ES2162874T3 - Composicion farmaceutica para hacer llegar medicamentos hasta el colon. - Google Patents

Composicion farmaceutica para hacer llegar medicamentos hasta el colon.

Info

Publication number
ES2162874T3
ES2162874T3 ES95103386T ES95103386T ES2162874T3 ES 2162874 T3 ES2162874 T3 ES 2162874T3 ES 95103386 T ES95103386 T ES 95103386T ES 95103386 T ES95103386 T ES 95103386T ES 2162874 T3 ES2162874 T3 ES 2162874T3
Authority
ES
Spain
Prior art keywords
colon
pharmaceutical composition
delivery system
polymer layer
come until
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95103386T
Other languages
English (en)
Inventor
Wantanee Phuapradit
Aruna Railkar
Navnit Hargovindas Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2162874T3 publication Critical patent/ES2162874T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Abstract

UN SISTEMA NUEVO DE APLICACION DE MEDICAMENTO AL COLON QUE COMPRENDE TRES PARTES: (1) UN RECUBRIMIENTO ENTERICO PARA PREVENIR LA PENETRACION DE FLUIDOS GASTRICOS EN EL SISTEMA DE APLICACION, POR TANTO EVITANDO CUALQUIER LIBERACION DEL MEDICAMENTE EN EL ESTOMAGO; (2) UNA CAPA DE POLIMERO EROSIONABLE LA CUAL ESTA EXPUESTA Y SE EROSIONA GRADUALMENTE DURANTE EL TRANSITO POR EL TRACTO INTESTINAL SUPERIOR; Y (3) UN NUCLEO, QUE ES UNA TABLETA CONVENCIONAL O CONGLOMERADA QUE CONTIENE INGREDIENTE/S ACTIVOS, LOS CUALES SE DESINTEGRAN CONVENIENTEMENTE Y LIBERAN CONSECUENTEMENTE EL MEDICAMENTO EN LA ZONA ASIGNADA, EL COLON, DESPUES DE LA EROSION DE LA CAPA DE POLIMERO EROSIONABLE.
ES95103386T 1994-03-23 1995-03-09 Composicion farmaceutica para hacer llegar medicamentos hasta el colon. Expired - Lifetime ES2162874T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/217,344 US5482718A (en) 1994-03-23 1994-03-23 Colon-targeted delivery system

Publications (1)

Publication Number Publication Date
ES2162874T3 true ES2162874T3 (es) 2002-01-16

Family

ID=22810676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95103386T Expired - Lifetime ES2162874T3 (es) 1994-03-23 1995-03-09 Composicion farmaceutica para hacer llegar medicamentos hasta el colon.

Country Status (15)

Country Link
US (1) US5482718A (es)
EP (1) EP0673645B1 (es)
JP (1) JP2774080B2 (es)
CN (1) CN1112417A (es)
AT (1) ATE205705T1 (es)
AU (1) AU696943B2 (es)
CA (1) CA2142653A1 (es)
DE (1) DE69522729T2 (es)
DK (1) DK0673645T3 (es)
ES (1) ES2162874T3 (es)
NZ (1) NZ270737A (es)
PH (1) PH31334A (es)
PT (1) PT673645E (es)
RU (1) RU2138251C1 (es)
ZA (1) ZA952169B (es)

