KR960701052A - 피롤로-피리딘 유도체(Pyrrolo-pyridine derivatives) - Google Patents

피롤로-피리딘 유도체(Pyrrolo-pyridine derivatives)

Info

Publication number
KR960701052A
KR960701052A KR1019950703674A KR19950703674A KR960701052A KR 960701052 A KR960701052 A KR 960701052A KR 1019950703674 A KR1019950703674 A KR 1019950703674A KR 19950703674 A KR19950703674 A KR 19950703674A KR 960701052 A KR960701052 A KR 960701052A
Authority
KR
South Korea
Prior art keywords
pyrrolo
pyridine derivatives
pyridine
derivatives
Prior art date
Application number
KR1019950703674A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939304111A external-priority patent/GB9304111D0/en
Priority claimed from GB939316275A external-priority patent/GB9316275D0/en
Application filed filed Critical
Publication of KR960701052A publication Critical patent/KR960701052A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019950703674A 1993-03-01 1995-08-31 피롤로-피리딘 유도체(Pyrrolo-pyridine derivatives) KR960701052A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939304111A GB9304111D0 (en) 1993-03-01 1993-03-01 Therapeutic agents
GB939316275A GB9316275D0 (en) 1993-08-05 1993-08-05 Therapeutic agents
PCT/GB1994/000337 WO1994020497A1 (en) 1993-03-01 1994-02-21 Pyrrolo-pyridine derivatives

Publications (1)

Publication Number Publication Date
KR960701052A true KR960701052A (ko) 1996-02-24

Family

ID=26302519

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950703674A KR960701052A (ko) 1993-03-01 1995-08-31 피롤로-피리딘 유도체(Pyrrolo-pyridine derivatives)

Country Status (20)

Country Link
US (1) US5432177A (ko)
EP (1) EP0623618A3 (ko)
JP (1) JP2710751B2 (ko)
KR (1) KR960701052A (ko)
CN (1) CN1118598A (ko)
AU (1) AU674373B2 (ko)
BG (1) BG99885A (ko)
BR (1) BR9406128A (ko)
CA (1) CA2116213A1 (ko)
CZ (1) CZ224195A3 (ko)
FI (1) FI954088A0 (ko)
HU (1) HUT71799A (ko)
IL (1) IL108729A0 (ko)
NO (1) NO953406L (ko)
NZ (1) NZ261593A (ko)
PL (1) PL310443A1 (ko)
SI (1) SI9400091A (ko)
SK (1) SK106395A3 (ko)
WO (1) WO1994020497A1 (ko)
YU (1) YU9194A (ko)

