DE69330497D1 - Chinazolin-derivate - Google Patents

Chinazolin-derivate

Info

Publication number
DE69330497D1
DE69330497D1 DE69330497T DE69330497T DE69330497D1 DE 69330497 D1 DE69330497 D1 DE 69330497D1 DE 69330497 T DE69330497 T DE 69330497T DE 69330497 T DE69330497 T DE 69330497T DE 69330497 D1 DE69330497 D1 DE 69330497D1
Authority
DE
Germany
Prior art keywords
chinazolin
derivatives
chinazolin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330497T
Other languages
English (en)
Other versions
DE69330497T2 (de
Inventor
Jong Wook Lee
Jeong Seok Chae
Chang Seop Kim
Jae Kyu Kim
Dae Sung Lim
Jeong Won Lee
Moon Kyu Shon
Dae Woong Jo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yuhan Corp
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of DE69330497D1 publication Critical patent/DE69330497D1/de
Application granted granted Critical
Publication of DE69330497T2 publication Critical patent/DE69330497T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DE69330497T 1992-12-29 1993-10-29 Chinazolin-derivate Expired - Fee Related DE69330497T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR920026290 1992-12-29
PCT/KR1993/000096 WO1994014795A1 (en) 1992-12-29 1993-10-29 Quinazoline derivatives

Publications (2)

Publication Number Publication Date
DE69330497D1 true DE69330497D1 (de) 2001-08-30
DE69330497T2 DE69330497T2 (de) 2002-05-29

Family

ID=19347436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330497T Expired - Fee Related DE69330497T2 (de) 1992-12-29 1993-10-29 Chinazolin-derivate

Country Status (7)

Country Link
US (1) US5686458A (de)
EP (1) EP0677049B1 (de)
JP (1) JP2654585B2 (de)
KR (1) KR0144833B1 (de)
DE (1) DE69330497T2 (de)
ES (1) ES2160106T3 (de)
WO (1) WO1994014795A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69530989T2 (de) * 1994-08-13 2004-05-19 Yuhan Corp. Neue pyrimidinderivate und verfahren zu ihrer herstellung
AU7692896A (en) * 1995-12-01 1997-06-27 Novartis Ag Quinazolin-2,4-diazirines as NPY receptor antagonist
US6252076B1 (en) 1996-05-04 2001-06-26 Yuhan Corporation Process for preparation of pyrimidine derivatives
PT900214E (pt) * 1996-05-04 2002-03-28 Yuhan Corp Processo para a preparacao de derivados da pirimidina
HU226752B1 (en) * 1996-10-29 2009-09-28 Yuhan Corp Process for preparation of pyrimidine derivatives
IN188411B (de) * 1997-03-27 2002-09-21 Yuhan Corp
US6706721B1 (en) 1998-04-29 2004-03-16 Osi Pharmaceuticals, Inc. N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
US7087613B2 (en) * 1999-11-11 2006-08-08 Osi Pharmaceuticals, Inc. Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
UA74803C2 (uk) 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
US6900226B2 (en) * 2000-09-06 2005-05-31 Hoffman-La Roche Inc. Neuropeptide Y antagonists
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2493618A1 (en) * 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
DE602004023921D1 (de) 2003-03-10 2009-12-17 Nycomed Gmbh Neues verfahren zur herstellung vonroflumilast
CN1874772A (zh) 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2－a]吡啶衍生物
US20070237315A1 (en) * 2004-02-24 2007-10-11 First Data Corporation System for maintaining type and/or status information for a party - communication point relationship
JP4989478B2 (ja) 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｂ］ピリジン誘導体及びその製造方法
US8663694B2 (en) 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
KR101657616B1 (ko) * 2013-05-24 2016-09-19 주식회사유한양행 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법
CN104903312B (zh) * 2013-10-07 2019-01-29 卡德门企业有限公司 Rho激酶抑制剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) * 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) * 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
HUT64533A (en) * 1990-11-06 1994-01-28 Pfizer Method for producing quinazoline derivatives for improving anti-tumoric activity and preparations containing said compounds

Also Published As

Publication number Publication date
JP2654585B2 (ja) 1997-09-17
JPH08500841A (ja) 1996-01-30
KR940014385A (ko) 1994-07-18
ES2160106T3 (es) 2001-11-01
WO1994014795A1 (en) 1994-07-07
US5686458A (en) 1997-11-11
EP0677049B1 (de) 2001-07-25
DE69330497T2 (de) 2002-05-29
EP0677049A1 (de) 1995-10-18
KR0144833B1 (ko) 1998-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee