LT3590942T - Hepatito b viruso paviršinio antigeno inhibitorius - Google Patents

Hepatito b viruso paviršinio antigeno inhibitorius

Info

Publication number
LT3590942T
LT3590942T LTEPPCT/CN2018/078581T LT18763490T LT3590942T LT 3590942 T LT3590942 T LT 3590942T LT 18763490 T LT18763490 T LT 18763490T LT 3590942 T LT3590942 T LT 3590942T
Authority
LT
Lithuania
Prior art keywords
hepatitis
surface antigen
virus surface
antigen inhibitor
inhibitor
Prior art date
Application number
LTEPPCT/CN2018/078581T
Other languages
English (en)
Inventor
Fei Sun
Jinhua Du
Yanbin Hu
Lili Zhou
Charles Z. Ding
Shuhhui CHEN
Original Assignee
Fujian Cosunter Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujian Cosunter Pharmaceutical Co., Ltd. filed Critical Fujian Cosunter Pharmaceutical Co., Ltd.
Publication of LT3590942T publication Critical patent/LT3590942T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTEPPCT/CN2018/078581T 2017-03-09 2018-03-09 Hepatito b viruso paviršinio antigeno inhibitorius LT3590942T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201710138275 2017-03-09
PCT/CN2018/078581 WO2018161960A1 (zh) 2017-03-09 2018-03-09 乙型肝炎病毒表面抗原抑制剂

Publications (1)

Publication Number Publication Date
LT3590942T true LT3590942T (lt) 2021-07-12

Family

ID=63447286

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/CN2018/078581T LT3590942T (lt) 2017-03-09 2018-03-09 Hepatito b viruso paviršinio antigeno inhibitorius

Country Status (25)

Country Link
US (1) US11008331B2 (lt)
EP (1) EP3590942B1 (lt)
JP (1) JP6783424B2 (lt)
KR (1) KR102087397B1 (lt)
CN (1) CN109071564B (lt)
AU (1) AU2018232071B2 (lt)
BR (1) BR112019018650B1 (lt)
CA (1) CA3055442C (lt)
DK (1) DK3590942T3 (lt)
EA (1) EA038122B9 (lt)
ES (1) ES2879930T3 (lt)
HR (1) HRP20211331T1 (lt)
HU (1) HUE055170T2 (lt)
IL (1) IL269142B (lt)
LT (1) LT3590942T (lt)
MX (1) MX2019010736A (lt)
MY (1) MY174224A (lt)
PH (1) PH12019502052A1 (lt)
PL (1) PL3590942T3 (lt)
PT (1) PT3590942T (lt)
RS (1) RS62094B1 (lt)
SG (1) SG11201908101YA (lt)
SI (1) SI3590942T1 (lt)
WO (1) WO2018161960A1 (lt)
ZA (1) ZA201906252B (lt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10738035B2 (en) 2015-05-13 2020-08-11 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US10179792B2 (en) 2016-03-07 2019-01-15 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
CN110066278B (zh) 2017-06-01 2021-06-08 广东东阳光药业有限公司 稠合三环类化合物及其在药物中的应用
BR112020004112A2 (pt) 2017-08-28 2020-09-24 Enanta Pharmaceuticals, Inc. agentes antiviras da hepatite b
US11058678B2 (en) 2018-01-22 2021-07-13 Enanta Pharmaceuticals, Inc. Substituted heterocycles as antiviral agents
WO2019169539A1 (en) * 2018-03-05 2019-09-12 Pharmaresources (Shanghai) Co., Ltd. Novel oxa-and aza-tricyclic 4-pyridone-3-carboxylic acid for treatment and prophylaxis of hepatitis b virus infection
US10729688B2 (en) 2018-03-29 2020-08-04 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US20210330678A1 (en) 2018-09-05 2021-10-28 Children`S Medical Center Corporation Papd5 inhibitors and methods of use thereof
UY38383A (es) 2018-09-21 2020-04-30 Enanta Pharm Inc Heterociclos funcionalizados como agentes antivirales
JP2022511378A (ja) 2018-09-30 2022-01-31 サンシャイン・レイク・ファーマ・カンパニー・リミテッド 縮合四環系化合物および医薬品におけるそれらの使用
EP3883570A4 (en) 2018-11-21 2022-07-13 Enanta Pharmaceuticals, Inc. FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS
US11236111B2 (en) 2019-06-03 2022-02-01 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US11472808B2 (en) 2019-06-04 2022-10-18 Enanta Pharmaceuticals, Inc. Substituted pyrrolo[1,2-c]pyrimidines as hepatitis B antiviral agents
US11760755B2 (en) 2019-06-04 2023-09-19 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US11738019B2 (en) 2019-07-11 2023-08-29 Enanta Pharmaceuticals, Inc. Substituted heterocycles as antiviral agents
WO2021055425A2 (en) 2019-09-17 2021-03-25 Enanta Pharmaceuticals, Inc. Functionalized heterocycles as antiviral agents
JP2022548746A (ja) * 2019-09-19 2022-11-21 福建▲広▼生中霖生物科技有限公司 B型肝炎表面抗原阻害剤の結晶形及びその使用
US11802125B2 (en) 2020-03-16 2023-10-31 Enanta Pharmaceuticals, Inc. Functionalized heterocyclic compounds as antiviral agents
WO2021228213A1 (zh) 2020-05-15 2021-11-18 福建广生堂药业股份有限公司 包含三并环类化合物的组合及其在制备治疗hbv药物中的应用
JP2023526345A (ja) * 2020-05-15 2023-06-21 福建▲広▼生中霖生物科技有限公司 B型肝炎の治療に使用される組み合わせ
CN116390920A (zh) * 2020-11-25 2023-07-04 豪夫迈·罗氏有限公司 用于治疗和预防乙型肝炎病毒感染的芳族螺环酰胺衍生物
WO2022152019A1 (zh) * 2021-01-15 2022-07-21 福建广生中霖生物科技有限公司 一种手性噁嗪类化合物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130251647A1 (en) 2011-09-20 2013-09-26 Basf Se Low molecular weight modulators of the cold menthol receptor trpm8 and use thereof
CN103450184A (zh) * 2012-05-29 2013-12-18 上海壹志医药科技有限公司 斯氏紫堇碱衍生物的盐
SG11201605970QA (en) 2014-01-30 2016-08-30 Hoffmann La Roche Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
EP3256471B1 (en) * 2015-02-11 2018-12-12 F. Hoffmann-La Roche AG Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
CN107849037B (zh) * 2015-07-21 2020-04-17 豪夫迈·罗氏有限公司 用于治疗和预防乙型肝炎病毒感染的三环4-吡啶酮-3-甲酸衍生物
WO2017017043A1 (en) * 2015-07-28 2017-02-02 F. Hoffmann-La Roche Ag Novel 6,7-dihydropyrido[2,1-a]phthalazin-2-ones for the treatment and prophylaxis of hepatitis b virus infection
CN107759585A (zh) * 2016-07-29 2018-03-06 银杏树药业(苏州)有限公司 一种异喹啉类化合物及其药用组合物和作为抗病毒药物的应用

