KR960028919A - 당 피막으로부터 스테로이드의 조절된 방출 - Google Patents
당 피막으로부터 스테로이드의 조절된 방출 Download PDFInfo
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- KR960028919A KR960028919A KR1019960000693A KR19960000693A KR960028919A KR 960028919 A KR960028919 A KR 960028919A KR 1019960000693 A KR1019960000693 A KR 1019960000693A KR 19960000693 A KR19960000693 A KR 19960000693A KR 960028919 A KR960028919 A KR 960028919A
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- Prior art keywords
- sucrose
- saccharide
- lactose
- steroid hormone
- microcrystalline cellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
본 발명은 당, 투여량의 스테로이드 호르몬 및 스테로이드 방출 속도 조절량의 미소결정질 셀룰로오즈를 함유하는 의약용 압축 정제에 적용하기 위한 당 피복 조성물에 관한 것이다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (7)
- 당, 투여 용량의 스테로이드 호르몬 및 스테로이드 방출 속도 조절량의 미소결정질 셀룰로오즈를 함유하는 압축된 의약용 정제에 적용하기 위한 당 피복 조성물.
- 제1항에 있어서, 당이 슈크로오즈인 당 피복 조성물.
- 제1항에 있어서, 스테로이드 호르몬이 메드록시프로게스터론 아세테이트, 레보노르게스트렐, 게스토덴, 메드로게스톤,에스트라디올, 에스트리올, 에틴닐에스트라디올, 메스트라놀, 에스트론, 디엔에스트롤, 헥세스트롤, 디에틸스틸베스트롤, 프로게스테론, 데소게스트렐, 노르게스티메이트, 하이드록시프로게스테론, 노르에틴드론, 노르에틴돈 아세테이트, 노르게스트렐, 메게스트롤 아세테이트, 메틸스토스테론, 에틸에스트레놀, 메탄디에논, 옥산드롤론 또는 트리메게스톤인 당 피복 조성물.
- 제1항에 있서, 슈크로오즈, 약 0.1중량% 내지 약 3중량%의 미소결정질 셀룰로오즈, 0 내지 약 5중량%의 폴리비닐피롤리돈, 약 0.1 내지 약 20중량%의 스테로이드 호르몬 및 수용액을 함유하는 당 피복 조성물.
- 배합된 에스트로겐을 함유하는 정제 코어, 및 스테로이드 호르몬과 방출 속도 조절량의 미소결정질 셀룰로오즈를 함유한 당 피막을 포함하는 압축 정제.
- 제5항에 있어서, 정제 코어가 배합된 에스트로겐 약 0.1 내지 약 5.0㎎을 함유하고 당 피막이 스테로이드 호르몬 약 1.0 내지 약 50㎎을 함유하는 압축 정제.
- 제5항에 있어서, 정제 코어가 배합된 에스트로겐 약 0.3 내지 약 2.5㎎을 함유하고 당 피막이 메드록시프로게스테론 아세테이트 약 1.5 내지 약 30㎎을 함유하는 압축 정제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/373,667 US5547948A (en) | 1995-01-17 | 1995-01-17 | Controlled release of steroids from sugar coatings |
US08/373,667 | 1995-01-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR960028919A true KR960028919A (ko) | 1996-08-17 |
KR100338581B1 KR100338581B1 (ko) | 2002-11-23 |
Family
ID=23473354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019960000693A KR100338581B1 (ko) | 1995-01-17 | 1996-01-16 | 스테로이드의제어방출용당의조성물및이를함유하는압축정제 |
Country Status (35)
Country | Link |
---|---|
US (2) | US5547948A (ko) |
EP (1) | EP0722720B1 (ko) |
JP (1) | JP3833292B2 (ko) |
KR (1) | KR100338581B1 (ko) |
CN (1) | CN1106839C (ko) |
AR (1) | AR002019A1 (ko) |
AT (1) | ATE185482T1 (ko) |
AU (1) | AU705879B2 (ko) |
BR (1) | BR9600100B1 (ko) |
CA (1) | CA2167254A1 (ko) |
CO (1) | CO4370096A1 (ko) |
CZ (1) | CZ286102B6 (ko) |
DE (1) | DE69604600T2 (ko) |
DK (1) | DK0722720T3 (ko) |
EE (1) | EE03802B1 (ko) |
EG (1) | EG23687A (ko) |
ES (1) | ES2137627T3 (ko) |
FI (1) | FI117592B (ko) |
GR (1) | GR3031920T3 (ko) |
HK (1) | HK1009935A1 (ko) |
HU (1) | HU223781B1 (ko) |
ID (1) | ID23996A (ko) |
IL (1) | IL116772A (ko) |
IS (1) | IS1878B (ko) |
MY (1) | MY115786A (ko) |
NO (1) | NO315307B1 (ko) |
NZ (1) | NZ280826A (ko) |
PL (1) | PL183330B1 (ko) |
RU (1) | RU2152207C1 (ko) |
SI (1) | SI0722720T1 (ko) |
SK (1) | SK280484B6 (ko) |
TR (1) | TR199600038A2 (ko) |
TW (1) | TW460301B (ko) |
UA (1) | UA37236C2 (ko) |
ZA (1) | ZA96301B (ko) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
US5759577A (en) * | 1995-01-17 | 1998-06-02 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
FR2736550B1 (fr) | 1995-07-14 | 1998-07-24 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule |
WO1997004752A1 (en) * | 1995-07-26 | 1997-02-13 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions of conjugated estrogens and methods for their use |
US6479475B1 (en) * | 1996-07-26 | 2002-11-12 | Wyeth | Oral contraceptive |
