GB844772A - Granular pharmaceutical compositions and process for preparing same - Google Patents

Granular pharmaceutical compositions and process for preparing same

Info

Publication number
GB844772A
GB844772A GB756757A GB756757A GB844772A GB 844772 A GB844772 A GB 844772A GB 756757 A GB756757 A GB 756757A GB 756757 A GB756757 A GB 756757A GB 844772 A GB844772 A GB 844772A
Authority
GB
United Kingdom
Prior art keywords
sugar
gum
crystals
pharmaceutical compositions
finely divided
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB756757A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US844772XA priority Critical
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of GB844772A publication Critical patent/GB844772A/en
Application status is Expired legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Abstract

Pharmaceutical compositions which, on addition of water give solutions or uniform oral suspensions are prepared by coating coarse crystals of sugar having an average diameter of about 300 to 1200 microns such as of sucrose, lactose or dextrose with a water-soluble gum so that the surface of the crystals becomes sticky and applying to the sticky surfaces finely divided therapeutic agent. The sugar crystals may be mixed with a surface active agent and may be coated with finely divided sugar, before the gum coating. Successive coatings of gum and therapeutic agent may be applied with intermediate drying. Therapeutic agents include antibiotics, vitamins, minerals, antispasmodics, hypnotics, anticonvulsants, antihistamines, central nervous system stimulants, hormones; gums include pectin, acacia, agar, tragacanth, sodium alginate, methyl, carboxymethyl and sodium carboxymethyl cellulose and polyvinyl-pyrrolidone; solvents include butanol, isopropanol, carbon tetrachloride and ethylene dichloride.
GB756757A 1956-04-19 1957-03-07 Granular pharmaceutical compositions and process for preparing same Expired GB844772A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US844772XA true 1956-04-19 1956-04-19

Publications (1)

Publication Number Publication Date
GB844772A true GB844772A (en) 1960-08-17

Family

ID=22185205

Family Applications (1)

Application Number Title Priority Date Filing Date
GB756757A Expired GB844772A (en) 1956-04-19 1957-03-07 Granular pharmaceutical compositions and process for preparing same

Country Status (1)

Country Link
GB (1) GB844772A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2413090A1 (en) * 1975-07-18 1979-07-27 Abbott Lab Pharmaceutical Preparation is based ethylsuccinate erythromycin and its application against infections sensitive to erythromycin
GB2132890A (en) * 1983-01-06 1984-07-18 Andrew Macarthy Reynolds Oral veterinary drug
GB2159714A (en) * 1984-06-04 1985-12-11 Sterwin Ag Pharmaceutical composition of sparingly soluble medicament and method for its preparation
EP0164967A2 (en) * 1984-06-04 1985-12-18 Sterwin Ag. Pharmaceutical composition of sparingly soluble medicament and method for its preparation
EP0186090A2 (en) * 1984-12-24 1986-07-02 BASF Aktiengesellschaft Process for the preparation of an ascorbic-acid granulate
WO1986006626A1 (en) * 1985-05-08 1986-11-20 Eurand Italia S.P.A. Method of preparing an extemporaneous homogeneous microcapsule suspension
GB2167374B (en) * 1984-11-06 1989-06-01 Long Island University Aspirin or acetaminophen drug in bead form and process for preparing same.
US4867984A (en) * 1984-11-06 1989-09-19 Nagin K. Patel Drug in bead form and process for preparing same
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
EP1214892A1 (en) * 2000-12-15 2002-06-19 Quest International B.V. A moisture and oxygen stable composition and a process for obtaining said composition
WO2005110120A1 (en) * 2004-05-19 2005-11-24 Skymax Laboratories Pvt. Ltd. Pellets comprising protein and nutritional supplements and method for preparation thereof

