KR950016777A - 과실 폴리페놀과 그의 제조방법, 산화방지제, 혈압강하제, 항변이원성 작용제, 알레르기 억제제 및 항우식제 - Google Patents
과실 폴리페놀과 그의 제조방법, 산화방지제, 혈압강하제, 항변이원성 작용제, 알레르기 억제제 및 항우식제 Download PDFInfo
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- KR950016777A KR950016777A KR1019940024178A KR19940024178A KR950016777A KR 950016777 A KR950016777 A KR 950016777A KR 1019940024178 A KR1019940024178 A KR 1019940024178A KR 19940024178 A KR19940024178 A KR 19940024178A KR 950016777 A KR950016777 A KR 950016777A
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- fruit
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- rosaceae
- apple
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- 235000013824 polyphenols Nutrition 0.000 title claims abstract description 17
- 150000008442 polyphenolic compounds Chemical class 0.000 title claims abstract description 16
- 235000013399 edible fruits Nutrition 0.000 title claims abstract 29
- 239000002220 antihypertensive agent Substances 0.000 title claims abstract 4
- 239000002592 antimutagenic agent Substances 0.000 title claims abstract 4
- 239000003963 antioxidant agent Substances 0.000 title claims abstract 4
- 229940030600 antihypertensive agent Drugs 0.000 title claims 3
- 239000003112 inhibitor Substances 0.000 title claims 3
- 230000000172 allergic effect Effects 0.000 title 1
- 230000000675 anti-caries Effects 0.000 title 1
- 208000010668 atopic eczema Diseases 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 241000220222 Rosaceae Species 0.000 claims abstract 16
- 235000004789 Rosa xanthina Nutrition 0.000 claims abstract 15
- 230000002401 inhibitory effect Effects 0.000 claims abstract 7
- 230000003078 antioxidant effect Effects 0.000 claims abstract 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract 4
- 239000003795 chemical substances by application Substances 0.000 claims abstract 3
- 244000144730 Amygdalus persica Species 0.000 claims 7
- 241000220225 Malus Species 0.000 claims 7
- 235000006040 Prunus persica var persica Nutrition 0.000 claims 7
- 241000220324 Pyrus Species 0.000 claims 7
- 235000011430 Malus pumila Nutrition 0.000 claims 6
- 235000015103 Malus silvestris Nutrition 0.000 claims 6
- 235000014443 Pyrus communis Nutrition 0.000 claims 6
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000000340 Glucosyltransferases Human genes 0.000 claims 1
- 108010055629 Glucosyltransferases Proteins 0.000 claims 1
- 108010003272 Hyaluronate lyase Proteins 0.000 claims 1
- 102000001974 Hyaluronidases Human genes 0.000 claims 1
- 235000021016 apples Nutrition 0.000 claims 1
- 229940088598 enzyme Drugs 0.000 claims 1
- 229960002773 hyaluronidase Drugs 0.000 claims 1
- 230000007886 mutagenicity Effects 0.000 claims 1
- 231100000299 mutagenicity Toxicity 0.000 claims 1
- 235000021017 pears Nutrition 0.000 claims 1
- 238000000605 extraction Methods 0.000 abstract 2
- 108010043797 4-alpha-glucanotransferase Proteins 0.000 abstract 1
- 230000000170 anti-cariogenic effect Effects 0.000 abstract 1
- 230000002790 anti-mutagenic effect Effects 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 102100039604 mRNA guanylyltransferase Human genes 0.000 abstract 1
- 108010026228 mRNA guanylyltransferase Proteins 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- -1 lipid peroxide Chemical class 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 4
- 238000002835 absorbance Methods 0.000 description 3
- 235000010724 Wisteria floribunda Nutrition 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/02—Antioxidant
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/304—Foods, ingredients or supplements having a functional effect on health having a modulation effect on allergy and risk of allergy
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고, 또 그 획분이 정제되어서 이루어지는 과실 폴리페놀. 장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고 또 정제되어서 이루어지는, 폴리페놀 획분을 유효성분으로 하는 산화방지제, 혈압강하제, 항변이원성 작용제, 알레르기 억제제 및 항우식제. 각종의 생리작용,특히 항산화성 ACE저해활성, 항변이원성 작용, 미알루로니다제 저해활
성, GTase활성 저해작용을 가지는 과실 폴리페놀 획분을 제공할 수가 있다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 사과 미숙과(未熟果) 폴리페놀의 파장가변(波長可變) 크로마토그람파 각 피크의 자외부(紫外部)흡수 스펙트럼의 비교를 나타내는 그래프,
제2도는 사과「후지」추출액을 반응계에 첨가한 때의, 1주간 후에 있어서의 생성 과산화 지질량(脂質量)(흡광도 500nm 값)과 첨가농도의 관계를 나타내는 그래프,
제3도는 사과「후지」 각 劃分(획분)을 반응계에 첨가한 때의, 1주간 후에 있어서의 생성 과산화 지질량(흡광도 500nm 값)과 첨가농도의 관계를 나타내는 그래프,
제4도는 폴리페놀 화합물을 반응계에 첨가한 때의, 1주간 후에 있어서의 생성 과산화 지질량(홉광도 500nm 값)의 비교를 나타내는 그래프,
제5도는 각 사과 폴리페놀 획분을 반응계에 첨가한 때의, 1주간 후에 있어서의 생성 과산화 지질량(흡광도 500nm 값)과 첨가농도의 관계를 나타내는 그래프.
