DE69330497T2 - Chinazolin-derivate - Google Patents

Chinazolin-derivate

Info

Publication number
DE69330497T2
DE69330497T2 DE69330497T DE69330497T DE69330497T2 DE 69330497 T2 DE69330497 T2 DE 69330497T2 DE 69330497 T DE69330497 T DE 69330497T DE 69330497 T DE69330497 T DE 69330497T DE 69330497 T2 DE69330497 T2 DE 69330497T2
Authority
DE
Germany
Prior art keywords
quinazoline derivatives
quinazoline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330497T
Other languages
English (en)
Other versions
DE69330497D1 (de
Inventor
Jong Wook Lee
Jeong Seok Chae
Chang Seop Kim
Jae Kyu Kim
Dae Sung Lim
Jeong Won Lee
Moon Kyu Shon
Dae Woong Jo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yuhan Corp
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of DE69330497D1 publication Critical patent/DE69330497D1/de
Application granted granted Critical
Publication of DE69330497T2 publication Critical patent/DE69330497T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69330497T 1992-12-29 1993-10-29 Chinazolin-derivate Expired - Fee Related DE69330497T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR920026290 1992-12-29
PCT/KR1993/000096 WO1994014795A1 (en) 1992-12-29 1993-10-29 Quinazoline derivatives

Publications (2)

Publication Number Publication Date
DE69330497D1 DE69330497D1 (de) 2001-08-30
DE69330497T2 true DE69330497T2 (de) 2002-05-29

Family

ID=19347436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330497T Expired - Fee Related DE69330497T2 (de) 1992-12-29 1993-10-29 Chinazolin-derivate

Country Status (7)

Country Link
US (1) US5686458A (de)
EP (1) EP0677049B1 (de)
JP (1) JP2654585B2 (de)
KR (1) KR0144833B1 (de)
DE (1) DE69330497T2 (de)
ES (1) ES2160106T3 (de)
WO (1) WO1994014795A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69530989T2 (de) * 1994-08-13 2004-05-19 Yuhan Corp. Neue pyrimidinderivate und verfahren zu ihrer herstellung
WO1997020822A1 (en) * 1995-12-01 1997-06-12 Novartis Ag Quinazolin-2,4-diazirines as npy receptor antagonist
EP0900214B1 (de) * 1996-05-04 2001-09-26 Yuhan Corporation Verfahren zur herstellung von pyrimidin-derivaten
US6252076B1 (en) 1996-05-04 2001-06-26 Yuhan Corporation Process for preparation of pyrimidine derivatives
TR199900943T2 (xx) * 1996-10-29 1999-12-21 Yuhan Corporation Pirimidin t�revlerinin haz�rlanma prosesi.
IN188411B (de) * 1997-03-27 2002-09-21 Yuhan Corp
US6706721B1 (en) 1998-04-29 2004-03-16 Osi Pharmaceuticals, Inc. N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
UA74803C2 (uk) 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
US7087613B2 (en) * 1999-11-11 2006-08-08 Osi Pharmaceuticals, Inc. Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
US6900226B2 (en) * 2000-09-06 2005-05-31 Hoffman-La Roche Inc. Neuropeptide Y antagonists
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
JP4634144B2 (ja) * 2002-08-01 2011-02-16 ニコックス エスエー ニトロソ化プロトンポンプ阻害剤、組成物および使用方法
BRPI0406427B8 (pt) 2003-03-10 2021-05-25 Astrazeneca Ab processo para a preparação de roflumilast
EP1682133A1 (de) 2003-11-03 2006-07-26 AstraZeneca AB Imidazo-1,2-a-pyridin-derivate zur behandlung von beschwerdefreiem gastroösophagealem reflux
US20070237315A1 (en) * 2004-02-24 2007-10-11 First Data Corporation System for maintaining type and/or status information for a party - communication point relationship
BRPI0514695A (pt) 2004-09-03 2008-06-17 Yuhan Corp derivados de pirrol[3, 2-b]piridina e processos para a preparação destes
DK1861074T3 (da) 2005-03-16 2013-07-29 Takeda Gmbh Smagsmaskeret doseringsform indeholdende roflumilast
KR101657616B1 (ko) * 2013-05-24 2016-09-19 주식회사유한양행 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법
CN104903312B (zh) * 2013-10-07 2019-01-29 卡德门企业有限公司 Rho激酶抑制剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044136A (en) * 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US3956495A (en) * 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
IL88507A (en) 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
CA2015981A1 (en) 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
CA2095213A1 (en) * 1990-11-06 1992-05-07 Jotham W. Coe Quinazoline derivatives for enhancing antitumor activity

Also Published As

Publication number Publication date
EP0677049A1 (de) 1995-10-18
ES2160106T3 (es) 2001-11-01
KR940014385A (ko) 1994-07-18
JPH08500841A (ja) 1996-01-30
WO1994014795A1 (en) 1994-07-07
KR0144833B1 (ko) 1998-07-15
DE69330497D1 (de) 2001-08-30
JP2654585B2 (ja) 1997-09-17
EP0677049B1 (de) 2001-07-25
US5686458A (en) 1997-11-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee