LT3600B - Nucleic acid fragment which codes for human proapolipoprotein a-i - Google Patents

Nucleic acid fragment which codes for human proapolipoprotein a-i Download PDF

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Publication number
LT3600B
LT3600B LTIP828A LTIP828A LT3600B LT 3600 B LT3600 B LT 3600B LT IP828 A LTIP828 A LT IP828A LT IP828 A LTIP828 A LT IP828A LT 3600 B LT3600 B LT 3600B
Authority
LT
Lithuania
Prior art keywords
sequence
human
dna sequence
proapo
dna
Prior art date
Application number
LTIP828A
Other languages
English (en)
Lithuanian (lt)
Inventor
Alex Bollen
Jean Gobert
Ernst Wuelfert
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of LTIP828A publication Critical patent/LTIP828A/xx
Publication of LT3600B publication Critical patent/LT3600B/lt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP828A 1987-05-28 1993-08-03 Nucleic acid fragment which codes for human proapolipoprotein a-i LT3600B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878712540A GB8712540D0 (en) 1987-05-28 1987-05-28 Expression of human proapolipoprotein a-i

Publications (2)

Publication Number Publication Date
LTIP828A LTIP828A (en) 1995-02-27
LT3600B true LT3600B (en) 1995-12-27

Family

ID=10618034

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP828A LT3600B (en) 1987-05-28 1993-08-03 Nucleic acid fragment which codes for human proapolipoprotein a-i

Country Status (33)

Country Link
US (1) US5059528A (de)
EP (1) EP0293357B1 (de)
JP (1) JP2634193B2 (de)
KR (1) KR970000808B1 (de)
CN (1) CN1031892C (de)
AT (1) ATE89006T1 (de)
AU (1) AU615654B2 (de)
CA (1) CA1323851C (de)
CY (1) CY1809A (de)
CZ (1) CZ283648B6 (de)
DD (1) DD291093A5 (de)
DE (1) DE3880739T2 (de)
DK (1) DK175686B1 (de)
EG (1) EG19101A (de)
ES (1) ES2054878T3 (de)
FI (1) FI100056B (de)
GB (1) GB8712540D0 (de)
HK (1) HK137794A (de)
HU (1) HU204562B (de)
IE (1) IE62422B1 (de)
IL (1) IL86480A (de)
LT (1) LT3600B (de)
LV (1) LV5288A3 (de)
NO (1) NO179253C (de)
NZ (1) NZ224808A (de)
PL (1) PL158064B1 (de)
PT (1) PT87562B (de)
RU (1) RU2009198C1 (de)
SG (1) SG131594G (de)
SK (1) SK363888A3 (de)
SU (1) SU1834904A3 (de)
UA (1) UA19765A (de)
ZA (1) ZA883824B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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AU587989B2 (en) * 1984-10-16 1989-09-07 Mitsubishi Chemical Corporation DMA fragments, expression vectors, proteins, hosts, and process for production of the proteins
JP2606228B2 (ja) * 1987-09-18 1997-04-30 三菱化学株式会社 ヒトプロアポリポプロテインａ−ｉ様蛋白の産生法
DE68917379T2 (de) * 1988-05-31 1994-12-01 Mitsubishi Chem Ind Verfahren zur Herstellung von Proteinen, die ähnlich dem natürlich-menschlichen Apolipoprotein-E sind.
US5846799A (en) * 1988-06-14 1998-12-08 La Region Wallone Human myeloperoxidase and its therapeutic application
US5460961A (en) * 1988-06-14 1995-10-24 La Region Wallonne Human myeloperoxidase and its therapeutic application
IT1229996B (it) * 1989-04-20 1991-09-20 Cesare Sirtori Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine.
JP4236698B2 (ja) * 1990-11-26 2009-03-11 ジェネティックス インスティチュート，リミテッド ライアビリティ カンパニー 宿主細胞でのｐａｃｅの発現およびその使用法
DK0559795T3 (da) * 1990-11-30 1996-01-29 Monoclonetics Int Fremgangsmåder til diagnosticering af kroniske smerter i lænderegionen og halshvrivelsøjlen
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
SE9500778D0 (sv) * 1995-03-03 1995-03-03 Pharmacia Ab Process for producing a protein
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
SE9603068D0 (sv) * 1996-08-23 1996-08-23 Pharmacia & Upjohn Ab Process for purifying a protein
SE9603304D0 (sv) * 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a compound
SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
KR100330355B1 (ko) * 1999-06-04 2002-04-01 장인순 회전유동발생 날개를 가진 덕트형 핵연료 집합체 지지격자
US20040047853A1 (en) * 2000-06-09 2004-03-11 Dahl Soren W Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
JP2004530417A (ja) * 2000-12-12 2004-10-07 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
KR100560102B1 (ko) * 2004-06-25 2006-03-13 한국생명공학연구원 프로아포리포단백질 ａ－ⅰ 변이체와, 이를 포함하는고지혈증 또는 동맥경화증 예방 및 치료제
US7427662B2 (en) * 2005-02-01 2008-09-23 Baord Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein
US8206750B2 (en) 2005-03-24 2012-06-26 Cerenis Therapeutics Holding S.A. Charged lipoprotein complexes and their uses
EP1917278A2 (de) * 2005-08-26 2008-05-07 Cerenis Therapeutics Holding SA Zusammensetzungen und verfahren für die herstellung von apolipoprotein gene produkten in lactic acid bakterien
US20080293102A1 (en) * 2007-02-28 2008-11-27 Cerenis Therapeutics Holding, S.A. Compositions and methods for producing apolipoprotein
JP6128732B2 (ja) * 2008-10-03 2017-05-17 クルナ・インコーポレーテッド アポリポタンパク質−ａ１に対する天然アンチセンス転写物の抑制によるアポリポタンパク質−ａ１関連疾患の治療
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Citations (4)

