LT3333B - Chromatographic separation of plasma protein and concentrates obtained by this method - Google Patents

Chromatographic separation of plasma protein and concentrates obtained by this method Download PDF

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Publication number
LT3333B
LT3333B LTIP262A LTIP262A LT3333B LT 3333 B LT3333 B LT 3333B LT IP262 A LTIP262 A LT IP262A LT IP262 A LTIP262 A LT IP262A LT 3333 B LT3333 B LT 3333B
Authority
LT
Lithuania
Prior art keywords
factor viii
factor
concentrate
plasma
buffer
Prior art date
Application number
LTIP262A
Other languages
English (en)
Lithuanian (lt)
Inventor
Thierry Burnouf
Miryana Burnouf
Original Assignee
Centre Regional De Transfusion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Centre Regional De Transfusion filed Critical Centre Regional De Transfusion
Publication of LTIP262A publication Critical patent/LTIP262A/xx
Publication of LT3333B publication Critical patent/LT3333B/lt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTIP262A 1988-06-07 1992-12-29 Chromatographic separation of plasma protein and concentrates obtained by this method LT3333B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807530A FR2632309B1 (fr) 1988-06-07 1988-06-07 Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus

Publications (2)

Publication Number Publication Date
LTIP262A LTIP262A (en) 1994-10-25
LT3333B true LT3333B (en) 1995-07-25

Family

ID=9367001

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP262A LT3333B (en) 1988-06-07 1992-12-29 Chromatographic separation of plasma protein and concentrates obtained by this method

Country Status (17)

Country Link
US (1) US5252709A (da)
EP (1) EP0359593B2 (da)
JP (1) JP2805364B2 (da)
KR (1) KR970010923B1 (da)
AT (1) ATE121750T1 (da)
AU (2) AU622436B2 (da)
CA (1) CA1340742C (da)
DE (2) DE359593T1 (da)
DK (1) DK175322B1 (da)
ES (1) ES2070919T5 (da)
FI (1) FI96210C (da)
FR (1) FR2632309B1 (da)
LT (1) LT3333B (da)
NO (1) NO177188C (da)
RU (1) RU1837880C (da)
UA (1) UA11061A (da)
WO (1) WO1989012065A1 (da)

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GB8729822D0 (en) * 1987-12-22 1988-02-03 Central Blood Lab Authority Chemical process
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US5760183A (en) * 1989-02-17 1998-06-02 Association D'aquitaine Pour De Developpment De La Transfusion Sanguine Et Des Recherches Hematologiques Process for the manufacture of very high-purity antithaemophilic factor (FVIIIC), and von Willebrand factor, and pharmaceutical compositions containing same
FR2644064B1 (fr) * 1989-02-17 1994-05-27 Aquitaine Dev Transf Sanguine Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
DE3926034C3 (de) * 1989-08-07 1996-11-21 Behringwerke Ag Verfahren zur Herstellung eines stabilen Faktors VIII
FR2651437A1 (fr) 1989-09-05 1991-03-08 Lille Transfusion Sanguine Procede de preparation de concentre du complexe facteur viii-facteur von willebrand de la coagulation sanguine a partir de plasma total.
NL9000090A (nl) * 1990-01-15 1991-08-01 Harimex Ligos Bv Werkwijze voor het bereiden van een fibrinogeenconcentraat uit bloedplasma, inrichting voor het uitvoeren van deze werkwijze en werkwijze voor het bereiden van fibrinogeen uit het concentraat.
FR2673632A1 (fr) * 1991-03-08 1992-09-11 Lille Transfusion Sanguine Procede de preparation de concentre de facteur von willebrand humain de tres haute purete, approprie a un usage therapeutique.
US5792835A (en) * 1991-09-05 1998-08-11 Baxter International Inc. Method of preparing a topical fibrinogen complex
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AT399818B (de) * 1992-04-24 1995-07-25 Immuno Ag Verfahren zur herstellung einer hochgereinigten virussicheren faktor viii-präparation
CA2195127C (en) * 1994-07-14 2007-06-19 Ruth Laub Concentrate of fibrinogene obtained from blood plasma, process and plant for its preparation
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
US6143179A (en) * 1996-06-24 2000-11-07 Kerckhoff-Klinik Gmbh Method for the affinity-chromatographic purification of factor VIII
US6037457A (en) * 1997-01-31 2000-03-14 The University Of North Carolina At Chapel Hill Method for recombinant fibrinogen production
AT405403B (de) 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
BR0008405B1 (pt) 1999-02-22 2014-04-22 Baxter Int Composição de fator viii formulada sem a adição de albumina, uso de uma composição de fator viii, e, método de liofilizar uma formulação farmacêutica aquosa
EP1148063A1 (de) * 2000-04-18 2001-10-24 Octapharma AG Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung
FR2857267B1 (fr) 2003-07-09 2006-03-10 Lab Francais Du Fractionnement Formulation stabilisante et solubilisante pour les proteines cryoprecipitables.
SG150501A1 (en) * 2004-02-05 2009-03-30 Millipore Corp Porous adsorptive or chromatographic media
DE102004009400A1 (de) 2004-02-24 2005-09-08 Zlb Behring Gmbh Fibrinogen Reinigung
FR2874216B1 (fr) 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
FR2885369B1 (fr) * 2005-05-04 2010-11-12 Lab Francais Du Fractionnement Materiel infectieux synthetique et standardise de type prion et ses utilisations en tant qu'inoculum infectant.
FR2887883B1 (fr) * 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
FR2920429B1 (fr) * 2007-08-30 2012-10-05 Lfb Biotechnologies Procede de purification du facteur viii et du facteur von willebrand
US20090130738A1 (en) * 2007-11-19 2009-05-21 Mikhail Kozlov Media for membrane ion exchange chromatography
WO2009145722A1 (en) * 2008-05-30 2009-12-03 Ge Healthcare Bio-Sciences Ab Separation method utilizing polyallylamine ligands
US8741846B2 (en) 2008-06-23 2014-06-03 Bio-Products & Bio-Engineering Ag Storage-stable, functionally intact fibrinogen
JP5779780B2 (ja) * 2008-11-07 2015-09-16 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated 第viii因子製剤
IT1396528B1 (it) 2009-01-19 2012-12-14 Kedrion Spa Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn).
PL2499165T3 (pl) 2009-11-13 2017-04-28 Grifols Therapeutics Inc. Preparaty zawierające czynnik von willenbranda (vwf) oraz sposoby, zestawy i zastosowania z nim powiązane
FR2952641B1 (fr) 2009-11-18 2012-01-13 Lfb Biomedicaments Procede de traitement du plasma sanguin comprenant une etape de lavage par dispersion
RU2012133474A (ru) 2010-01-18 2014-02-27 Ново Нордиск Хелс Кеа Аг Очистка факторов свертывания крови
RU2445974C2 (ru) * 2010-04-26 2012-03-27 Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН Способ получения концентрата фактора viii из плазмы крови человека
US9488625B2 (en) 2010-12-15 2016-11-08 Baxalta GmbH Purification of factor VIII using a conductivity gradient
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
FR3034669B1 (fr) 2015-04-07 2020-02-14 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Nouvelle utilisation du facteur von willebrand
WO2019050321A1 (ko) * 2017-09-07 2019-03-14 (주)프로테옴텍 다수의 검사선을 구비한 크로마토그래피용 스트립, 이를 포함하는 진단 키트 및 다수의 경쟁적 반응 측정 단계를 포함하는 정성, 반정량, 정량 분석방법
EP3488858A1 (en) 2017-11-27 2019-05-29 Laboratoire Français du Fractionnement et des Biotechnologies A von willebrand factor composition for use in treating a pathology mediated by angiogenesis