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US5814644A (en) * 1993-04-15 1998-09-29 Merck Sharp & Dohme, Ltd. Indole derivatives as dopamine D4 antagonists
MXPA94006948A (es) 1993-09-10 2003-12-02 Cytomed Inc Epibatidina y derivados de la misma como agonistasy antagonistas del receptor colinergico.
US6117889A (en) * 1994-04-01 2000-09-12 University Of Virginia 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents
JPH10501212A (ja) * 1994-05-19 1998-02-03 メルク シヤープ エンド ドーム リミテツド ５−ｈｔ▲下１ｄ▼−アルファ作働薬としてのインドール−３−イルアルキルのピペラジン、ピペリジンおよびテトラヒドロピリジン誘導体
AU681310B2 (en) * 1994-09-30 1997-08-21 Pfizer Inc. 2,7-substituted octahydro-1h-pyrido{1,2-a}pyrazine derivatives
GB9423460D0 (en) * 1994-11-21 1995-01-11 Merck Sharp & Dohme Therapeutic agents
EP0809642A1 (en) * 1995-02-15 1997-12-03 PHARMACIA & UPJOHN COMPANY Imidazo 1,2-a]pyridines for the treatment of cns and cardiac diseases
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GB9507291D0 (en) * 1995-04-07 1995-05-31 Merck Sharp & Dohme Therapeutic agents
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
US5725838A (en) * 1996-05-31 1998-03-10 Resolution Pharmaceuticals, Inc. Radiolabeled D4 receptor ligands
DE19637237A1 (de) 1996-09-13 1998-03-19 Merck Patent Gmbh Piperazin-Derivate
AU8096798A (en) * 1997-06-27 1999-01-19 Resolution Pharmaceuticals Inc. Dopamine d4 receptor ligands
US5976497A (en) * 1997-08-04 1999-11-02 Resolution Pharmaceuticals, Inc. Dopamine D4 receptor ligands
US6013654A (en) * 1997-08-14 2000-01-11 Pharmacia & Upjohn Company Imidazo[1,2-A]pyridines for the treatment of CNS and cardiac diseases
WO2001012629A1 (en) * 1999-08-12 2001-02-22 Nps Allelix Corp. Azaindoles having serotonin receptor affinity
US6686374B1 (en) 1999-08-12 2004-02-03 Nps Allelix Corp. Azaindoles having serotonin receptor affinity
AR028945A1 (es) * 2000-06-19 2003-05-28 Lundbeck & Co As H Derivados de indol
KR20030011365A (ko) * 2000-06-29 2003-02-07 하. 룬트벡 아크티에 셀스카브 Ｃｎｓ 장애 치료에 유용한 인돌 유도체
DK1325008T3 (da) * 2000-07-31 2006-02-13 Hoffmann La Roche Piperazinderivater
US7432304B2 (en) 2001-05-30 2008-10-07 The Regents Of The University Of Michigan Small molecule antagonists of Bcl-2 family proteins
CA2450315A1 (en) * 2001-06-13 2002-12-19 The Regents Of The University Of Michigan Dopamine receptor ligands and therapeutic methods based thereon
AU2002360335A1 (en) 2001-11-01 2003-05-12 The Regents Of The University Of Michigan Small molecule inhibitors targeted at bcl-2
CN100347171C (zh) * 2002-02-08 2007-11-07 中国科学院上海原子核研究所 一种吡啶类化合物及其制备方法和作为多巴胺d4受体拮抗剂的应用
CN1305873C (zh) * 2002-07-12 2007-03-21 中国科学院上海原子核研究所 [18f]氟标记的吡啶类化合物及其制备方法和作为多巴胺d4受体显像剂的应用
JP2004123562A (ja) * 2002-09-30 2004-04-22 Japan Science & Technology Corp 神経細胞死抑制作用を有する化合物を用いた医薬
GB0314967D0 (en) * 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
DK1696920T3 (en) * 2003-12-19 2015-01-19 Plexxikon Inc RELATIONS AND PROCEDURES FOR THE DEVELOPMENT OF LAW MODULATORS
US20070066641A1 (en) * 2003-12-19 2007-03-22 Prabha Ibrahim Compounds and methods for development of RET modulators
SG151299A1 (en) 2004-03-25 2009-04-30 Univ Michigan Gossypol co-crystals and the use thereof
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
JP2008503473A (ja) * 2004-06-17 2008-02-07 プレキシコン，インコーポレーテッド Ｃ−ｋｉｔ活性を調節する化合物
DE102004054634A1 (de) * 2004-11-12 2006-05-18 Schwarz Pharma Ag Azaindolcarboxamide
WO2007013896A2 (en) * 2005-05-17 2007-02-01 Plexxikon, Inc. Pyrrol (2,3-b) pyridine derivatives protein kinase inhibitors
DK1893612T3 (da) * 2005-06-22 2011-11-21 Plexxikon Inc Pyrrol [2,3-B]pyridin-derivater som proteinkinasehæmmere
US7544685B2 (en) 2005-08-17 2009-06-09 H. Lundbeck A/S 2,3-dihydroindole compounds
JP2010519171A (ja) 2006-02-17 2010-06-03 メモリー・ファーマシューティカルズ・コーポレイション ５−ｈｔ６受容体親和性を有する化合物
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WO2008079909A1 (en) * 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
AU2007336811A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
WO2009012283A1 (en) 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
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US8518933B2 (en) 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
US8546377B2 (en) * 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
JP2013510166A (ja) 2009-11-06 2013-03-21 プレキシコン インコーポレーテッド キナーゼ調節のための化合物、方法およびその適用
EP2646437B1 (en) * 2010-12-02 2014-09-03 Eli Lilly and Company 3-substituted-6-(pyridinylmethoxy)-pyrrolopyridine compounds
AU2012214762B2 (en) 2011-02-07 2015-08-13 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
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US20150291625A1 (en) * 2012-11-08 2015-10-15 Pfizer Inc. Heteroaromatic Compounds and their Use as Dopamine D1 Ligands

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US3511841A (en) * 1967-05-29 1970-05-12 Sterling Drug Inc 1-((4-,5-,6-,and 7-azaindolyl)-lower-alkyl)- 4-substituted-piperazines
US5422265A (en) * 1990-12-07 1995-06-06 State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The Oregon Health Sciences University DNA sequence for the human dopamine receptor D4 and expression thereof in mammalian cells

Also Published As

Publication number Publication date
IL108729A0 (en) 1994-05-30
WO1994020497A1 (en) 1994-09-15
SK106395A3 (en) 1995-12-06
EP0623618A3 (en) 1997-04-02
JPH06279442A (ja) 1994-10-04
AU674373B2 (en) 1996-12-19
HUT71799A (en) 1996-02-28
JP2710751B2 (ja) 1998-02-10
NO953406D0 (no) 1995-08-30
CZ224195A3 (en) 1996-03-13
SI9400091A (en) 1994-12-31
FI954088A (fi) 1995-08-31
YU9194A (sh) 1997-08-22
EP0623618A2 (en) 1994-11-09
CN1118598A (zh) 1996-03-13
US5432177A (en) 1995-07-11
PL310443A1 (en) 1995-12-11
FI954088A0 (fi) 1995-08-31
HU9501871D0 (en) 1995-08-28
BR9406128A (pt) 1996-02-27
CA2116213A1 (en) 1994-09-02
NZ261593A (en) 1996-09-25
AU5647094A (en) 1994-09-08
NO953406L (no) 1995-10-31
BG99885A (en) 1996-02-29

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Legal Events

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