US6451778B1 (en) * | 1996-07-26 | 2002-09-17 | Wyeth | Oral contraceptive |
CA2230748C (en) * | 1997-03-14 | 2010-08-03 | American Home Products Corporation | Rapamycin formulations for oral administration |
DE19715594A1 (de) | 1997-04-15 | 1998-10-22 | Bayer Ag | Analgetika-Kombination |
US5985325A (en) * | 1997-06-13 | 1999-11-16 | American Home Products Corporation | Rapamycin formulations for oral administration |
ATE283687T1 (de) * | 1997-06-13 | 2004-12-15 | Wyeth Corp | Rapamycin-formulierungen zur oralen verabreichung |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
US6432448B1 (en) * | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
US6500462B1 (en) | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
FR2801218B1 (fr) * | 1999-11-23 | 2001-12-28 | Hoechst Marion Roussel Inc | Compositions pharmaceutiques comprenant de la trimegestone, leurs procedes de preparation ainsi que le conditionnement primaire les renfermant |
AT500063A1 (de) | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
US6660726B2 (en) | 2000-03-10 | 2003-12-09 | Endeavor Pharmaceuticals | Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same |
US7989436B2 (en) | 2003-07-23 | 2011-08-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and pharmaceutical formulations comprising the same |
US7459445B2 (en) * | 2000-03-10 | 2008-12-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and topical pharmaceutical formulations of the same |
US6855703B1 (en) | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
US20010034340A1 (en) * | 2000-03-20 | 2001-10-25 | American Home Products Corporation | Hormone replacement therapy |
TR200300731T2 (tr) | 2000-11-28 | 2004-08-23 | Fmc Corporation | Yenebilir PGA kaplama bileşimi |
US6630166B1 (en) * | 2001-02-12 | 2003-10-07 | Watson Pharmaceuticals, Inc. | Compositions for conjugated estrogens and associated methods |
US7303763B2 (en) * | 2001-02-12 | 2007-12-04 | Watson Laboratories, Inc. | Compositions for conjugated estrogens and associated methods |
JP2004533419A (ja) * | 2001-03-16 | 2004-11-04 | ワイス | ホルモン補充療法 |
BR0208165A (pt) * | 2001-03-16 | 2004-03-30 | Wyeth Corp | Composições farmacêuticas e seus usos na terapia de reposição de estrogênio |
UA77200C2 (en) | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
TW200306196A (en) * | 2002-04-03 | 2003-11-16 | Wyeth Corp | Hormone replacement therapy |
TW200306846A (en) * | 2002-04-03 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200306851A (en) * | 2002-04-29 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
TW200400040A (en) * | 2002-05-17 | 2004-01-01 | Wyeth Corp | Hormone replacement therapy |
US6992075B2 (en) * | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
EP1622623A4 (en) * | 2003-04-11 | 2009-03-18 | Barr Lab Inc | METHOD FOR THE ADMINISTRATION OF ESTROGENIC AND TESTED |
JP4880465B2 (ja) * | 2003-09-29 | 2012-02-22 | ノボ・ノルディスク・フェムケア・アーゲー | 向上した安定性のプロゲストーゲン製剤 |
PE20060245A1 (es) * | 2004-06-07 | 2006-05-03 | Wyeth Corp | Recubrimientos de azucar y metodos para la fabricacion de los mismos |
MX2007003519A (es) * | 2004-09-23 | 2007-08-07 | Fmc Corp | Composicion de recubrimiento. |
WO2006084082A1 (en) * | 2005-02-03 | 2006-08-10 | Duramed Pharmaceuticals, Inc. | Compositions of unconjugated estrogens and methods for their use |
WO2007002823A2 (en) * | 2005-06-29 | 2007-01-04 | Wyeth | Formulations of conjugated estrogens and bazedoxifene |