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2413090A1 (en) * 1975-07-18 1979-07-27 Abbott Lab Pharmaceutical Preparation is based ethylsuccinate erythromycin and its application against infections sensitive to erythromycin
GB2132890A (en) * 1983-01-06 1984-07-18 Andrew Macarthy Reynolds Oral veterinary drug
EP0164967A3 (en) * 1984-06-04 1986-12-30 Sterwin Ag. Pharmaceutical composition of sparingly soluble medicament and method for its preparation
GB2159714A (en) * 1984-06-04 1985-12-11 Sterwin Ag Pharmaceutical composition of sparingly soluble medicament and method for its preparation
EP0164967A2 (en) * 1984-06-04 1985-12-18 Sterwin Ag. Pharmaceutical composition of sparingly soluble medicament and method for its preparation
US4717569A (en) * 1984-06-04 1988-01-05 Sterling Drug Inc. Unit dosage form of sparingly soluble medicaments
US4867984A (en) * 1984-11-06 1989-09-19 Nagin K. Patel Drug in bead form and process for preparing same
GB2167374B (en) * 1984-11-06 1989-06-01 Long Island University Aspirin or acetaminophen drug in bead form and process for preparing same.
EP0186090A3 (en) * 1984-12-24 1987-09-02 Basf Aktiengesellschaft Process for the preparation of an ascorbic-acid granulate
AU579691B2 (en) * 1984-12-24 1988-12-08 Basf Aktiengesellschaft Preparation of ascorbic acid granules
EP0186090A2 (en) * 1984-12-24 1986-07-02 BASF Aktiengesellschaft Process for the preparation of an ascorbic-acid granulate
US4800086A (en) * 1984-12-24 1989-01-24 Basf Aktiengesellschaft Preparation of ascorbic acid granules
WO1986006626A1 (en) * 1985-05-08 1986-11-20 Eurand Italia S.P.A. Method of preparing an extemporaneous homogeneous microcapsule suspension
US5008117A (en) * 1985-05-08 1991-04-16 Eurand Italia S.P.A. Formulation for preparing extemporaneous homogeneous microcapsule suspension
US5547948A (en) * 1995-01-17 1996-08-20 American Home Products Corporation Controlled release of steroids from sugar coatings
EP1214892A1 (en) * 2000-12-15 2002-06-19 Quest International B.V. A moisture and oxygen stable composition and a process for obtaining said composition
WO2002047492A2 (en) * 2000-12-15 2002-06-20 Quest International B.V. A moisture and oxygen stable composition and a process for obtaining said composition
WO2002047492A3 (en) * 2000-12-15 2002-11-21 Quest Int A moisture and oxygen stable composition and a process for obtaining said composition
US7018651B2 (en) 2000-12-15 2006-03-28 Quest International B.V. Moisture and oxygen stable composition and a process for obtaining said composition
WO2005110120A1 (en) * 2004-05-19 2005-11-24 Skymax Laboratories Pvt. Ltd. Pellets comprising protein and nutritional supplements and method for preparation thereof

Similar Documents

Publication Publication Date Title
CA948348A (en) Process for the preparation of 1,2-polybutadiene
GB1155628A (en) Production of Hydroxy-containing Epoxy Resin Esters and their use
CA996292A (en) Coating composition containing silane-titanate condensate and process for the preparation thereof
ZA7004322B (en) Improvements in or relating to apparatus for the electrostatic coating of objects with atomized solids particles
SE7410569A (en)
AT301982B (en) Gas wiping nozzle for adjusting the uniform thickness of a liquid-applied coating
IL35110A (en) New thiophene derivatives,process for the preparation thereof and herbicidal compositions containing the same and method of controlling the growth of weeds with said compositions
CA926711A (en) Process and apparatus for electrostatically spraying colorants, powders, fibrous materials or the like
ES464968A1 (en) Process for obtaining compositions coloran-tes or poor optical brighteners in dust.
DE2962099D1 (en) Powder coating, process for the preparation thereof and articles coated therewith
AU4543972A (en) Benzofurance derivatives, process for their preparatin and their use as optical brighteners
CA938416A (en) Process for the production of carbon fibers
DE2960567D1 (en) Plasma spray coating composition, method of coating articles and articles coated with the composition.
ES2028152T3 (en) Cationically adjusted pigment dispersion and paint coating.
GB1480575A (en) Process for the large-scale production of pre-coated microscope slides
IL37826D0 (en) Seed coating process and coated seeds
GB1522543A (en) Apparatus for applying preparation agents onto a filament bundle
ES484731A1 (en) Process for treating plant seeds
GB1381505A (en) Fluidized bed process and apparatus
US2693436A (en) Coating material for tablets and coated tablets
CA942596A (en) Process for coating flatlike surfaces
CA943826A (en) Coatings for fibrous materials, articles treated, and methods of application
CA920735A (en) Process for the production of shaped articles, particularly dental prostheses
CA921186A (en) Tetravinyl paint composition and painting process
CA941227A (en) Method of treating spent grain, new grain product and new use of spray drying