BG99885A - Pyrene-pyridine derivatives - Google Patents

Pyrene-pyridine derivatives

Info

Publication number
BG99885A
BG99885A BG99885A BG9988595A BG99885A BG 99885 A BG99885 A BG 99885A BG 99885 A BG99885 A BG 99885A BG 9988595 A BG9988595 A BG 9988595A BG 99885 A BG99885 A BG 99885A
Authority
BG
Bulgaria
Prior art keywords
pyridine derivatives
dopamine
pyrene
substituted
receptor
Prior art date
Application number
BG99885A
Other languages
Bulgarian (bg)
English (en)
Inventor
Raymond Baker
Neil CURTIS
Janusz Kulagowski
Paul Leeson
Mark Ridgill
Adrian Smith
Original Assignee
Raymond Baker
Neil CURTIS
Janusz Kulagowski
Paul Leeson
Mark Ridgill
Adrian Smith
Merck Sharp & Dohme Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939304111A external-priority patent/GB9304111D0/en
Priority claimed from GB939316275A external-priority patent/GB9316275D0/en
Application filed by Raymond Baker, Neil CURTIS, Janusz Kulagowski, Paul Leeson, Mark Ridgill, Adrian Smith, Merck Sharp & Dohme Limited filed Critical Raymond Baker
Publication of BG99885A publication Critical patent/BG99885A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BG99885A 1993-03-01 1995-08-24 Pyrene-pyridine derivatives BG99885A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939304111A GB9304111D0 (en) 1993-03-01 1993-03-01 Therapeutic agents
GB939316275A GB9316275D0 (en) 1993-08-05 1993-08-05 Therapeutic agents
PCT/GB1994/000337 WO1994020497A1 (en) 1993-03-01 1994-02-21 Pyrrolo-pyridine derivatives

Publications (1)

Publication Number Publication Date
BG99885A true BG99885A (en) 1996-02-29

Family

ID=26302519

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99885A BG99885A (en) 1993-03-01 1995-08-24 Pyrene-pyridine derivatives

Country Status (20)

Country Link
US (1) US5432177A (xx)
EP (1) EP0623618A3 (xx)
JP (1) JP2710751B2 (xx)
KR (1) KR960701052A (xx)
CN (1) CN1118598A (xx)
AU (1) AU674373B2 (xx)
BG (1) BG99885A (xx)
BR (1) BR9406128A (xx)
CA (1) CA2116213A1 (xx)
CZ (1) CZ224195A3 (xx)
FI (1) FI954088A (xx)
HU (1) HUT71799A (xx)
IL (1) IL108729A0 (xx)
NO (1) NO953406L (xx)
NZ (1) NZ261593A (xx)
PL (1) PL310443A1 (xx)
SI (1) SI9400091A (xx)
SK (1) SK106395A3 (xx)
WO (1) WO1994020497A1 (xx)
YU (1) YU9194A (xx)