Citations (2)

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Publication number Priority date Publication date Assignee Title
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EP1042976A1 (en) 1999-04-08 2000-10-11 Challenger Gestao E Consultadoria Sociedade Unipessoal Limitada Chair or the like with facilitated assembly

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FR2570276B1 (fr) * 1984-09-18 1987-09-04 Immunotech Sa Procede d'obtention du complexe fviii/vwf a usage therapeutique et produits en resultant
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Also Published As

Publication number Publication date
DE68922358T2 (de) 1995-10-12
WO1989012065A1 (fr) 1989-12-14
ATE121750T1 (de) 1995-05-15
AU1138392A (en) 1992-05-14
RU1837880C (ru) 1993-08-30
NO900529D0 (no) 1990-02-05
US5252709A (en) 1993-10-12
DE68922358T3 (de) 2004-08-19
ES2070919T3 (es) 1995-06-16
FI96210B (fi) 1996-02-15
DE68922358D1 (de) 1995-06-01
DK175322B1 (da) 2004-08-23
AU622436B2 (en) 1992-04-09
NO177188B (no) 1995-04-24
DE359593T1 (de) 1990-09-27
KR970010923B1 (ko) 1997-07-02
FR2632309A1 (fr) 1989-12-08
CA1340742C (fr) 1999-09-14
NO177188C (no) 1995-08-02
EP0359593B1 (fr) 1995-04-26
DK29990A (da) 1990-03-28
EP0359593B2 (fr) 2004-01-07
ES2070919T5 (es) 2004-07-16
FI96210C (fi) 1996-05-27
UA11061A (uk) 1996-12-25
NO900529L (no) 1990-04-06
JPH03501974A (ja) 1991-05-09
FI900397A0 (fi) 1990-01-25
EP0359593A1 (fr) 1990-03-21
AU3068289A (en) 1990-01-05
JP2805364B2 (ja) 1998-09-30
KR900701823A (ko) 1990-12-04
DK29990D0 (da) 1990-02-06
FR2632309B1 (fr) 1990-08-24
LTIP262A (en) 1994-10-25

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Owner name: THE LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES

Effective date: 20090511

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Representative=s name: ZABOLIENE, REDA, LT

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Effective date: 20091229