IT1396528B1 - Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn). - Google Patents
Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn).Info
- Publication number
- IT1396528B1 IT1396528B1 ITFI2009A000007A ITFI20090007A IT1396528B1 IT 1396528 B1 IT1396528 B1 IT 1396528B1 IT FI2009A000007 A ITFI2009A000007 A IT FI2009A000007A IT FI20090007 A ITFI20090007 A IT FI20090007A IT 1396528 B1 IT1396528 B1 IT 1396528B1
- Authority
- IT
- Italy
- Prior art keywords
- vwf
- fibronectin
- purification process
- highly selective
- von willebrand
- Prior art date
Links
- 102100037362 Fibronectin Human genes 0.000 title 2
- 108010067306 Fibronectins Proteins 0.000 title 2
- 108010047303 von Willebrand Factor Proteins 0.000 title 2
- 102100036537 von Willebrand factor Human genes 0.000 title 2
- 229960001134 von willebrand factor Drugs 0.000 title 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITFI2009A000007A IT1396528B1 (it) | 2009-01-19 | 2009-01-19 | Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn). |
AU2010205403A AU2010205403B2 (en) | 2009-01-19 | 2010-01-19 | New process for highly selective purification of two plasma proteins: von Willebrand factor (vWF) and Fibronectin (Fn) |
ES10706368T ES2420535T3 (es) | 2009-01-19 | 2010-01-19 | Nuevo proceso para la purificación altamente selectiva de dos proteínas plasmáticas: factor de von willebrand (vwf) y fibronectina (fn). |
EP10706368.7A EP2387582B1 (en) | 2009-01-19 | 2010-01-19 | New process for highly selective purification of two plasma proteins: von willebrand factor (vwf) and fibronectin (fn) |
US13/145,038 US9422361B2 (en) | 2009-01-19 | 2010-01-19 | Process for highly selective purification of two plasma proteins: von willebrand factor (vWF) and fibronectin (Fn) |
PCT/IB2010/050230 WO2010082184A1 (en) | 2009-01-19 | 2010-01-19 | New process for highly selective purification of two plasma proteins: von willebrand factor (vwf) and fibronectin (fn) |
CA2749902A CA2749902C (en) | 2009-01-19 | 2010-01-19 | New process for highly selective purification of two plasma proteins: von willebrand factor (vwf) and fibronectin (fn) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITFI2009A000007A IT1396528B1 (it) | 2009-01-19 | 2009-01-19 | Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn). |
Publications (2)
Publication Number | Publication Date |
---|---|
ITFI20090007A1 ITFI20090007A1 (it) | 2010-07-20 |
IT1396528B1 true IT1396528B1 (it) | 2012-12-14 |
Family
ID=40941762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITFI2009A000007A IT1396528B1 (it) | 2009-01-19 | 2009-01-19 | Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn). |
Country Status (7)
Country | Link |
---|---|
US (1) | US9422361B2 (it) |
EP (1) | EP2387582B1 (it) |
AU (1) | AU2010205403B2 (it) |
CA (1) | CA2749902C (it) |
ES (1) | ES2420535T3 (it) |
IT (1) | IT1396528B1 (it) |
WO (1) | WO2010082184A1 (it) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103274954B (zh) * | 2013-05-22 | 2016-01-06 | 厦门世达膜科技有限公司 | 一种甘氨酸生产工艺 |
CN105622747A (zh) * | 2016-02-04 | 2016-06-01 | 江西博雅生物制药股份有限公司 | 一种vWF活性保护液 |
CN105541997A (zh) * | 2016-02-04 | 2016-05-04 | 江西博雅生物制药股份有限公司 | 一种高纯度和高活性血管性血友病因子的制备工艺 |
CN105622746A (zh) * | 2016-02-04 | 2016-06-01 | 江西博雅生物制药股份有限公司 | 一种从冷沉淀提取凝血因子ⅷ的废料中提取人血管性血友病因子的制备工艺 |
CN111491949B (zh) * | 2017-10-27 | 2024-01-09 | 株式会社绿十字控股 | 用于制备具有血管性血友病因子(vwf)受控含量的含有因子viii(fviii)和血管性血友病因子的组合物的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2632309B1 (fr) * | 1988-06-07 | 1990-08-24 | Lille Transfusion Sanguine | Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus |
FR2665449B1 (fr) | 1990-08-02 | 1995-04-14 | Aquitaine Developp Transf Sang | Procede de fabrication de facteur von willebrand ayant une tres haute purete, depourvu en majeure partie de facteur antihemophilique (fviiic), et facteur von willebrand ainsi obtenu, ainsi qu'une composition pharmaceutique le contenant. |
FR2673632A1 (fr) | 1991-03-08 | 1992-09-11 | Lille Transfusion Sanguine | Procede de preparation de concentre de facteur von willebrand humain de tres haute purete, approprie a un usage therapeutique. |
AT406867B (de) | 1997-02-27 | 2000-10-25 | Immuno Ag | Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex |
EP1148063A1 (de) * | 2000-04-18 | 2001-10-24 | Octapharma AG | Haemostatisch aktives vWF enthaltendes Präparat und Verfahren zu seiner Herstellung |
FR2874216B1 (fr) | 2004-08-16 | 2006-11-03 | Lab Francais Du Fractionnement | Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu |
DE102004044429B4 (de) * | 2004-09-14 | 2009-04-30 | Biotest Ag | Verfahren zur Herstellung einer Zusammensetzung enthaltend von Willebrand Faktor |
ITLU20070007A1 (it) | 2007-05-07 | 2008-11-08 | Kedrion Spa | Processo cromatografico per l'ottenimento di un complesso fviii/vwf con differenti rapporti tra le due proteine da utilizzare nella terapia della emofilia a e nella malattia di von willebrand. |
-
2009
- 2009-01-19 IT ITFI2009A000007A patent/IT1396528B1/it active
-
2010
- 2010-01-19 CA CA2749902A patent/CA2749902C/en active Active
- 2010-01-19 US US13/145,038 patent/US9422361B2/en active Active
- 2010-01-19 EP EP10706368.7A patent/EP2387582B1/en active Active
- 2010-01-19 WO PCT/IB2010/050230 patent/WO2010082184A1/en active Application Filing
- 2010-01-19 ES ES10706368T patent/ES2420535T3/es active Active
- 2010-01-19 AU AU2010205403A patent/AU2010205403B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2387582A1 (en) | 2011-11-23 |
AU2010205403B2 (en) | 2014-04-10 |
ES2420535T3 (es) | 2013-08-23 |
CA2749902A1 (en) | 2010-07-22 |
ITFI20090007A1 (it) | 2010-07-20 |
AU2010205403A1 (en) | 2011-09-01 |
WO2010082184A1 (en) | 2010-07-22 |
US20110282032A1 (en) | 2011-11-17 |
EP2387582B1 (en) | 2013-04-17 |
US9422361B2 (en) | 2016-08-23 |
CA2749902C (en) | 2019-09-17 |
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