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US6060473A (en) * 1993-04-01 2000-05-09 Ucb S.A. - Dtb 7-azabicyclo[2.2.1]-heptane and -heptene derivatives as cholinergic receptor ligands
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US6117889A (en) * 1994-04-01 2000-09-12 University Of Virginia 7-Azabicyclo-[2.2.1]-heptane and -heptene derivatives as analgesics and anti-inflammatory agents
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SI9520096A (sl) * 1994-09-30 1998-04-30 Pfizer Inc. Derivati 2,7-substituiranega oktahidro-1H-pirido /1,2-a/ pirazina
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US5725838A (en) * 1996-05-31 1998-03-10 Resolution Pharmaceuticals, Inc. Radiolabeled D4 receptor ligands
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CZ20024192A3 (cs) * 2000-06-29 2003-04-16 H. Lundbeck A/S Indolové deriváty
CN1277828C (zh) 2000-07-31 2006-10-04 霍夫曼-拉罗奇有限公司 哌嗪衍生物
US7432304B2 (en) 2001-05-30 2008-10-07 The Regents Of The University Of Michigan Small molecule antagonists of Bcl-2 family proteins
EP1406631A4 (en) * 2001-06-13 2005-03-23 Univ Michigan DOPAMINE RECEPTOR LIGANDS AND CORRESPONDING THERAPEUTIC METHODS
US7354928B2 (en) 2001-11-01 2008-04-08 The Regents Of The University Of Michigan Small molecule inhibitors targeted at Bcl-2
CN100347171C (zh) * 2002-02-08 2007-11-07 中国科学院上海原子核研究所 一种吡啶类化合物及其制备方法和作为多巴胺d4受体拮抗剂的应用
CN1305873C (zh) * 2002-07-12 2007-03-21 中国科学院上海原子核研究所 [18f]氟标记的吡啶类化合物及其制备方法和作为多巴胺d4受体显像剂的应用
JP2004123562A (ja) * 2002-09-30 2004-04-22 Japan Science & Technology Corp 神経細胞死抑制作用を有する化合物を用いた医薬
GB0314967D0 (en) * 2003-06-26 2003-07-30 Hoffmann La Roche Piperazine derivatives
US20070066641A1 (en) * 2003-12-19 2007-03-22 Prabha Ibrahim Compounds and methods for development of RET modulators
CA2550361C (en) * 2003-12-19 2014-04-29 Prabha Ibrahim Compounds and methods for development of ret modulators
AU2005228998B2 (en) 2004-03-25 2008-11-06 The Regents Of The University Of Michigan Gossypol co-crystals and the use thereof
CA2570817A1 (en) * 2004-06-17 2006-01-26 Plexxikon, Inc. Azaindoles modulating c-kit activity and uses therefor
US7498342B2 (en) * 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
DE102004054634A1 (de) * 2004-11-12 2006-05-18 Schwarz Pharma Ag Azaindolcarboxamide
KR20080027775A (ko) * 2005-05-17 2008-03-28 플렉시콘, 인코퍼레이티드 피롤(２,３-ｂ)피리딘 유도체 단백질 키나제 억제제
WO2007002325A1 (en) * 2005-06-22 2007-01-04 Plexxikon, Inc. Pyrrolo[2,3-b] pyridine derivatives as protein kinase inhibitors
US7544685B2 (en) 2005-08-17 2009-06-09 H. Lundbeck A/S 2,3-dihydroindole compounds
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PE20121126A1 (es) * 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008080015A2 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
WO2008079909A1 (en) * 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
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US8518933B2 (en) * 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
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CA2819840C (en) * 2010-12-02 2015-05-26 Eli Lily And Company 3-substituted-6-(pyridinylmethoxy)-pyrrolopyridine compounds
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Also Published As

Publication number Publication date
SK106395A3 (en) 1995-12-06
HUT71799A (en) 1996-02-28
AU5647094A (en) 1994-09-08
IL108729A0 (en) 1994-05-30
PL310443A1 (en) 1995-12-11
FI954088A0 (fi) 1995-08-31
US5432177A (en) 1995-07-11
NO953406D0 (no) 1995-08-30
CA2116213A1 (en) 1994-09-02
YU9194A (sh) 1997-08-22
EP0623618A3 (en) 1997-04-02
AU674373B2 (en) 1996-12-19
HU9501871D0 (en) 1995-08-28
FI954088A (fi) 1995-08-31
NZ261593A (en) 1996-09-25
KR960701052A (ko) 1996-02-24
CN1118598A (zh) 1996-03-13
SI9400091A (en) 1994-12-31
CZ224195A3 (en) 1996-03-13
WO1994020497A1 (en) 1994-09-15
JPH06279442A (ja) 1994-10-04
JP2710751B2 (ja) 1998-02-10
NO953406L (no) 1995-10-31
EP0623618A2 (en) 1994-11-09
BR9406128A (pt) 1996-02-27

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