BRPI0718558A2 (pt) * | 2006-11-07 | 2013-11-19 | Wyeth Corp | Forma de dosagem sólida, composição aquosa, método para preparar uma forma de dosagem sólida, e, produto |
JP2010511062A (ja) * | 2006-11-29 | 2010-04-08 | ワイス エルエルシー | エストロゲン/sermおよびエストロゲン/プロゲスチン二層錠剤 |
WO2012120365A1 (en) | 2011-03-07 | 2012-09-13 | Aurobindo Pharma Limited | Stable pharmaceutical composition comprising ethinyl estradiol |
BR112013029199B1 (pt) * | 2011-05-13 | 2022-02-08 | Eb Ip Hybritabs B.V. | Dispositivo de distribuição de dois fármacos |
BR112014012444B1 (pt) | 2011-11-23 | 2021-12-14 | Therapeuticsmd, Inc | Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
EP2970839B1 (en) * | 2013-03-15 | 2017-02-22 | Monosol, LLC | Water-soluble film for delayed release |
US10808210B2 (en) | 2013-03-15 | 2020-10-20 | Monosol, Llc | Water-soluble film for delayed release |
RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
MX2018011705A (es) | 2016-04-01 | 2019-06-10 | Therapeuticsmd Inc | Composicion farmaceutica de hormona esteroide. |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
CN116236453A (zh) * | 2023-02-08 | 2023-06-09 | 江苏和汇医药科技有限公司 | 一种延长药品释放的糖包衣及其制备方法 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB844772A (en) * | 1956-04-19 | 1960-08-17 | Pfizer & Co C | Granular pharmaceutical compositions and process for preparing same |
GB888631A (en) * | 1959-02-24 | 1962-01-31 | Upjohn Co | Improvements in or relating to oral therapeutic compositions comprising steroids |
FR1396710A (fr) * | 1964-06-15 | 1965-04-23 | Diwag Chemische Fabriken G M B | Procédé pour la fabrication de charges ou supports perfectionnés et produits obtenus |
US3980766A (en) * | 1973-08-13 | 1976-09-14 | West Laboratories, Inc. | Orally administered drug composition for therapy in the treatment of narcotic drug addiction |
US4154820A (en) * | 1976-02-23 | 1979-05-15 | Akzona Incorporated | Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers |
US4248856A (en) * | 1979-07-10 | 1981-02-03 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4309404A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4309405A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
US4327076A (en) * | 1980-11-17 | 1982-04-27 | Life Savers, Inc. | Compressed chewable antacid tablet and method for forming same |
US4425339A (en) * | 1981-04-09 | 1984-01-10 | Syntex (U.S.A.) Inc. | Treatment of menopausal symptoms |
US4415546A (en) * | 1981-05-12 | 1983-11-15 | Janakiraman Ramachandran | Biologically active analogs of ACTH and radioimmuno assay therefor |
US4390531A (en) * | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
US4415547A (en) * | 1982-06-14 | 1983-11-15 | Sterling Drug Inc. | Sustained-release pharmaceutical tablet and process for preparation thereof |
JPS604120A (ja) * | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
US4826831A (en) * | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
GB8403360D0 (en) * | 1984-02-08 | 1984-03-14 | Erba Farmitalia | Pharmaceutical compositions |
EP0153105B1 (en) * | 1984-02-10 | 1992-09-09 | Benzon Pharma A/S | Diffusion coated multiple-units dosage form |
GB8414221D0 (en) * | 1984-06-04 | 1984-07-11 | Sterwin Ag | Unit dosage form |
SE8404467D0 (sv) * | 1984-09-06 | 1984-09-06 | Ferrosan Ab | Controlled-release medical preparations |
US4755386A (en) * | 1986-01-22 | 1988-07-05 | Schering Corporation | Buccal formulation |
US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
GB8705083D0 (en) * | 1987-03-04 | 1987-04-08 | Euro Celtique Sa | Spheroids |
