KR940701256A - 판토프라졸 함유 약제의 경구 투여 형태 - Google Patents

판토프라졸 함유 약제의 경구 투여 형태

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Publication number
KR940701256A
KR940701256A KR1019930703898A KR930703898A KR940701256A KR 940701256 A KR940701256 A KR 940701256A KR 1019930703898 A KR1019930703898 A KR 1019930703898A KR 930703898 A KR930703898 A KR 930703898A KR 940701256 A KR940701256 A KR 940701256A
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South Korea
Prior art keywords
resistant
drug
physiologically
hydroxypropylmethylcellulose
polyvinylpyrrolidone
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KR1019930703898A
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English (en)
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KR100254021B1 (ko
Inventor
랑고 디트리히
하르트무트 네이
Original Assignee
허버트 서키, 울리히 울프
빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4218617&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR940701256(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 허버트 서키, 울리히 울프, 빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하 filed Critical 허버트 서키, 울리히 울프
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Publication of KR100254021B1 publication Critical patent/KR100254021B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

본 발명은 코어, 중간물질 층 및 위액에 내성을 갖는 최외층으로 구성된 판토프라졸용 경구 투여 형태에 관한 것이다.

Description

판토프라졸 함유 약제의 경구 투여 형태
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. -활성 화합물 또는 이의 생리학적으로 내성을 갖는 염이 하나이상의 결합제, 충전제, 필요할 경우 다른 정제 보조제, 및 필요할 경우, 하나이상의 생리학적으로 내성을 갖는 염기성 무기 화합물과의 혼합물로서 존재하는 코어; -상기 코어를 둘러싸고 있는 하나이상의 불활성, 수용성 중간물질 층, 및 -위액에 내성을 갖는 최외층으로 구성되고, 위액에 내성이 있으며, 경구 투여되는 펠릿 또는 정제 형태의 약물에 있어서, 상기 코어내에 판토프라졸이 활성 화합물로서 사용되고, 폴리비닐피롤리돈 및/또는 히드록시프로필메틸셀룰로서가 결합제로서 사용되고, 필요할 경우, 만니톨이 충전제로서 사용되는 것을 특징으로 하는 약물.
  2. 제1항에 있어서, 폴리비닐피롤린돈 및/또는 히드록시프로필메틸셀룰로스가 결합제로서 사용되고, 만니톨이 충전제로서 사용되는 것을 특징으로 하는 정제 형태의 약물.
  3. 제1항에 있어서, 폴리비닐피롤리돈 및/또는 히드록시프로필메틸셀룰로스가 결합제로서 사용되는 것을 특징으로 하는 펠릿 형태의 약물.
  4. 제1항 내지 제3항중 어느 한 항에 있어서, 판토프라졸-나트륨이 생리학적으로 내성이 있는 활성 화합물 염으로서 사용되는 것을 특징으로 하는 약물.
  5. 제1항 내지 제3항 중 어느 한 항에 있어서, 약산의 약물학적으로 내성을 갖는 알칼리 금속염, 알칼리 토금속염 또는 토류 금속염 또는 알칼리 토금속 또는 토류 금속의 약물학적으로 내성을 갖는 수산화물 또는 산화물을 생리학적으로 내성을 갖는 염기성 무기 화합물로 사용하는 것을 특징으로 하는 약제.
  6. 제1항 내지 제3항중 어느 한 항에 있어서, 탄산나트륨을 생리학적으로 내성을 갖는 염기성 무기 화합물로 사용하는 것을 특징으로 하는 약물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930703898A 1991-06-17 1992-06-13 판토프라졸 함유 약제의 경구 투여 형태 KR100254021B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH1788/91-0 1991-06-17
CH178891 1991-06-17
PCT/EP1992/001341 WO1992022284A1 (de) 1991-06-17 1992-06-13 Pantoprazol enthaltende orale darreichungsformen

Publications (2)

Publication Number Publication Date
KR940701256A true KR940701256A (ko) 1994-05-28
KR100254021B1 KR100254021B1 (ko) 2000-05-01

Family

ID=4218617

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930703898A KR100254021B1 (ko) 1991-06-17 1992-06-13 판토프라졸 함유 약제의 경구 투여 형태

Country Status (34)

Country Link
US (1) US5997903A (ko)
EP (2) EP0589981B1 (ko)
JP (1) JP3338052B2 (ko)
KR (1) KR100254021B1 (ko)
CN (1) CN1037932C (ko)
AT (1) ATE144416T1 (ko)
AU (1) AU683411B2 (ko)
BG (1) BG61796B1 (ko)
CA (2) CA2109697C (ko)
CZ (1) CZ281697B6 (ko)
DE (2) DE4219390A1 (ko)
DK (1) DK0589981T3 (ko)
ES (1) ES2096080T3 (ko)
FI (1) FI101598B1 (ko)
GR (1) GR3022154T3 (ko)
HK (1) HK1005851A1 (ko)
HR (1) HRP920162B1 (ko)
IE (1) IE77640B1 (ko)
IL (1) IL102096A (ko)
LV (1) LV11982B (ko)
MX (1) MX9202961A (ko)
NO (1) NO303714B1 (ko)
NZ (1) NZ243147A (ko)
PL (1) PL169951B1 (ko)
RO (1) RO117502B1 (ko)
RU (1) RU2089180C1 (ko)
SI (1) SI9200111A (ko)
SK (1) SK278566B6 (ko)
TW (1) TW224429B (ko)
UA (1) UA32525C2 (ko)
WO (1) WO1992022284A1 (ko)
YU (1) YU48263B (ko)
ZA (1) ZA924386B (ko)
ZW (1) ZW9392A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
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KR100657835B1 (ko) * 1998-08-18 2006-12-15 알타나 파마 아게 판토프라졸의 신규한 염 형태

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