LT3600B - Nucleic acid fragment which codes for human proapolipoprotein a-i - Google Patents

Nucleic acid fragment which codes for human proapolipoprotein a-i Download PDF

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Publication number
LT3600B
LT3600B LTIP828A LTIP828A LT3600B LT 3600 B LT3600 B LT 3600B LT IP828 A LTIP828 A LT IP828A LT IP828 A LTIP828 A LT IP828A LT 3600 B LT3600 B LT 3600B
Authority
LT
Lithuania
Prior art keywords
sequence
human
dna sequence
proapo
dna
Prior art date
Application number
LTIP828A
Other languages
English (en)
Lithuanian (lt)
Inventor
Alex Bollen
Jean Gobert
Ernst Wuelfert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of LTIP828A publication Critical patent/LTIP828A/xx
Publication of LT3600B publication Critical patent/LT3600B/lt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP828A 1987-05-28 1993-08-03 Nucleic acid fragment which codes for human proapolipoprotein a-i LT3600B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712540A GB8712540D0 (en) 1987-05-28 1987-05-28 Expression of human proapolipoprotein a-i

Publications (2)

Publication Number Publication Date
LTIP828A LTIP828A (en) 1995-02-27
LT3600B true LT3600B (en) 1995-12-27

Family

ID=10618034

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP828A LT3600B (en) 1987-05-28 1993-08-03 Nucleic acid fragment which codes for human proapolipoprotein a-i

Country Status (33)

Country Link
US (1) US5059528A (xx)
EP (1) EP0293357B1 (xx)
JP (1) JP2634193B2 (xx)
KR (1) KR970000808B1 (xx)
CN (1) CN1031892C (xx)
AT (1) ATE89006T1 (xx)
AU (1) AU615654B2 (xx)
CA (1) CA1323851C (xx)
CY (1) CY1809A (xx)
CZ (1) CZ283648B6 (xx)
DD (1) DD291093A5 (xx)
DE (1) DE3880739T2 (xx)
DK (1) DK175686B1 (xx)
EG (1) EG19101A (xx)
ES (1) ES2054878T3 (xx)
FI (1) FI100056B (xx)
GB (1) GB8712540D0 (xx)
HK (1) HK137794A (xx)
HU (1) HU204562B (xx)
IE (1) IE62422B1 (xx)
IL (1) IL86480A (xx)
LT (1) LT3600B (xx)
LV (1) LV5288A3 (xx)
NO (1) NO179253C (xx)
NZ (1) NZ224808A (xx)
PL (1) PL158064B1 (xx)
PT (1) PT87562B (xx)
RU (1) RU2009198C1 (xx)
SG (1) SG131594G (xx)
SK (1) SK279166B6 (xx)
SU (1) SU1834904A3 (xx)
UA (1) UA19765A (xx)
ZA (1) ZA883824B (xx)

