HUE055170T2 - Hepatitis-B vírus felszíni antigén inhibitor - Google Patents
Hepatitis-B vírus felszíni antigén inhibitorInfo
- Publication number
- HUE055170T2 HUE055170T2 HUE18763490A HUE18763490A HUE055170T2 HU E055170 T2 HUE055170 T2 HU E055170T2 HU E18763490 A HUE18763490 A HU E18763490A HU E18763490 A HUE18763490 A HU E18763490A HU E055170 T2 HUE055170 T2 HU E055170T2
- Authority
- HU
- Hungary
- Prior art keywords
- hepatitis
- surface antigen
- virus surface
- antigen inhibitor
- inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710138275 | 2017-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE055170T2 true HUE055170T2 (hu) | 2021-11-29 |
Family
ID=63447286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18763490A HUE055170T2 (hu) | 2017-03-09 | 2018-03-09 | Hepatitis-B vírus felszíni antigén inhibitor |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US11008331B2 (hu) |
| EP (1) | EP3590942B1 (hu) |
| JP (1) | JP6783424B2 (hu) |
| KR (1) | KR102087397B1 (hu) |
| CN (1) | CN109071564B (hu) |
| AU (1) | AU2018232071B2 (hu) |
| BR (1) | BR112019018650B1 (hu) |
| CA (1) | CA3055442C (hu) |
| DK (1) | DK3590942T3 (hu) |
| EA (1) | EA038122B9 (hu) |
| ES (1) | ES2879930T3 (hu) |
| HR (1) | HRP20211331T1 (hu) |
| HU (1) | HUE055170T2 (hu) |
| IL (1) | IL269142B (hu) |
| LT (1) | LT3590942T (hu) |
| MX (1) | MX2019010736A (hu) |
| MY (1) | MY174224A (hu) |
| PH (1) | PH12019502052A1 (hu) |
| PL (1) | PL3590942T3 (hu) |
| PT (1) | PT3590942T (hu) |
| RS (1) | RS62094B1 (hu) |
| SG (1) | SG11201908101YA (hu) |
| SI (1) | SI3590942T1 (hu) |
| WO (1) | WO2018161960A1 (hu) |
| ZA (1) | ZA201906252B (hu) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016183266A1 (en) | 2015-05-13 | 2016-11-17 | Enanta Pharmaceuticals, Inc. | Ehpatitis b antiviral agents |
| ES2938341T3 (es) | 2016-03-07 | 2023-04-10 | Enanta Pharm Inc | Agentes antivirales contra la hepatitis B |
| CN110066278B (zh) | 2017-06-01 | 2021-06-08 | 广东东阳光药业有限公司 | 稠合三环类化合物及其在药物中的应用 |
| WO2019046271A1 (en) | 2017-08-28 | 2019-03-07 | Enanta Pharmaceuticals, Inc. | ANTIVIRAL AGENTS AGAINST HEPATITIS B |
| WO2019143902A2 (en) | 2018-01-22 | 2019-07-25 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| WO2019169539A1 (en) * | 2018-03-05 | 2019-09-12 | Pharmaresources (Shanghai) Co., Ltd. | Novel oxa-and aza-tricyclic 4-pyridone-3-carboxylic acid for treatment and prophylaxis of hepatitis b virus infection |
| WO2019191166A1 (en) | 2018-03-29 | 2019-10-03 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
| CA3111792A1 (en) | 2018-09-05 | 2020-03-12 | Children's Medical Center Corporation | Papd5 inhibitors and methods of use thereof |
| MX2021003253A (es) | 2018-09-21 | 2021-08-11 | Enanta Pharm Inc | Heterociclos funcionalizados como agentes antivirales. |
| EP3856740A4 (en) | 2018-09-30 | 2021-12-15 | Sunshine Lake Pharma Co., Ltd. | CONDENSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE |
| AU2019385477A1 (en) | 2018-11-21 | 2021-06-10 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| WO2020247444A1 (en) | 2019-06-03 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
| WO2020247561A1 (en) | 2019-06-04 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
| WO2020247575A1 (en) | 2019-06-04 | 2020-12-10 | Enanta Pharmaceuticals, Inc. | Hepatitis b antiviral agents |
