KR950704313A - 5-아릴인돌 유도체 및 세로토닌(5-ht₁)작용물질로서의 그의 용도(5-arylindole derivatives and their use as serotonin(5-ht₁)agonists) - Google Patents

5-아릴인돌 유도체 및 세로토닌(5-ht₁)작용물질로서의 그의 용도(5-arylindole derivatives and their use as serotonin(5-ht₁)agonists)

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Publication number
KR950704313A
KR950704313A KR1019950701729A KR19950701729A KR950704313A KR 950704313 A KR950704313 A KR 950704313A KR 1019950701729 A KR1019950701729 A KR 1019950701729A KR 19950701729 A KR19950701729 A KR 19950701729A KR 950704313 A KR950704313 A KR 950704313A
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KR
South Korea
Prior art keywords
alkyl
aryl
hydrogen
ring
membered
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KR1019950701729A
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English (en)
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KR0163371B1 (ko
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Publication of KR0163371B1 publication Critical patent/KR0163371B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
KR1019950701729A 1992-11-02 1993-10-19 5-아릴인돌 유도체 KR0163371B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97075892A 1992-11-02 1992-11-02
US7/970,758 1992-11-02
PCT/US1993/009790 WO1994010171A1 (en) 1992-11-02 1993-10-19 5-arylindole derivatives and their use as serotonin (5-ht1) agonists

Publications (2)

Publication Number Publication Date
KR950704313A true KR950704313A (ko) 1995-11-17
KR0163371B1 KR0163371B1 (ko) 1998-12-01

Family

ID=25517470

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950701729A KR0163371B1 (ko) 1992-11-02 1993-10-19 5-아릴인돌 유도체

Country Status (27)

Country Link
US (1) US5886008A (ko)
EP (2) EP0666858B1 (ko)
JP (1) JP2788551B2 (ko)
KR (1) KR0163371B1 (ko)
CN (1) CN1051313C (ko)
AT (1) ATE202102T1 (ko)
AU (1) AU685066B2 (ko)
BR (1) BR9307348A (ko)
CA (2) CA2148380C (ko)
CZ (1) CZ283001B6 (ko)
DE (1) DE69330351T2 (ko)
DK (1) DK0666858T3 (ko)
EG (1) EG20396A (ko)
ES (1) ES2157224T3 (ko)
FI (2) FI111257B (ko)
GR (1) GR3036579T3 (ko)
HU (1) HU222235B1 (ko)
IL (1) IL107386A (ko)
MY (1) MY109696A (ko)
NO (1) NO309652B1 (ko)
NZ (1) NZ257059A (ko)
PL (1) PL176091B1 (ko)
PT (1) PT666858E (ko)
RU (1) RU2134266C1 (ko)
TW (1) TW251284B (ko)
WO (1) WO1994010171A1 (ko)
ZA (1) ZA938137B (ko)

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US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
PE20030008A1 (es) 2001-06-19 2003-01-22 Bristol Myers Squibb Co Inhibidores duales de pde 7 y pde 4
DE60336576D1 (de) 2002-10-30 2011-05-12 Merck Sharp & Dohme Hemmer der akt aktivität
US20040102360A1 (en) * 2002-10-30 2004-05-27 Barnett Stanley F. Combination therapy
US7332508B2 (en) 2002-12-18 2008-02-19 Novo Nordisk A/S Substituted homopiperidine, piperidine or pyrrolidine derivatives
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DE10337184A1 (de) 2003-08-13 2005-03-10 Gruenenthal Gmbh Substituierte 3-Pyrrolidin-Indol-Derivate
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CA2984305C (en) 2015-04-29 2021-12-28 Janssen Pharmaceutica Nv Indolone compounds and their use as ampa receptor modulators
UY36654A (es) * 2015-04-29 2016-10-31 Janssen Pharmaceutica Nv Azabenzimidazoles con propiedades moduladoras del receptor ampa y composiciones farmacéuticas que los contienen
CN107810002B (zh) 2015-05-22 2021-01-05 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物
CN108349942B (zh) 2015-11-06 2021-03-30 豪夫迈·罗氏有限公司 用于治疗cns和相关疾病的二氢吲哚-2-酮衍生物
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JP6857651B2 (ja) 2015-11-06 2021-04-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｎｓ疾患の処置に有用なインドリン−２−オン誘導体
JP6857662B2 (ja) 2015-11-06 2021-04-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ インドリン−２−オン誘導体
CN111822047B (zh) * 2020-07-17 2022-05-27 曲阜师范大学 一种磁性介孔聚合离子液体负载催化合成吲哚类衍生物的方法

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Also Published As

Publication number Publication date
TW251284B (ko) 1995-07-11
CA2340999A1 (en) 1994-05-11
AU5329494A (en) 1994-05-24
EG20396A (en) 1999-02-28
BR9307348A (pt) 1999-05-11
DE69330351T2 (de) 2001-09-20
GR3036579T3 (en) 2001-12-31
NO309652B1 (no) 2001-03-05
FI111257B (fi) 2003-06-30
CZ110895A3 (en) 1995-11-15
MY109696A (en) 1997-04-30
PT666858E (pt) 2001-09-28
DK0666858T3 (da) 2001-08-27
ATE202102T1 (de) 2001-06-15
EP1094064A1 (en) 2001-04-25
DE69330351D1 (de) 2001-07-19
ZA938137B (en) 1995-05-02
CN1051313C (zh) 2000-04-12
NO951633L (no) 1995-04-28
PL176091B1 (pl) 1999-04-30
RU2134266C1 (ru) 1999-08-10
JPH07508759A (ja) 1995-09-28
IL107386A (en) 1999-03-12
NO951633D0 (no) 1995-04-28
EP0666858A1 (en) 1995-08-16
CZ283001B6 (cs) 1997-12-17
EP0666858B1 (en) 2001-06-13
NZ257059A (en) 1997-07-27
KR0163371B1 (ko) 1998-12-01
FI934825A (fi) 1994-05-03
ES2157224T3 (es) 2001-08-16
IL107386A0 (en) 1994-01-25
PL308669A1 (en) 1995-08-21
FI20002505A (fi) 2000-11-15
WO1994010171A1 (en) 1994-05-11
HU222235B1 (hu) 2003-05-28
CA2340999C (en) 2005-01-04
JP2788551B2 (ja) 1998-08-20
HUT66011A (en) 1994-08-29
CA2148380A1 (en) 1994-05-11
AU685066B2 (en) 1998-01-15
RU95109927A (ru) 1997-01-10
US5886008A (en) 1999-03-23
CA2148380C (en) 2001-08-14
FI934825A0 (fi) 1993-11-01
CN1094727A (zh) 1994-11-09

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