JP2009504791A5 - - Google Patents

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Publication number
JP2009504791A5
JP2009504791A5 JP2008527370A JP2008527370A JP2009504791A5 JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5 JP 2008527370 A JP2008527370 A JP 2008527370A JP 2008527370 A JP2008527370 A JP 2008527370A JP 2009504791 A5 JP2009504791 A5 JP 2009504791A5
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JP
Japan
Prior art keywords
formula
compound according
methyl
group
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008527370A
Other languages
English (en)
Japanese (ja)
Other versions
JP5237807B2 (ja
JP2009504791A (ja
Filing date
Publication date
Priority claimed from GB0517202A external-priority patent/GB0517202D0/en
Priority claimed from GB0517181A external-priority patent/GB0517181D0/en
Application filed filed Critical
Priority claimed from PCT/EP2006/008200 external-priority patent/WO2007022933A1/en
Publication of JP2009504791A publication Critical patent/JP2009504791A/ja
Publication of JP2009504791A5 publication Critical patent/JP2009504791A5/ja
Application granted granted Critical
Publication of JP5237807B2 publication Critical patent/JP5237807B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2008527370A 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体 Expired - Fee Related JP5237807B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0517202.8 2005-08-22
GB0517202A GB0517202D0 (en) 2005-08-22 2005-08-22 Compounds
GB0517181A GB0517181D0 (en) 2005-08-22 2005-08-22 Compounds
GB0517181.4 2005-08-22
PCT/EP2006/008200 WO2007022933A1 (en) 2005-08-22 2006-08-18 Triazole derivatives as modulators of dopamine d3 receptors

Publications (3)

Publication Number Publication Date
JP2009504791A JP2009504791A (ja) 2009-02-05
JP2009504791A5 true JP2009504791A5 (enExample) 2009-10-01
JP5237807B2 JP5237807B2 (ja) 2013-07-17

Family

ID=37309176

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008527370A Expired - Fee Related JP5237807B2 (ja) 2005-08-22 2006-08-18 ドーパミンｄ３受容体の調節因子としてのトリアゾール誘導体

Country Status (6)

Country Link
US (1) US7799815B2 (enExample)
EP (1) EP1919908B1 (enExample)
JP (1) JP5237807B2 (enExample)
AT (1) ATE487715T1 (enExample)
DE (1) DE602006018152D1 (enExample)
WO (1) WO2007022933A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2557115C (en) * 2004-02-23 2012-10-02 Glaxo Group Limited Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) * 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
JP5068747B2 (ja) * 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
US20070082940A1 (en) 2005-07-27 2007-04-12 Phil Skolnick Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
GB0517187D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517193D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
WO2007113260A1 (en) * 2006-04-03 2007-10-11 Glaxo Group Limited Azabicyclo [3. 1. o] hexyl derivatives as modulators of dopamine d3 receptors
DE602007012531D1 (de) * 2006-04-03 2011-03-31 Glaxo Group Ltd Azabicycloä3.1.0ühexanderivate als modulatoren von dopamin-d3-rezeptoren
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
EP2167083B1 (en) * 2007-06-06 2015-10-28 Euthymics Bioscience, Inc. 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
CN102803224A (zh) 2009-06-26 2012-11-28 万能药生物有限公司 新的氮杂双环己烷类化合物
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters
JP7250405B2 (ja) 2018-01-26 2023-04-03 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する環式化合物
CN113956157B (zh) * 2021-11-18 2024-05-03 西安都创医药科技有限公司 一种合成2-甲酰基-1-环丙烷甲酸乙酯的方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
TWI274750B (en) * 1999-01-12 2007-03-01 Abbott Gmbh & Co Kg Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
DE60305519T2 (de) 2002-10-07 2006-11-23 Glaxo Group Ltd., Greenford Sulfonamidderivate als antipsychotische mittel
DE10304870A1 (de) 2003-02-06 2004-08-19 Abbott Gmbh & Co. Kg Triazolverbindungen und ihre therapeutische Verwendung
CA2557115C (en) 2004-02-23 2012-10-02 Glaxo Group Limited Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine d3 receptors
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507601D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
GB0507680D0 (en) 2005-04-15 2005-05-25 Glaxo Group Ltd Compounds
JP5068747B2 (ja) 2005-06-14 2012-11-07 グラクソ グループ リミテッド ドーパミンｄ３受容体のモジュレーターとしてのアザビシクロ［３．１．０］ヘキサン誘導体
GB0512099D0 (en) * 2005-06-14 2005-07-20 Glaxo Group Ltd Compounds
GB0517193D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Novel use
GB0517191D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517187D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
GB0517175D0 (en) 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
EA200870404A1 (ru) 2006-04-03 2009-04-28 Глэксо Груп Лимитед Производные азабицикло[3.1.0.]гексила в качестве модуляторов рецепторов допамина d3
GB0616574D0 (en) 2006-08-21 2006-09-27 Glaxo Group Ltd Compounds

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