| WO2021007488A1 (en) | 2019-07-11 | 2021-01-14 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| US11236108B2 (en) | 2019-09-17 | 2022-02-01 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| US11807647B2 (en) | 2019-09-19 | 2023-11-07 | Fujian Akeylink Biotechnology Co., Ltd. | Crystal form of hepatitis B surface antigen inhibitor and application thereof |
| US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| CN115515595A (zh) * | 2020-05-15 | 2022-12-23 | 福建广生中霖生物科技有限公司 | 用于治疗乙肝的组合 |
| WO2021228213A1 (zh) | 2020-05-15 | 2021-11-18 | 福建广生堂药业股份有限公司 | 包含三并环类化合物的组合及其在制备治疗hbv药物中的应用 |
| EP4251621A1 (en) * | 2020-11-25 | 2023-10-04 | F. Hoffmann-La Roche AG | Aromatic spiro ring amide derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| CN116744932A (zh) * | 2021-01-15 | 2023-09-12 | 福建广生中霖生物科技有限公司 | 一种手性噁嗪类化合物的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130251647A1 (en) * | 2011-09-20 | 2013-09-26 | Basf Se | Low molecular weight modulators of the cold menthol receptor trpm8 and use thereof |
| CN103450184A (zh) * | 2012-05-29 | 2013-12-18 | 上海壹志医药科技有限公司 | 斯氏紫堇碱衍生物的盐 |
| WO2015113990A1 (en) | 2014-01-30 | 2015-08-06 | F. Hoffmann-La Roche Ag | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection |
| EP3256471B1 (en) * | 2015-02-11 | 2018-12-12 | F. Hoffmann-La Roche AG | Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| JP6598974B2 (ja) | 2015-07-21 | 2019-10-30 | エフ．ホフマン−ラ ロシュ アーゲー | Ｂ型肝炎ウイルス感染症の治療および予防のための新規な三環式４−ピリドン−３−カルボン酸誘導体 |
| WO2017017043A1 (en) | 2015-07-28 | 2017-02-02 | F. Hoffmann-La Roche Ag | Novel 6,7-dihydropyrido[2,1-a]phthalazin-2-ones for the treatment and prophylaxis of hepatitis b virus infection |
| CN107759585A (zh) * | 2016-07-29 | 2018-03-06 | 银杏树药业(苏州)有限公司 | 一种异喹啉类化合物及其药用组合物和作为抗病毒药物的应用 |
-
2018
- 2018-03-09 HU HUE18763490A patent/HUE055170T2/hu unknown
- 2018-03-09 PL PL18763490T patent/PL3590942T3/pl unknown
- 2018-03-09 WO PCT/CN2018/078581 patent/WO2018161960A1/zh unknown
- 2018-03-09 EA EA201992082A patent/EA038122B9/ru unknown
- 2018-03-09 PT PT187634902T patent/PT3590942T/pt unknown
- 2018-03-09 LT LTEPPCT/CN2018/078581T patent/LT3590942T/lt unknown
- 2018-03-09 DK DK18763490.2T patent/DK3590942T3/da active
- 2018-03-09 SG SG11201908101Y patent/SG11201908101YA/en unknown
- 2018-03-09 KR KR1020197029437A patent/KR102087397B1/ko active IP Right Grant
- 2018-03-09 MX MX2019010736A patent/MX2019010736A/es active IP Right Grant
- 2018-03-09 CN CN201880001647.2A patent/CN109071564B/zh active Active
- 2018-03-09 US US16/491,769 patent/US11008331B2/en active Active
- 2018-03-09 JP JP2019548977A patent/JP6783424B2/ja active Active
- 2018-03-09 BR BR112019018650-6A patent/BR112019018650B1/pt active IP Right Grant
- 2018-03-09 CA CA3055442A patent/CA3055442C/en active Active
- 2018-03-09 ES ES18763490T patent/ES2879930T3/es active Active
- 2018-03-09 SI SI201830376T patent/SI3590942T1/sl unknown
- 2018-03-09 MY MYPI2019005107A patent/MY174224A/en unknown
- 2018-03-09 AU AU2018232071A patent/AU2018232071B2/en active Active
- 2018-03-09 EP EP18763490.2A patent/EP3590942B1/en active Active
- 2018-03-09 RS RS20210851A patent/RS62094B1/sr unknown
-
2019
- 2019-09-05 IL IL269142A patent/IL269142B/en active IP Right Grant
- 2019-09-09 PH PH12019502052A patent/PH12019502052A1/en unknown
- 2019-09-20 ZA ZA2019/06252A patent/ZA201906252B/en unknown
-
2021
- 2021-08-18 HR HRP20211331TT patent/HRP20211331T1/hr unknown
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