KR930004304A - 신규한 티아졸릴벤조푸란 유도체, 그의 제조방법 및 이 화합물을 함유하는 약제학적 조성물 - Google Patents

신규한 티아졸릴벤조푸란 유도체, 그의 제조방법 및 이 화합물을 함유하는 약제학적 조성물 Download PDF

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Publication number
KR930004304A
KR930004304A KR1019920014712A KR920014712A KR930004304A KR 930004304 A KR930004304 A KR 930004304A KR 1019920014712 A KR1019920014712 A KR 1019920014712A KR 920014712 A KR920014712 A KR 920014712A KR 930004304 A KR930004304 A KR 930004304A
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KR
South Korea
Prior art keywords
alkyl
compound
formula
salt
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019920014712A
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English (en)
Korean (ko)
Inventor
마사아끼 마쭈오
가쭈오 오꾸무라
신찌 신게나가
히로시 마쭈다
Original Assignee
후지야마 아끼라
후지사와 야꾸힝 고교 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919117733A external-priority patent/GB9117733D0/en
Priority claimed from GB929201057A external-priority patent/GB9201057D0/en
Application filed by 후지야마 아끼라, 후지사와 야꾸힝 고교 가부시끼가이샤 filed Critical 후지야마 아끼라
Publication of KR930004304A publication Critical patent/KR930004304A/ko
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019920014712A 1991-08-16 1992-08-14 신규한 티아졸릴벤조푸란 유도체, 그의 제조방법 및 이 화합물을 함유하는 약제학적 조성물 Ceased KR930004304A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9117733.7 1991-08-16
GB919117733A GB9117733D0 (en) 1991-08-16 1991-08-16 New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same
GB929201057A GB9201057D0 (en) 1992-01-17 1992-01-17 New thiazolylbenzofuran derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB9201057.8 1992-01-17

Publications (1)

Publication Number Publication Date
KR930004304A true KR930004304A (ko) 1993-03-22

Family

ID=26299417

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920014712A Ceased KR930004304A (ko) 1991-08-16 1992-08-14 신규한 티아졸릴벤조푸란 유도체, 그의 제조방법 및 이 화합물을 함유하는 약제학적 조성물

Country Status (16)

Country Link
US (1) US5296495A (enExample)
EP (1) EP0528337B1 (enExample)
JP (1) JP2600644B2 (enExample)
KR (1) KR930004304A (enExample)
CN (1) CN1033088C (enExample)
AT (1) ATE185807T1 (enExample)
AU (1) AU665007B2 (enExample)
CA (1) CA2076192A1 (enExample)
DE (1) DE69230163T2 (enExample)
DK (1) DK0528337T3 (enExample)
ES (1) ES2137169T3 (enExample)
GR (1) GR3032425T3 (enExample)
HU (2) HUT64336A (enExample)
MX (1) MX9204746A (enExample)
SG (1) SG45259A1 (enExample)
TW (1) TW224464B (enExample)

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US7148248B2 (en) 2002-11-29 2006-12-12 Masako Nozaki Method of treating or inhibiting the development of brain inflammation and sepsis
KR20050119201A (ko) * 2003-04-09 2005-12-20 니뽄 다바코 산교 가부시키가이샤 ５원 헤테로방향족 고리 화합물 및 이의 의약적 용도
WO2004106317A1 (ja) 2003-05-29 2004-12-09 The New Industry Research Organization ベンゾフラン化合物、およびそれを含有してなる医薬組成物
JP2005008631A (ja) * 2003-05-29 2005-01-13 New Industry Research Organization ベンゾフラン化合物、およびそれを含有してなる医薬組成物
ITTO20040125A1 (it) * 2004-03-01 2004-06-01 Rotta Research Lab Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica
EP1765333A4 (en) 2004-07-14 2008-06-18 Inflammation Res Ct Company Lt PROCESS FOR INHIBITING TUMOR METASTASES
CA2575932A1 (en) * 2004-08-04 2006-02-16 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
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WO2006046683A1 (en) * 2004-10-25 2006-05-04 Astellas Pharma Inc. Thiazolylbenzofuran derivatives as leukotriene and prostaglandin d2 receptor antagonists
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RU2009104346A (ru) * 2006-07-11 2010-08-20 Шеринг Корпорейшн (US) Ксинафоатная соль замещенного 5-оксазол-2-ил-хинолинового соединения
AU2007319151B2 (en) * 2006-11-16 2013-05-23 Allergan, Inc. Sulfoximines as kinase inhibitors
CA2764830A1 (en) 2009-06-16 2010-12-23 Schering Corporation Novel [3,2-c] heteroaryl steroids as glucocorticoid receptor agonists, compositions and uses thereof
JP2014527511A (ja) 2011-06-24 2014-10-16 アムジエン・インコーポレーテツド Ｔｒｐｍ８拮抗剤及び治療におけるそれらの使用
EP2723718A1 (en) 2011-06-24 2014-04-30 Amgen Inc. Trpm8 antagonists and their use in treatments
WO2013102145A1 (en) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
JP6242810B2 (ja) 2011-12-28 2017-12-06 グローバル・ブラッド・セラピューティクス・インコーポレイテッドＧｌｏｂａｌ Ｂｌｏｏｄ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 置換ベンズアルデヒド化合物および組織酸素化の増加におけるそれらの使用方法
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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SG11201507320QA (en) 2013-03-15 2015-10-29 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
SG11201507453VA (en) 2013-03-15 2015-10-29 Global Blood Therapeutics Inc Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
PL3102208T5 (pl) 2014-02-07 2024-10-14 Global Blood Therapeutics, Inc. Krystaliczny polimorf wolnej zasady 2-hydroksy-6-((2-(1-izopropylo-1h-pirazol-5-ilo)pirydyn-3-ylo)metoksy)benzaldehydu
EA035646B1 (ru) 2014-08-29 2020-07-21 Сиэйчдиай Фаундэйшн, Инк. Зонды для визуализации белка хантингтина
MA41841A (fr) 2015-03-30 2018-02-06 Global Blood Therapeutics Inc Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
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Also Published As

Publication number Publication date
AU2102992A (en) 1993-02-18
TW224464B (enExample) 1994-06-01
DK0528337T3 (da) 2000-03-27
DE69230163T2 (de) 2000-03-23
EP0528337B1 (en) 1999-10-20
JP2600644B2 (ja) 1997-04-16
HU211630A9 (en) 1995-12-28
GR3032425T3 (en) 2000-05-31
CA2076192A1 (en) 1993-02-17
ATE185807T1 (de) 1999-11-15
SG45259A1 (en) 1998-01-16
HUT64336A (en) 1993-12-28
CN1070910A (zh) 1993-04-14
JPH05202040A (ja) 1993-08-10
HU9202656D0 (en) 1992-10-28
DE69230163D1 (de) 1999-11-25
EP0528337A1 (en) 1993-02-24
CN1033088C (zh) 1996-10-23
MX9204746A (es) 1994-04-29
AU665007B2 (en) 1995-12-14
US5296495A (en) 1994-03-22
ES2137169T3 (es) 1999-12-16

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