Claims (14)
- 장미과에 속하는 과실의 미숙과에서 착즙 및/또는 추출되고, 또 그의 획분이 정제되어서 이루어짐을 특징으로 하는 과실 폴리페놀.
- 제1항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 과실 폴리페놀.
- 장미과에 속하는 과실의 미숙과실을 착즙 및/또는 추출하고, 이어서 이 착즙과즙 및/또는 추출액에서 폴리페놀 획분을 정제하는 것을 특징으로 하는 과실 폴리페놀의 제조방법.
- 제3항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 과실 폴리페놀의 제조방법.
- 장미과에 속하는 과실의 미숙과에서 착즙 및/또는 추출되고 또 정제되어서 이루어지는, 폴리페놀 획분을 유효성분으로 하는 산화방지제.
- 제5항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 산화방지제.
- 장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고 또 정제되어서 이루어지는, 안디오텐신 I 변환효소 저해작용을 가지는 폴리페놀 획분을 유효성분으로 하는 혈압강하제.
- 제7항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 혈압강하제.
- 장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고 또 정제되민서 이루어지는, 변이원성 억제작용을 가지는 폴리페놀 획분을 유효성분으로 하는 항변이원성 작용제.
- 제9항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 항변이원성 작용제.
- 장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고 또 정제되어서 이루어지는, 히알루로니다제 저해작용을 가지는 폴리페놀 획분을 유효성분으로 하는 알레르기 억제제.
- 제11항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 알레르기 억제제.
- 장미과에 속하는 과실의 미숙과실에서 착즙 및/또는 추출되고 또 정제되어서 이루어지는, 글루코실트란스페라제 저해작용을 가지는 폴리페놀 획분을 유효성분으로 하는 항우식제.
- 제13항에 있어서, 장미과에 속하는 과실이 사과, 배 또는 복숭아인 항우식제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30563293 | 1993-12-06 | ||
JP93-305632 | 1993-12-06 | ||
JP94-24435 | 1994-02-22 | ||
JP2443594 | 1994-02-22 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020000047780A Division KR100305116B1 (ko) | 1993-12-06 | 2000-08-18 | 과실의 폴리페놀 혼합물 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR950016777A true KR950016777A (ko) | 1995-07-20 |
KR100302514B1 KR100302514B1 (ko) | 2001-11-22 |
Family
ID=26361940
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940024178A KR100302514B1 (ko) | 1993-12-06 | 1994-09-26 | 과실의폴리페놀혼합물의제조방법 |
KR1020000047780A KR100305116B1 (ko) | 1993-12-06 | 2000-08-18 | 과실의 폴리페놀 혼합물 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020000047780A KR100305116B1 (ko) | 1993-12-06 | 2000-08-18 | 과실의 폴리페놀 혼합물 |
Country Status (9)
Country | Link |
---|---|
US (2) | US5932623A (ko) |
EP (1) | EP0657169B1 (ko) |
KR (2) | KR100302514B1 (ko) |
CN (1) | CN1051089C (ko) |
AT (1) | ATE224722T1 (ko) |
AU (1) | AU683892B2 (ko) |
CA (1) | CA2128293C (ko) |
DE (1) | DE69431423T2 (ko) |
NZ (1) | NZ264067A (ko) |
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EP0727218A3 (en) * | 1995-02-10 | 1997-01-15 | Suntory Ltd | Anti-allergic compositions containing God-type ellagitannin as the active ingredient |
EP0727217A3 (en) * | 1995-02-10 | 1997-01-15 | Suntory Ltd | Pharmaceutical and cosmetic compositions containing God-type ellagitannin as an active ingredient |
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US6261565B1 (en) | 1996-03-13 | 2001-07-17 | Archer Daniels Midland Company | Method of preparing and using isoflavones |
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US6423743B1 (en) | 1996-04-02 | 2002-07-23 | Mars Incorporated | Cocoa extract compounds and methods for making and using the same |
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FR2799121B1 (fr) * | 1999-10-01 | 2004-02-13 | Fabre Pierre Dermo Cosmetique | Extraits de branches de pommiers utiles en dermocosmetologie et leur procede de preparation |