US4927816A (en) * | 1987-08-20 | 1990-05-22 | Ester George C | Formulae and methods for sublingual ingestion of natural progesterone |
US5108995A (en) * | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
IT1227626B (it) * | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
US5073374A (en) * | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
DK469989D0 (da) * | 1989-09-22 | 1989-09-22 | Bukh Meditec | Farmaceutisk praeparat |
JP2542122B2 (ja) * | 1990-04-18 | 1996-10-09 | 旭化成工業株式会社 | 球状核、球形顆粒およびその製造方法 |
US5316772A (en) * | 1990-12-19 | 1994-05-31 | Solvay & Cie, S.A. (Societe Anonyme) | Bilayered oral pharmaceutical composition with pH dependent release |
US5223268A (en) * | 1991-05-16 | 1993-06-29 | Sterling Drug, Inc. | Low solubility drug-coated bead compositions |
WO1994018951A1 (en) * | 1993-02-23 | 1994-09-01 | Warner-Lambert Company | A process for the preparation of substantially alcohol free pharmaceutical compositions |
ZA949929B (en) * | 1993-12-23 | 1995-08-23 | Akzo Nobel Nv | Sugar-coated pharmaceutical dosage unit. |
US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
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1995
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1996
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- 1996-01-11 EE EE9600002A patent/EE03802B1/xx unknown
- 1996-01-11 SK SK49-96A patent/SK280484B6/sk not_active IP Right Cessation
- 1996-01-12 JP JP00368196A patent/JP3833292B2/ja not_active Expired - Lifetime
- 1996-01-15 CA CA002167254A patent/CA2167254A1/en not_active Abandoned
- 1996-01-15 ZA ZA96301A patent/ZA96301B/xx unknown
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- 1996-01-15 DK DK96300284T patent/DK0722720T3/da active
- 1996-01-15 SI SI9630070T patent/SI0722720T1/xx unknown
- 1996-01-15 AU AU40982/96A patent/AU705879B2/en not_active Expired
- 1996-01-15 MY MYPI96000145A patent/MY115786A/en unknown
- 1996-01-15 CO CO96001228A patent/CO4370096A1/es unknown
- 1996-01-15 RU RU96100843/14A patent/RU2152207C1/ru active
- 1996-01-15 AT AT96300284T patent/ATE185482T1/de active
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- 1996-01-15 ID IDP990833D patent/ID23996A/id unknown
- 1996-01-15 NZ NZ280826A patent/NZ280826A/en not_active IP Right Cessation
- 1996-01-16 NO NO19960191A patent/NO315307B1/no not_active IP Right Cessation
- 1996-01-16 IL IL11677296A patent/IL116772A/xx not_active IP Right Cessation
- 1996-01-16 HU HU9600090A patent/HU223781B1/hu active IP Right Grant
- 1996-01-16 TW TW085100468A patent/TW460301B/zh not_active IP Right Cessation
- 1996-01-16 BR BRPI9600100-3A patent/BR9600100B1/pt active IP Right Grant
- 1996-01-16 UA UA96010195A patent/UA37236C2/uk unknown
- 1996-01-16 CN CN96104096A patent/CN1106839C/zh not_active Expired - Lifetime
- 1996-01-16 TR TR96/00038A patent/TR199600038A2/xx unknown
- 1996-01-16 KR KR1019960000693A patent/KR100338581B1/ko not_active IP Right Cessation
- 1996-01-16 CZ CZ1996128A patent/CZ286102B6/cs not_active IP Right Cessation
- 1996-01-16 PL PL96312336A patent/PL183330B1/pl unknown
- 1996-01-16 FI FI960210A patent/FI117592B/fi not_active IP Right Cessation
- 1996-01-17 EG EG4796A patent/EG23687A/xx active
- 1996-04-10 US US08/631,876 patent/US5759576A/en not_active Expired - Lifetime
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1998
- 1998-09-21 HK HK98110778A patent/HK1009935A1/xx not_active IP Right Cessation
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1999
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