Also Published As

Publication number Publication date
KR20190117799A (ko) 2019-10-16
US20200039995A1 (en) 2020-02-06
EA038122B1 (ru) 2021-07-09
CA3055442A1 (en) 2018-09-13
PL3590942T3 (pl) 2021-12-13
BR112019018650B1 (pt) 2021-12-14
PH12019502052A1 (en) 2020-07-06
EA201992082A1 (ru) 2020-02-12
CA3055442C (en) 2021-03-23
AU2018232071A1 (en) 2019-10-17
AU2018232071B2 (en) 2021-07-08
DK3590942T3 (da) 2021-09-06
ZA201906252B (en) 2021-04-28
BR112019018650A2 (pt) 2020-04-07
CN109071564A (zh) 2018-12-21
PT3590942T (pt) 2021-07-28
SG11201908101YA (en) 2019-10-30
MX2019010736A (es) 2019-11-05
EP3590942A1 (en) 2020-01-08
RS62094B1 (sr) 2021-08-31
HRP20211331T1 (hr) 2021-11-26
EP3590942B1 (en) 2021-06-09
JP2020509075A (ja) 2020-03-26
HUE055170T2 (hu) 2021-11-29
WO2018161960A1 (zh) 2018-09-13
CN109071564B (zh) 2019-08-27
EA038122B9 (ru) 2021-09-14
KR102087397B1 (ko) 2020-03-11
EP3590942A4 (en) 2020-01-08
SI3590942T1 (sl) 2021-11-30
US11008331B2 (en) 2021-05-18
IL269142B (en) 2020-07-30
ES2879930T3 (es) 2021-11-23
JP6783424B2 (ja) 2020-11-11
MY174224A (en) 2020-03-23

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