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US6509054B1 (en) * | 2000-05-05 | 2003-01-21 | American Fruits And Flavors | Food additives having enlarged concentration of phenolics extracted from fruits, and process of obtaining the same |
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DE10053496A1 (de) * | 2000-10-27 | 2002-05-08 | Peter Fuerst | Zusammensetzungen enthaltend Flavonoide und Phloridzin oder Phloretin |
FR2820738B1 (fr) | 2001-02-15 | 2003-05-16 | Agronomique Inst Nat Rech | Procede d'extraction, de fractionnement et de purification de composes polyphenoliques issus d'ecarts de triage de vegetaux frais utilisant une resine a haut rendement d'adsorption et d'elution |
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AU2003236187A1 (en) * | 2002-03-29 | 2003-10-13 | Yasuyuki Shirota | Drugs including anticancer agents and immunopotentiators and health foods and drinks |
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IT201900019781A1 (it) | 2019-10-25 | 2021-04-25 | Herbal E Antioxidant Derivatives Srl Ed In Forma Abbreviata H&Ad Srl | Processo di estrazione di mele da dirado o di residui di lavorazione delle mele ed estratti ottenuti |
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US2823126A (en) * | 1956-01-03 | 1958-02-11 | Sharples Corp | Method of producing juices from vegetables including fruits |
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DE3509892C2 (de) * | 1985-03-19 | 1994-04-21 | Westfalia Separator Ag | Verfahren zum Nachklären und Stabilisieren von Polyphenole und/oder Eiweißstoffe enthaltenden Flüssigkeiten und Getränken, insbesondere von Bier |
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WO1988009178A1 (en) * | 1987-05-18 | 1988-12-01 | Vladimir Badmajew | Pharmaceutical preparation |
DE8809178U1 (de) * | 1988-07-18 | 1988-09-01 | Huning-Wesseler, Walter, 4520 Melle | Drescheinrichtung für vorzugsweise selbstfahrende Mähdrescher |
US5525341A (en) * | 1992-10-09 | 1996-06-11 | Jlb, Inc. | Partially purified cranberry anti-adhesion activity |
-
1994
- 1994-07-18 CA CA002128293A patent/CA2128293C/en not_active Expired - Fee Related
- 1994-07-20 EP EP94401669A patent/EP0657169B1/en not_active Expired - Lifetime
- 1994-07-20 AT AT94401669T patent/ATE224722T1/de not_active IP Right Cessation
- 1994-07-20 DE DE69431423T patent/DE69431423T2/de not_active Expired - Lifetime
- 1994-07-22 NZ NZ264067A patent/NZ264067A/en not_active IP Right Cessation
- 1994-08-09 AU AU68996/94A patent/AU683892B2/en not_active Expired
- 1994-08-18 CN CN94115048A patent/CN1051089C/zh not_active Expired - Lifetime
- 1994-09-26 KR KR1019940024178A patent/KR100302514B1/ko not_active IP Right Cessation
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1995
- 1995-11-09 US US08/555,729 patent/US5932623A/en not_active Expired - Lifetime
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NZ264067A (en) | 1996-05-28 |
KR100305116B1 (ko) | 2001-09-24 |
US5932623A (en) | 1999-08-03 |
AU6899694A (en) | 1994-10-13 |
CA2128293C (en) | 2002-09-03 |
DE69431423T2 (de) | 2003-08-07 |
EP0657169A1 (en) | 1995-06-14 |
ATE224722T1 (de) | 2002-10-15 |
CN1051089C (zh) | 2000-04-05 |
KR100302514B1 (ko) | 2001-11-22 |
DE69431423D1 (de) | 2002-10-31 |
CN1121924A (zh) | 1996-05-08 |
EP0657169B1 (en) | 2002-09-25 |
CA2128293A1 (en) | 1995-06-07 |
AU683892B2 (en) | 1997-11-27 |
US5994413A (en) | 1999-11-30 |
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