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JP2606228B2 (ja) * 1987-09-18 1997-04-30 三菱化学株式会社 ヒトプロアポリポプロテインa−i様蛋白の産生法
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US5846799A (en) * 1988-06-14 1998-12-08 La Region Wallone Human myeloperoxidase and its therapeutic application
US5460961A (en) * 1988-06-14 1995-10-24 La Region Wallonne Human myeloperoxidase and its therapeutic application
IT1229996B (it) * 1989-04-20 1991-09-20 Cesare Sirtori Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine.
WO1992009698A1 (en) * 1990-11-26 1992-06-11 Genetics Institute, Inc. Expression of pace in host cells and methods of use thereof
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
ATE132269T1 (de) * 1990-11-30 1996-01-15 Monoclonetics Int Verfahren zur diagnose chronischer niedriger rückenschmerzen und nackenschmerzen
SE9500778D0 (sv) 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
SE9603068D0 (sv) * 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603304D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a compound
KR100330355B1 (ko) * 1999-06-04 2002-04-01 장인순 회전유동발생 날개를 가진 덕트형 핵연료 집합체 지지격자
US20040047853A1 (en) * 2000-06-09 2004-03-11 Dahl Soren W Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
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KR100560102B1 (ko) * 2004-06-25 2006-03-13 한국생명공학연구원 프로아포리포단백질 a-ⅰ 변이체와, 이를 포함하는고지혈증 또는 동맥경화증 예방 및 치료제
US7427662B2 (en) * 2005-02-01 2008-09-23 Baord Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein
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CA2619943A1 (en) * 2005-08-26 2007-03-01 Cerenis Therapeutics Holding Sa Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria
US20080293102A1 (en) * 2007-02-28 2008-11-27 Cerenis Therapeutics Holding, S.A. Compositions and methods for producing apolipoprotein
CN102239260B (zh) * 2008-10-03 2017-04-12 库尔纳公司 通过抑制针对载脂蛋白‑a1的天然反义转录物治疗载脂蛋白‑a1相关疾病
MX359674B (es) 2008-11-10 2018-10-05 Alnylam Pharmaceuticals Inc Lipidos y composiciones novedosas para el suministro de terapeuticos.
AU2010208035B2 (en) 2009-01-29 2016-06-23 Arbutus Biopharma Corporation Improved lipid formulation for the delivery of nucleic acids
CN104922699B (zh) 2009-03-12 2020-07-24 阿尔尼拉姆医药品有限公司 脂质配制的组合物以及用于抑制Eg5和VEGF基因表达的方法
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CN103223177B (zh) 2009-05-06 2016-08-10 库尔纳公司 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病
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JPS6198998A (ja) 1984-10-18 1986-05-17 Matsushita Electric Ind Co Ltd 電動送風機
EP0186643A1 (fr) 1984-11-23 1986-07-02 Région Wallonne représentée par l'Exécutif Régional Wallon Procédé de préparation de plasmides vecteurs capables de transformer un hôte bactérien Escherichia coli et d'y promouvoir et contrôler l'expression d'un ADN hétérologue
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JPS6198998A (ja) 1984-10-18 1986-05-17 Matsushita Electric Ind Co Ltd 電動送風機
EP0186643A1 (fr) 1984-11-23 1986-07-02 Région Wallonne représentée par l'Exécutif Régional Wallon Procédé de préparation de plasmides vecteurs capables de transformer un hôte bactérien Escherichia coli et d'y promouvoir et contrôler l'expression d'un ADN hétérologue
WO1986004920A1 (en) 1985-02-13 1986-08-28 Biotechnology Research Partners, Limited Human metallothionein-ii promoter in mammalian expression system
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LORENZETTI R ET AL.: "Expression of the human apolipoprotein AI gene fused to the E. coli gene for beta-galactosidase", FEBS LETT., 1986, pages 343 - 346
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Also Published As

Publication number Publication date
CN88103118A (zh) 1988-12-14
DE3880739T2 (de) 1993-08-19
HU204562B (en) 1992-01-28
LV5288A3 (lv) 1993-10-10
CZ363888A3 (cs) 1998-02-18
NO882341D0 (no) 1988-05-27
EP0293357A1 (fr) 1988-11-30
SK363888A3 (en) 1998-07-08
PL158064B1 (pl) 1992-07-31
SK279166B6 (sk) 1998-07-08
JP2634193B2 (ja) 1997-07-23
CY1809A (en) 1995-10-20
KR880014110A (ko) 1988-12-22
DK289688A (da) 1988-11-29
PT87562B (pt) 1992-09-30
DE3880739D1 (de) 1993-06-09
DK175686B1 (da) 2005-01-17
PL272698A1 (en) 1989-03-06
AU1672388A (en) 1988-12-01
FI882456A (fi) 1988-11-29
CZ283648B6 (cs) 1998-05-13
FI100056B (fi) 1997-09-15
CA1323851C (en) 1993-11-02
DK289688D0 (da) 1988-05-27
GB8712540D0 (en) 1987-07-01
HK137794A (en) 1994-12-16
LTIP828A (en) 1995-02-27
NO882341L (no) 1988-11-29
IL86480A (en) 1992-08-18
CN1031892C (zh) 1996-05-29
EP0293357B1 (fr) 1993-05-05
AU615654B2 (en) 1991-10-10
IL86480A0 (en) 1988-11-15
NO179253B (no) 1996-05-28
NO179253C (no) 1996-09-04
NZ224808A (en) 1990-01-29
ES2054878T3 (es) 1994-08-16
IE62422B1 (en) 1995-02-08
IE881597L (en) 1988-11-28
HUT47153A (en) 1989-01-30
KR970000808B1 (en) 1997-01-20
PT87562A (pt) 1989-05-31
SU1834904A3 (ru) 1993-08-15
JPS6416589A (en) 1989-01-20
US5059528A (en) 1991-10-22
DD291093A5 (de) 1991-06-20
FI882456A0 (fi) 1988-05-25
SG131594G (en) 1995-01-13
ATE89006T1 (de) 1993-05-15
ZA883824B (en) 1989-02-22
UA19765A (uk) 1997-12-25
EG19101A (en) 1994-09-29
RU2009198C1 (ru) 1994-03-15

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