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JPS6198998A (ja) 1984-10-18 1986-05-17 Matsushita Electric Ind Co Ltd 電動送風機
EP0186643A1 (de) 1984-11-23 1986-07-02 Région Wallonne représentée par l'Exécutif Régional Wallon Verfahren zur Herstellung von Vektorplasmiden, fähig zur Transformation von Escherichia coli-Wirtebakterien und zur Förderung und Kontrolle der Expression eines DNA-Heterologen
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WO1987002062A1 (en) 1985-10-04 1987-04-09 Biotechnology Research Partners, Ltd. Recombinant apolipoproteins and methods

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GB8507833D0 (en) * 1985-03-26 1985-05-01 Biogen Nv Production of human somatomedin c
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EP0269260A3 (de) * 1986-10-29 1988-06-22 Biotechnology Research Partners, Ltd. ApoAI-C-III-AIV, apoAII, apoB, apoCI und LDL-Rezeptor-Polymorphismus für genetischen Fingerabdruck und Atherosklerosevorhersage

Patent Citations (4)

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JPS6198998A (ja) 1984-10-18 1986-05-17 Matsushita Electric Ind Co Ltd 電動送風機
EP0186643A1 (de) 1984-11-23 1986-07-02 Région Wallonne représentée par l'Exécutif Régional Wallon Verfahren zur Herstellung von Vektorplasmiden, fähig zur Transformation von Escherichia coli-Wirtebakterien und zur Förderung und Kontrolle der Expression eines DNA-Heterologen
WO1986004920A1 (en) 1985-02-13 1986-08-28 Biotechnology Research Partners, Limited Human metallothionein-ii promoter in mammalian expression system
WO1987002062A1 (en) 1985-10-04 1987-04-09 Biotechnology Research Partners, Ltd. Recombinant apolipoproteins and methods

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BREWER HB JR: "The amino acid sequence of human APOA-I, an apolipoprotein isolated from high density lipoproteins", BIOCHEM BIOPHYS RES COMMUN., 1978, pages 623 - 630, XP024839665, DOI: doi:10.1016/0006-291X(78)91614-5
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LORENZETTI R ET AL.: "Expression of the human apolipoprotein AI gene fused to the E. coli gene for beta-galactosidase", FEBS LETT., 1986, pages 343 - 346
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Also Published As

Publication number Publication date
DE3880739D1 (de) 1993-06-09
EP0293357B1 (de) 1993-05-05
FI882456A0 (fi) 1988-05-25
SK279166B6 (sk) 1998-07-08
SG131594G (en) 1995-01-13
HU204562B (en) 1992-01-28
ATE89006T1 (de) 1993-05-15
FI100056B (fi) 1997-09-15
LV5288A3 (lv) 1993-10-10
NO882341D0 (no) 1988-05-27
CY1809A (en) 1995-10-20
LTIP828A (en) 1995-02-27
DD291093A5 (de) 1991-06-20
CZ283648B6 (cs) 1998-05-13
NZ224808A (en) 1990-01-29
EP0293357A1 (de) 1988-11-30
IL86480A0 (en) 1988-11-15
JPS6416589A (en) 1989-01-20
DK289688A (da) 1988-11-29
ZA883824B (en) 1989-02-22
PT87562A (pt) 1989-05-31
RU2009198C1 (ru) 1994-03-15
DE3880739T2 (de) 1993-08-19
CZ363888A3 (cs) 1998-02-18
HUT47153A (en) 1989-01-30
CN1031892C (zh) 1996-05-29
PL272698A1 (en) 1989-03-06
FI882456A (fi) 1988-11-29
US5059528A (en) 1991-10-22
CA1323851C (en) 1993-11-02
IL86480A (en) 1992-08-18
JP2634193B2 (ja) 1997-07-23
UA19765A (uk) 1997-12-25
ES2054878T3 (es) 1994-08-16
HK137794A (en) 1994-12-16
IE62422B1 (en) 1995-02-08
KR880014110A (ko) 1988-12-22
CN88103118A (zh) 1988-12-14
NO882341L (no) 1988-11-29
PT87562B (pt) 1992-09-30
DK175686B1 (da) 2005-01-17
IE881597L (en) 1988-11-28
AU615654B2 (en) 1991-10-10
SK363888A3 (en) 1998-07-08
AU1672388A (en) 1988-12-01
SU1834904A3 (ru) 1993-08-15
EG19101A (en) 1994-09-29
DK289688D0 (da) 1988-05-27
GB8712540D0 (en) 1987-07-01
KR970000808B1 (en) 1997-01-20
PL158064B1 (pl) 1992-07-31
NO179253C (no) 1996-09-04
NO179253B (no) 1996-05-28

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