paul Haakan Andersson
Per Ture Andersson
Bengt Ingemar Axelsson
Ralph Lennart Brattsand
Bror Arne Thalen
Jan William Trofast
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of LTIP1682A publication Critical patent/LTIP1682A/xx
Publication of LT3912B publication Critical patent/LT3912B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
LTIP1682A 1985-12-19 1993-12-28 Novel 16,17-acetal-substituted derivatives of pregnan-21-oic acid, process for preparing thereof, pharmaceutical preparations containing them LT3912B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8506015A SE8506015D0 (sv) 1985-12-19 1985-12-19 Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives

Publications (2)

Publication Number Publication Date
LTIP1682A LTIP1682A (en) 1995-07-25
LT3912B true LT3912B (en) 1996-04-25

Family

ID=20362521

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1682A LT3912B (en) 1985-12-19 1993-12-28 Novel 16,17-acetal-substituted derivatives of pregnan-21-oic acid, process for preparing thereof, pharmaceutical preparations containing them

Country Status (31)

Country Link
EP (1) EP0232690B1 (no)
JP (1) JPH0780900B2 (no)
KR (1) KR940004067B1 (no)
CN (1) CN1016508B (no)
AR (1) AR242797A1 (no)
AT (1) ATE57935T1 (no)
AU (1) AU591950B2 (no)
CA (1) CA1318664C (no)
CS (1) CS266597B2 (no)
DD (1) DD256703A5 (no)
DE (1) DE3675378D1 (no)
DK (1) DK168601B1 (no)
ES (1) ES2018656B3 (no)
FI (1) FI84488C (no)
GR (1) GR3001052T3 (no)
HU (1) HU196831B (no)
IE (1) IE59241B1 (no)
IL (1) IL80679A (no)
IS (1) IS1559B (no)
JO (1) JO1499B1 (no)
LT (1) LT3912B (no)
LV (1) LV10959B (no)
MY (1) MY100750A (no)
NO (1) NO164243C (no)
NZ (1) NZ218614A (no)
PH (1) PH23237A (no)
PL (1) PL151627B1 (no)
PT (1) PT83984B (no)
RU (1) RU1839673C (no)
SE (1) SE8506015D0 (no)
ZA (1) ZA868750B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203769B (en) * 1989-03-09 1991-09-30 Richter Gedeon Vegyeszet Process for producing new steroide derivatives and pharmaceutical compositions containing them
SE8903914D0 (sv) 1989-11-22 1989-11-22 Draco Ab Oral composition for the treatment of inflammatory bowel diseases
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
US6166024A (en) * 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD95565B1 (de) * 1971-10-04 1986-10-29 Schering Ag Verfahren zur herstellung neuer pregnansaeurederivate
DE2150268C3 (de) * 1971-10-04 1980-11-06 Schering Ag, 1000 Berlin Und 4619 Bergkamen Pregnansäure-Derivate, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE2204360C2 (de) * 1972-01-27 1982-11-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue Pregnansäure-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
SE378109B (no) * 1972-05-19 1975-08-18 Bofors Ab
DK135380C (da) * 1972-12-22 1977-10-03 Schering Ag Analogifremgangsmade til fremstilling af pregnan-21-syrederivater
DE2264003C2 (de) * 1972-12-22 1982-11-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue Pregnansäure-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
SE8403905D0 (sv) * 1984-07-30 1984-07-30 Draco Ab Liposomes and steroid esters

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TOOGOOD JH ET AL.: "Influence of dosing frequency and schedule on the response of chronic asthmatics to the aerosol steroid, budesonide.", J ALLERGY CLIN IMMUNOL., 1982, pages 288 - 298

Also Published As

Publication number Publication date
DD256703A5 (de) 1988-05-18
FI865128A0 (fi) 1986-12-16
CN1016508B (zh) 1992-05-06
NO164243B (no) 1990-06-05
CA1318664C (en) 1993-06-01
LV10959B (en) 1996-06-20
PT83984A (en) 1987-01-01
JPS62155296A (ja) 1987-07-10
LV10959A (lv) 1995-12-20
IL80679A0 (en) 1987-02-27
CN86108634A (zh) 1987-07-22
PL263041A1 (en) 1988-07-21
JO1499B1 (en) 1988-03-10
NZ218614A (en) 1989-02-24
IE863245L (en) 1987-06-19
ZA868750B (en) 1987-08-26
PH23237A (en) 1989-06-06
GR3001052T3 (en) 1992-03-20
FI84488B (fi) 1991-08-30
SE8506015D0 (sv) 1985-12-19
DK605186D0 (da) 1986-12-16
DK168601B1 (da) 1994-05-02
ES2018656B3 (es) 1991-05-01
PL151627B1 (en) 1990-09-28
PT83984B (pt) 1989-07-31
NO164243C (no) 1990-09-19
ATE57935T1 (de) 1990-11-15
CS266597B2 (en) 1990-01-12
DK605186A (da) 1987-06-20
RU1839673C (ru) 1993-12-30
CS960486A2 (en) 1989-04-14
KR940004067B1 (ko) 1994-05-11
IS3179A7 (is) 1987-06-20
LTIP1682A (en) 1995-07-25
AR242797A1 (es) 1993-05-31
FI84488C (fi) 1991-12-10
FI865128A (fi) 1987-06-20
HU196831B (en) 1989-01-30
HUT44273A (en) 1988-02-29
MY100750A (en) 1991-02-14
JPH0780900B2 (ja) 1995-08-30
KR870006081A (ko) 1987-07-09
NO865004L (no) 1987-06-22
EP0232690B1 (en) 1990-10-31
AU591950B2 (en) 1989-12-21
IE59241B1 (en) 1994-01-26
DE3675378D1 (de) 1990-12-06
NO865004D0 (no) 1986-12-11
IS1559B (is) 1994-10-05
IL80679A (en) 1992-03-29
EP0232690A1 (en) 1987-08-19
AU6644886A (en) 1987-06-25

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Effective date: 19971228