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US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US7220430B2 (en) * 2000-01-27 2007-05-22 Tanabe Seiyaku Co., Ltd. Sustained-release preparation and process for producing the same
JPWO2001078681A1 (ja) 2000-04-17 2004-01-08 山之内製薬株式会社 薬物動態学的な薬物相互作用を回避する薬物送達システム及びその方法
IT1318625B1 (it) * 2000-07-14 2003-08-27 Roberto Valducci Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
MXPA03008293A (es) * 2001-03-13 2003-12-11 Penwest Pharmaceuticals Co Formas de dosis cronoterapeuticas.
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
AR036797A1 (es) 2001-10-15 2004-10-06 Ferring Bv Un metodo para preparar una composicion farmaceutica que comprende acido 5-aminosalicilico para utilizar en el tratamiento de colitis ulcerosa y enfermedades de crohn
GB0124953D0 (en) * 2001-10-17 2001-12-05 Novartis Ag Organic Compounds
EP1455751A1 (en) * 2001-12-20 2004-09-15 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
JP2003238393A (ja) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd 施錠性が改善された錠剤及びその製造方法
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
CA2520197A1 (en) * 2003-04-23 2004-11-04 Ferring B.V. Sachet for a pharmaceutical composition
JP4790597B2 (ja) 2003-04-24 2011-10-12 ヤゴテック アーゲー 規定されたコア幾何学的配置を有する遅延放出錠
EP1667658A2 (en) * 2003-09-03 2006-06-14 Mallinckrodt Inc. Granular sustained release preparation and production thereof
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US20050118267A1 (en) * 2003-09-19 2005-06-02 Penwest Pharmaceuticals Co. Chronotherapeutic dosage forms
JP2007505921A (ja) * 2003-09-19 2007-03-15 ペンウェスト ファーマシューティカルズ カンパニー 遅延放出剤形
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
DE102004026706A1 (de) * 2004-05-28 2005-12-15 Merck Patent Gmbh Orale Darreichungsform enthaltend probiotische Bakterien
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
FR2891459B1 (fr) * 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
WO2008015018A1 (en) 2006-08-03 2008-02-07 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
US20090028944A1 (en) * 2007-07-16 2009-01-29 Balaji Sathurappan Pharmaceutical compositions comprising mesalamine
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
GB0900350D0 (en) * 2009-01-09 2009-02-11 Cambridge Entpr Ltd Formulations of viable bacteria for oral delivery
CN102784203A (zh) * 2011-05-20 2012-11-21 上海凯宝药业股份有限公司 一种痰热清片剂及其制备方法
WO2013035081A2 (de) 2011-09-07 2013-03-14 JÄNISCH, Melisa Optimale formulierung zur freisetzung eines wirkstoffes im dickdarm
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
CN102319218B (zh) * 2011-09-22 2014-10-01 贝沃特医药技术(上海)有限公司 一种治疗肠道疾病的药物缓控释微粒制剂及其制备方法
AU2014239683B2 (en) 2013-03-15 2018-05-17 Allergan Pharmaceuticals International Limited Mesalamine pharmaceutical composition with multiple dosage elements for reduced delivery variability
US10182993B2 (en) 2015-04-06 2019-01-22 Patheon Softgels Inc. Compositions for colonic delivery of drugs
US11596607B2 (en) 2017-04-18 2023-03-07 Actorious Innovations And Research Pvt. Ltd. Polymer based formulation for release of drugs and bioactives at specific GIT sites
US11590161B2 (en) 2018-08-13 2023-02-28 Viscera Labs, Inc. Therapeutic composition and methods
US11524029B2 (en) 2018-08-13 2022-12-13 Viscera Labs, Inc. Therapeutic composition and methods
EP3662902A1 (en) * 2018-12-07 2020-06-10 Tillotts Pharma AG Colonic drug delivery formulation
WO2021163007A1 (en) * 2020-02-12 2021-08-19 Viscera Labs, Inc. Therapeutic composition and methods
US11896719B2 (en) * 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

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FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
US4668517A (en) * 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
IT1260505B (it) * 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon

Also Published As

Publication number Publication date
DK0673645T3 (da) 2001-11-12
ZA952169B (en) 1995-09-26
CN1112417A (zh) 1995-11-29
ATE205705T1 (de) 2001-10-15
EP0673645A3 (en) 1996-07-24
PH31334A (en) 1998-07-06
NZ270737A (en) 1996-11-26
PT673645E (pt) 2002-03-28
DE69522729T2 (de) 2002-07-04
DE69522729D1 (de) 2001-10-25
JPH07277958A (ja) 1995-10-24
JP2774080B2 (ja) 1998-07-09
AU696943B2 (en) 1998-09-24
EP0673645A2 (en) 1995-09-27
RU2138251C1 (ru) 1999-09-27
AU1488295A (en) 1995-10-05
EP0673645B1 (en) 2001-09-19
CA2142653A1 (en) 1995-09-24
US5482718A (en) 1996-01-09

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