ATE230391T1 - Pyrrolidin derivate, anti-ulcus und antibakterielle arzneimittel - Google Patents
Pyrrolidin derivate, anti-ulcus und antibakterielle arzneimittelInfo
- Publication number
- ATE230391T1 ATE230391T1 AT98302660T AT98302660T ATE230391T1 AT E230391 T1 ATE230391 T1 AT E230391T1 AT 98302660 T AT98302660 T AT 98302660T AT 98302660 T AT98302660 T AT 98302660T AT E230391 T1 ATE230391 T1 AT E230391T1
- Authority
- AT
- Austria
- Prior art keywords
- ulcus
- group
- antibacterial drugs
- pyrrolidine derivatives
- integer
- Prior art date
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 229940124350 antibacterial drug Drugs 0.000 title 1
- FKCMADOPPWWGNZ-YUMQZZPRSA-N [(2r)-1-[(2s)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid Chemical compound CC(C)[C@H](N)C(=O)N1CCC[C@H]1B(O)O FKCMADOPPWWGNZ-YUMQZZPRSA-N 0.000 abstract 2
- 241000589989 Helicobacter Species 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10263097A JP4113602B2 (ja) | 1997-04-04 | 1997-04-04 | ピロリジン誘導体及び抗潰瘍剤、抗菌剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE230391T1 true ATE230391T1 (de) | 2003-01-15 |
Family
ID=14332567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98302660T ATE230391T1 (de) | 1997-04-04 | 1998-04-06 | Pyrrolidin derivate, anti-ulcus und antibakterielle arzneimittel |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5925667A (de) |
| EP (1) | EP0869118B1 (de) |
| JP (1) | JP4113602B2 (de) |
| KR (1) | KR19980081254A (de) |
| AT (1) | ATE230391T1 (de) |
| AU (1) | AU728542B2 (de) |
| CA (1) | CA2234134A1 (de) |
| DE (1) | DE69810373T2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141244B1 (en) * | 1992-03-02 | 2006-11-28 | Chiron Srl | Helicobacter pylori proteins useful for vaccines and diagnostics |
| ATE229978T1 (de) * | 1994-07-01 | 2003-01-15 | Chiron Corp | Helicobacter proteine und impstoffe |
| DK0909323T3 (da) * | 1996-01-04 | 2007-05-21 | Novartis Vaccines & Diagnostic | Helicobacter pylori-bakterioferritin |
| US6433186B1 (en) * | 2000-08-16 | 2002-08-13 | Astrazeneca Ab | Amidino derivatives and their use as thormbin inhibitors |
| US20050175629A1 (en) * | 2001-08-31 | 2005-08-11 | Giuseppe Del Giudice | Helicobacter pylori vaccination |
| JP4541662B2 (ja) * | 2003-05-29 | 2010-09-08 | オリザ油化株式会社 | 抗ピロリ菌組成物 |
| EP1886990A1 (de) * | 2006-08-01 | 2008-02-13 | Neuropharma S.A. | Phenylprenyletherderivate zur Behandlung kognitiver neurodegenerativer oder neuronaler Krankheiten oder Störungen |
| US20080142757A1 (en) * | 2006-12-13 | 2008-06-19 | E. I. Dupont De Nemours And Company | Alloyed nanophenes |
| US7476340B2 (en) * | 2006-12-13 | 2009-01-13 | E. I. Du Pont De Nemours & Company | Composition containing alloyed nanophene moieties |
| MX2011006913A (es) * | 2008-12-24 | 2011-11-18 | Ecobiotics Ltd | Extractos de planta de la especie acronychia y su uso. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3542788A (en) * | 1968-06-12 | 1970-11-24 | Searle & Co | 1-amino-5-phenyl-2-pyrrolepropionic acid and congeners |
| CH605793A5 (fr) * | 1974-03-05 | 1978-10-13 | Soc Et Scient Et Ind | Procédé de préparation de nouveaux N-(1benzylpyrrollidinil 2-alkyl) benzamides substitués |
| CH614709A5 (de) * | 1975-09-25 | 1979-12-14 | Ciba Geigy Ag | |
| JPS5473780A (en) * | 1977-11-15 | 1979-06-13 | Shionogi & Co Ltd | Novel benzamide derivative |
| JPS5695165A (en) * | 1979-12-28 | 1981-08-01 | Sato Yoshio | Preparation of substituted benzoic acid amide |
| JPH01168678A (ja) * | 1987-12-24 | 1989-07-04 | Teikoku Chem Ind Corp Ltd | ベンズアミド誘導体 |
| JP2700910B2 (ja) * | 1989-02-07 | 1998-01-21 | 帝国化学産業株式会社 | ベンズアミド誘導体 |
| JPH05239005A (ja) * | 1992-02-28 | 1993-09-17 | Kitsuen Kagaku Kenkyu Zaidan | Ｎ−（２−アミノエチル）ベンズアミド類およびその新規中間体 |
| JP3081773B2 (ja) * | 1995-03-31 | 2000-08-28 | 株式会社資生堂 | Ｎ−アシルピペラジン誘導体及び抗菌剤、抗潰瘍剤 |
| JP3065506B2 (ja) * | 1995-04-03 | 2000-07-17 | 株式会社資生堂 | ピラゾリジン誘導体及びラジカルスカベンジャー、脳梗塞抑制剤、脳浮腫抑制剤 |
-
1997
- 1997-04-04 JP JP10263097A patent/JP4113602B2/ja not_active Expired - Fee Related
-
1998
- 1998-04-02 US US09/053,659 patent/US5925667A/en not_active Expired - Lifetime
- 1998-04-03 AU AU60633/98A patent/AU728542B2/en not_active Ceased
- 1998-04-03 CA CA002234134A patent/CA2234134A1/en not_active Abandoned
- 1998-04-03 KR KR1019980012683A patent/KR19980081254A/ko not_active Withdrawn
- 1998-04-06 DE DE69810373T patent/DE69810373T2/de not_active Expired - Lifetime
- 1998-04-06 AT AT98302660T patent/ATE230391T1/de not_active IP Right Cessation
- 1998-04-06 EP EP98302660A patent/EP0869118B1/de not_active Expired - Lifetime
- 1998-12-03 US US09/204,273 patent/US6043243A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6043243A (en) | 2000-03-28 |
| EP0869118A1 (de) | 1998-10-07 |
| JP4113602B2 (ja) | 2008-07-09 |
| AU6063398A (en) | 1998-10-08 |
| DE69810373T2 (de) | 2003-10-30 |
| CA2234134A1 (en) | 1998-10-04 |
| KR19980081254A (ko) | 1998-11-25 |
| AU728542B2 (en) | 2001-01-11 |
| DE69810373D1 (de) | 2003-02-06 |
| US5925667A (en) | 1999-07-20 |
| EP0869118B1 (de) | 2003-01-02 |
| JPH10279556A (ja) | 1998-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |