DE69522729D1 - Arzneimittel zum Wirkstoff - Targetting in den Dickdarm - Google Patents

Arzneimittel zum Wirkstoff - Targetting in den Dickdarm

Info

Publication number
DE69522729D1
DE69522729D1 DE69522729T DE69522729T DE69522729D1 DE 69522729 D1 DE69522729 D1 DE 69522729D1 DE 69522729 T DE69522729 T DE 69522729T DE 69522729 T DE69522729 T DE 69522729T DE 69522729 D1 DE69522729 D1 DE 69522729D1
Authority
DE
Germany
Prior art keywords
active ingredient
targeting
drugs
colon
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69522729T
Other languages
English (en)
Other versions
DE69522729T2 (de
Inventor
Wantanee Phuapradit
Aruna Railkar
Navnit Hargovindas Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE69522729D1 publication Critical patent/DE69522729D1/de
Publication of DE69522729T2 publication Critical patent/DE69522729T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radar Systems Or Details Thereof (AREA)
DE69522729T 1994-03-23 1995-03-09 Arzneimittel zum Wirkstoff - Targetting in den Dickdarm Expired - Fee Related DE69522729T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/217,344 US5482718A (en) 1994-03-23 1994-03-23 Colon-targeted delivery system

Publications (2)

Publication Number Publication Date
DE69522729D1 true DE69522729D1 (de) 2001-10-25
DE69522729T2 DE69522729T2 (de) 2002-07-04

Family

ID=22810676

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522729T Expired - Fee Related DE69522729T2 (de) 1994-03-23 1995-03-09 Arzneimittel zum Wirkstoff - Targetting in den Dickdarm

Country Status (15)

Country Link
US (1) US5482718A (de)
EP (1) EP0673645B1 (de)
JP (1) JP2774080B2 (de)
CN (1) CN1112417A (de)
AT (1) ATE205705T1 (de)
AU (1) AU696943B2 (de)
CA (1) CA2142653A1 (de)
DE (1) DE69522729T2 (de)
DK (1) DK0673645T3 (de)
ES (1) ES2162874T3 (de)
NZ (1) NZ270737A (de)
PH (1) PH31334A (de)
PT (1) PT673645E (de)
RU (1) RU2138251C1 (de)
ZA (1) ZA952169B (de)

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AU5775398A (en) * 1996-12-17 1998-07-15 Poli Industria Chimica S.P.A. Site-specific controlled release dosage formulation for mesalamine
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US7220430B2 (en) * 2000-01-27 2007-05-22 Tanabe Seiyaku Co., Ltd. Sustained-release preparation and process for producing the same
WO2001078681A1 (fr) 2000-04-17 2001-10-25 Yamanouchi Pharmaceutical Co., Ltd. Systeme d'administration de medicament empechant l'interaction pharmacocinetique entre les medicaments et procede correspondant
IT1318625B1 (it) * 2000-07-14 2003-08-27 Roberto Valducci Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
CA2359812C (en) * 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
JP5005157B2 (ja) * 2001-03-13 2012-08-22 ペンウェスト ファーマシューティカルズ カンパニー 時間治療（ｃｈｒｏｎｏｔｈｅｒａｐｅｕｔｉｃ）投与形態
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
AR036797A1 (es) 2001-10-15 2004-10-06 Ferring Bv Un metodo para preparar una composicion farmaceutica que comprende acido 5-aminosalicilico para utilizar en el tratamiento de colitis ulcerosa y enfermedades de crohn
GB0124953D0 (en) * 2001-10-17 2001-12-05 Novartis Ag Organic Compounds
CA2470636A1 (en) * 2001-12-20 2003-07-03 Pharmacia Corporation Zero-order sustained released dosage forms and method of making the same
JP2003238393A (ja) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd 施錠性が改善された錠剤及びその製造方法
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
JP2007523664A (ja) 2003-04-23 2007-08-23 フェリング ベスローテン フェンノートシャップ 医薬組成物用サシェ
KR101192722B1 (ko) 2003-04-24 2012-10-18 자고텍 아게 정해진 핵 위치를 가지는 서방성 정제
US7825106B2 (en) * 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US7790201B2 (en) * 2003-09-03 2010-09-07 Mallinckrodt Inc. Granular sustained release preparation and production thereof
WO2005027878A1 (en) * 2003-09-19 2005-03-31 Penwest Pharmaceuticals Co. Delayed released dosage forms
MXPA06003101A (es) * 2003-09-19 2006-06-20 Penwest Pharmaceuticals Co Formas de dosis cronoterapeuticas.
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
DE102004026706A1 (de) * 2004-05-28 2005-12-15 Merck Patent Gmbh Orale Darreichungsform enthaltend probiotische Bakterien
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
CN100366242C (zh) * 2005-01-13 2008-02-06 杭州容立医药科技有限公司 防滑脱阴道药物释放体系及其制造工艺和在制药中的应用
FR2891459B1 (fr) * 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
SI2049123T2 (sl) 2006-08-03 2016-10-28 Horizon Pharma Ag Zdravljenje revmatoznih bolezni z zadržanim sproščanjem glukokortikoida
US20090028944A1 (en) * 2007-07-16 2009-01-29 Balaji Sathurappan Pharmaceutical compositions comprising mesalamine
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
GB0900350D0 (en) * 2009-01-09 2009-02-11 Cambridge Entpr Ltd Formulations of viable bacteria for oral delivery
CN102784203A (zh) * 2011-05-20 2012-11-21 上海凯宝药业股份有限公司 一种痰热清片剂及其制备方法
JP2014529630A (ja) 2011-09-07 2014-11-13 ザウラー−ブロシュ、ローラント 哺乳類の消化管における一つあるいは複数の物質の放出制御製剤
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
CN102319218B (zh) * 2011-09-22 2014-10-01 贝沃特医药技术(上海)有限公司 一种治疗肠道疾病的药物缓控释微粒制剂及其制备方法
US9763887B2 (en) 2013-03-15 2017-09-19 Allergan Pharmaceuticals International Limited Mesalamine pharmaceutical composition with multiple dosage elements for reduced delivery variability
US10182993B2 (en) 2015-04-06 2019-01-22 Patheon Softgels Inc. Compositions for colonic delivery of drugs
EP3612196A4 (de) 2017-04-18 2021-01-13 Actorius Innovations and Research Pvt. Ltd. Auf polymer basierende formulierung zur freisetzung von wirkstoffen und biowirkstoffen an spezifischen git-stellen
US11524029B2 (en) 2018-08-13 2022-12-13 Viscera Labs, Inc. Therapeutic composition and methods
US11590161B2 (en) 2018-08-13 2023-02-28 Viscera Labs, Inc. Therapeutic composition and methods
EP3662902A1 (de) * 2018-12-07 2020-06-10 Tillotts Pharma AG Formulierung mit freisetzung eines wirkstoffs im kolon
WO2021163007A1 (en) * 2020-02-12 2021-08-19 Viscera Labs, Inc. Therapeutic composition and methods
US11896719B2 (en) * 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
US4668517A (en) * 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
GB8518301D0 (en) * 1985-07-19 1985-08-29 Fujisawa Pharmaceutical Co Hydrodynamically explosive systems
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
IT1260505B (it) * 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon

Also Published As

Publication number Publication date
JP2774080B2 (ja) 1998-07-09
US5482718A (en) 1996-01-09
ATE205705T1 (de) 2001-10-15
PT673645E (pt) 2002-03-28
ZA952169B (en) 1995-09-26
DK0673645T3 (da) 2001-11-12
DE69522729T2 (de) 2002-07-04
CA2142653A1 (en) 1995-09-24
EP0673645B1 (de) 2001-09-19
ES2162874T3 (es) 2002-01-16
CN1112417A (zh) 1995-11-29
NZ270737A (en) 1996-11-26
EP0673645A3 (de) 1996-07-24
RU2138251C1 (ru) 1999-09-27
EP0673645A2 (de) 1995-09-27
AU1488295A (en) 1995-10-05
JPH07277958A (ja) 1995-10-24
PH31334A (en) 1998-07-06
AU696943B2 (en) 1998-09-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee