KR920702410A - 수정된 생물학적 물질 - Google Patents

수정된 생물학적 물질

Info

Publication number
KR920702410A
KR920702410A KR1019920700843A KR920700843A KR920702410A KR 920702410 A KR920702410 A KR 920702410A KR 1019920700843 A KR1019920700843 A KR 1019920700843A KR 920700843 A KR920700843 A KR 920700843A KR 920702410 A KR920702410 A KR 920702410A
Authority
KR
South Korea
Prior art keywords
species
receptor
hcrf
animal
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019920700843A
Other languages
English (en)
Korean (ko)
Inventor
제임스 그라함 화이트 데이비드
프레드릭 윌리암스 알란
Original Assignee
원본미기재
임뮤트란 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26296038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR920702410(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB898922987A external-priority patent/GB8922987D0/en
Priority claimed from GB909017198A external-priority patent/GB9017198D0/en
Application filed by 원본미기재, 임뮤트란 리미티드 filed Critical 원본미기재
Publication of KR920702410A publication Critical patent/KR920702410A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/108—Swine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A01K2267/025—Animal producing cells or organs for transplantation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
KR1019920700843A 1989-10-12 1990-10-12 수정된 생물학적 물질 Ceased KR920702410A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB898922987A GB8922987D0 (en) 1989-10-12 1989-10-12 Modified biological material
GB89229878 1989-10-12
GB909017198A GB9017198D0 (en) 1990-08-06 1990-08-06 Modified biological material
GB90171984 1990-08-06
PCT/GB1990/001575 WO1991005855A1 (en) 1989-10-12 1990-10-12 Modified biological material

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019997005897A Division KR100317106B1 (ko) 1989-10-12 1990-10-12 수정된 생물학적 물질

Publications (1)

Publication Number Publication Date
KR920702410A true KR920702410A (ko) 1992-09-04

Family

ID=26296038

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019920700843A Ceased KR920702410A (ko) 1989-10-12 1990-10-12 수정된 생물학적 물질
KR1019997005897A Expired - Fee Related KR100317106B1 (ko) 1989-10-12 1990-10-12 수정된 생물학적 물질

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019997005897A Expired - Fee Related KR100317106B1 (ko) 1989-10-12 1990-10-12 수정된 생물학적 물질

Country Status (27)

Country Link
US (1) US6495735B1 (https=)
EP (2) EP0495852B1 (https=)
JP (1) JP3302358B2 (https=)
KR (2) KR920702410A (https=)
CN (2) CN1122719C (https=)
AT (1) ATE139562T1 (https=)
AU (1) AU654116B2 (https=)
BG (1) BG61080B1 (https=)
CA (1) CA2067235A1 (https=)
CY (1) CY1996A (https=)
DE (2) DE495852T1 (https=)
DK (1) DK0495852T3 (https=)
ES (1) ES2060561T3 (https=)
FI (1) FI921618A7 (https=)
GR (2) GR940300004T1 (https=)
HK (1) HK48497A (https=)
HU (1) HUT64584A (https=)
IE (1) IE75345B1 (https=)
IL (2) IL95970A0 (https=)
IN (1) IN171948B (https=)
MY (1) MY107433A (https=)
NO (2) NO303502B1 (https=)
NZ (2) NZ235657A (https=)
PT (2) PT95580B (https=)
RO (1) RO109863B1 (https=)
SG (1) SG72614A1 (https=)
WO (1) WO1991005855A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705732A (en) * 1989-06-12 1998-01-06 Oklahoma Medical Research Foundation Universal donor cells
AU651068B2 (en) * 1989-07-21 1994-07-14 Washington University Recombinantly produced human membrane cofactor protein (MCP)
US5846715A (en) * 1990-05-11 1998-12-08 The Austin Research Institute CD46 variants
CA2082277A1 (en) * 1990-05-11 1991-11-12 Damien F. J. Purcell Cd46 variants
EP1041142A3 (en) * 1991-07-15 2007-10-24 Oklahoma Medical Research Foundation Universal donor cells
US6916654B1 (en) * 1992-06-29 2005-07-12 Oklahoma Medical Research Foundation Universal donor cells
FI951325L (fi) * 1992-09-22 1995-05-09 Dnx Biotherapeutics Inc Proteiinien kuljetus membraanien välisellä siirrolla ksenogeenisten elinsiirrännäisten esisovittamista varten ja muihin tarkoituksiin
US5627264A (en) * 1994-03-03 1997-05-06 Alexion Pharmaceuticals, Inc. Chimeric complement inhibitor proteins
CA2196311A1 (en) * 1994-08-19 1996-02-29 David H. Sachs Genetically engineered swine cells
CA2227584A1 (en) * 1995-08-04 1997-02-20 The General Hospital Corporation Transgenic swine and swine cells having human hla genes
US6166288A (en) * 1995-09-27 2000-12-26 Nextran Inc. Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
AU1933897A (en) * 1996-03-22 1997-10-17 Imutran Limited Surfaces which prevent or reduce complement activation
DE69833545T2 (de) 1997-03-26 2006-12-14 Imperial College Innovations Ltd. In der zellmembran verankertes antikoagulant-fusionsprotein
AU7935598A (en) 1997-07-14 1999-02-10 Nippon Meat Packers, Inc. Transgenic mammals
US7419683B2 (en) * 1997-10-31 2008-09-02 United States Of America As Represented By The Secretary Of The Army Method of inhibiting side effects of pharmaceutical compositions containing amphiphilic vehicles or drug carrier molecules
SE523817C2 (sv) * 1999-02-05 2004-05-18 Corline Systems Ab Användning av ett koagulationsförebyggande ämne i samband med transplantation av insulinproducerande celler
GB9905503D0 (en) 1999-03-10 1999-05-05 Adprotech Plc Novel compound formulations and methods of delivery
WO2005009134A1 (en) 2003-07-21 2005-02-03 Lifecell Corporation ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE
CA3104704A1 (en) 2009-08-14 2011-02-17 Revivicor, Inc. Multi-transgenic pigs for diabetes treatment
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
CA2810016A1 (en) 2010-09-03 2012-03-08 Stem Centrx, Inc. Novel modulators and methods of use
CN103492576A (zh) 2011-02-14 2014-01-01 雷维维科公司 用于血管化异种移植物及其衍生物的异种移植的遗传修饰的猪
EP3065790B1 (en) 2013-11-04 2020-10-28 LifeCell Corporation Methods of removing alpha-galactose
CN114686427B (zh) * 2022-05-23 2022-07-29 中国人民解放军总医院第一医学中心 一种脾脏调节型b淋巴细胞及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081570A4 (en) * 1981-06-12 1985-09-02 Univ Ohio GENETIC TRANSFORMATION OF ZYGOTS.
US4431636A (en) 1982-05-24 1984-02-14 American Cyanamid Company Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US5109113A (en) * 1986-05-02 1992-04-28 Genentech, Inc. Membrane anchor fusion polypeptides
JPS62104594A (ja) * 1985-10-31 1987-05-15 Terumo Corp クエン酸塩利用能検査用培地組成物
JPH0742235B2 (ja) * 1985-11-08 1995-05-10 三共株式会社 自己免疫性疾病の予防・治療剤
IL82390A0 (en) * 1986-05-02 1987-10-30 Genentech Inc Nucleic acid and methods for the synthesis of novel daf compositions
GB8615942D0 (en) * 1986-06-30 1986-08-06 Animal & Food Research Council Peptide production
IL89790A (en) * 1988-04-01 2002-05-23 Johns Hopking University Nucleic acid sequences that encode and cells that produce cr1 protein and methods of production and purification
DE3830271A1 (de) 1988-09-06 1990-03-15 Goetze Otto Mittel mit immunsuppressiver wirkung
US5573940A (en) * 1989-06-12 1996-11-12 Oklahoma Medical Research Foundation Cells expressing high levels of CD59

Also Published As

Publication number Publication date
DE69027535T2 (de) 1996-11-28
EP0495852A1 (en) 1992-07-29
NO982131L (no) 1992-04-10
EP0709459A3 (en) 1999-01-07
JPH05503074A (ja) 1993-05-27
AU654116B2 (en) 1994-10-27
ES2060561T1 (es) 1994-12-01
DE495852T1 (de) 1994-03-31
CN1051199A (zh) 1991-05-08
BG61080B1 (bg) 1996-10-31
FI921618A0 (fi) 1992-04-10
US6495735B1 (en) 2002-12-17
NO982131D0 (no) 1998-05-11
NO921438D0 (no) 1992-04-10
EP0495852B1 (en) 1996-06-19
ATE139562T1 (de) 1996-07-15
DE69027535D1 (de) 1996-07-25
HK48497A (en) 1997-04-25
EP0709459A2 (en) 1996-05-01
PT101896B (pt) 2003-01-31
CY1996A (en) 1997-09-05
IL120795A0 (en) 1997-09-30
AU6539290A (en) 1991-05-16
NZ235657A (en) 1994-05-26
GR3020741T3 (en) 1996-11-30
SG72614A1 (en) 2000-05-23
WO1991005855A1 (en) 1991-05-02
HUT64584A (en) 1994-01-28
HU9201240D0 (en) 1992-06-29
NO303502B1 (no) 1998-07-20
IE903649A1 (en) 1991-04-24
PT95580A (pt) 1991-09-13
IE75345B1 (en) 1997-08-27
CN1122719C (zh) 2003-10-01
IL95970A0 (en) 1992-05-25
MY107433A (en) 1995-12-30
IN171948B (https=) 1993-02-13
ES2060561T3 (es) 1996-08-01
JP3302358B2 (ja) 2002-07-15
CA2067235A1 (en) 1991-04-13
CN1491624A (zh) 2004-04-28
NZ248153A (en) 1997-07-27
FI921618L (fi) 1992-04-10
RO109863B1 (ro) 1995-06-30
DK0495852T3 (da) 1996-07-15
NO921438L (no) 1992-04-10
PT101896A (pt) 1998-02-27
BG96329A (bg) 1993-12-24
PT95580B (pt) 1999-05-31
GR940300004T1 (en) 1994-02-28
FI921618A7 (fi) 1992-04-10
KR100317106B1 (ko) 2001-12-22

Similar Documents

Publication Publication Date Title
KR920702410A (ko) 수정된 생물학적 물질
Ponder et al. Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation.
Verri et al. Molecular and functional characterisation of the zebrafish (Danio rerio) PEPT1‐type peptide transporter 1
Linhart et al. C/EBPα is required for differentiation of white, but not brown, adipose tissue
Rosen et al. Regulation of milk protein gene expression
Niemann et al. Cytomegalovirus early promoter induced expression of hcd59 in porcine organs provides protection against hyperacute rejection1
Russell et al. Long-continued function of normal blood-forming tissue transplanted into genetically anemic hosts
Farlora et al. Intraperitoneal germ cell transplantation in the Nile tilapia Oreochromis niloticus
Mueller et al. Immediate and persistent effects of temperature on oxygen consumption and thermal tolerance in embryos and larvae of the Baja California chorus frog, Pseudacris hypochondriaca
Wang et al. Transgenic expression of human cytoxic T-lymphocyte associated antigen4-immunoglobulin (hCTLA4Ig) by porcine skin for xenogeneic skin grafting
Kano et al. Xenotransplantation and interspecies organogenesis: current status and issues
Chen et al. Elimination of donor CD47 protects against vascularized allograft rejection in mice
Yannoutsos et al. A membrane cofactor protein transgenic mouse model for the study of discordant xenograft rejection
US12207629B2 (en) Identification of porcine xenoantigens
Ma et al. Expression of the Ly‐6A (Sca‐1) lacZ transgene in mouse haematopoietic stem cells and embryos
White et al. The control of hyperacute rejection by genetic engineering of the donor species
Sandstrom The growth and differentiation of duck kidney tissue on the chorio-allantoic membrane of the chick and duck
AU7935598A (en) Transgenic mammals
Reshkin et al. Preservation of glucose transport and enzyme activity in fish intestinal brush-border and basolateral membrane vesicles
RU2195956C2 (ru) Способ трансплантации животной клетки, ткани или органа реципиенту и средство для его осуществления
Gong et al. Comparison of primordial germ cell differences at different developmental time points in chickens
Nakahara et al. Generation of a T lx1 C re ER‐V enus knock‐in mouse strain for the study of spleen development
WANG et al. Presence of Human Chromosome 1 with Expression of Human Decay‐Accelerating Factor (DAF) Prevents Lysis of Mouse/Human Hybrid Cells by Human Complement
Voskoboynik et al. Stem cells, chimerism and tolerance: Lessons from mammals and ascidians
Even et al. After migration into blood circulation, hematopoietic stem cells can stably self-renew and maintain bone marrow while being skewed toward myeloid lineage when submitted to serial transplantation

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19920411

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19950913

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19920411

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19980721

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19990226

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19980721

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 19990528

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 19990226

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20000531

Appeal identifier: 1999101001884

Request date: 19990528

A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 19990628

PB0901 Examination by re-examination before a trial

Comment text: Request for Trial against Decision on Refusal

Patent event date: 19990528

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 19981224

Patent event code: PB09011R02I

B601 Maintenance of original decision after re-examination before a trial
PB0601 Maintenance of original decision after re-examination before a trial
J301 Trial decision

Free format text: TRIAL DECISION FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 19990528

Effective date: 20000531

PJ1301 Trial decision

Patent event code: PJ13011S01D

Patent event date: 20000617

Comment text: Trial Decision on Objection to Decision on Refusal

Appeal kind category: Appeal against decision to decline refusal

Request date: 19990528

Decision date: 20000531

Appeal identifier: 1999101001884

J2X1 Appeal (before the patent court)

Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL

PJ2001 Appeal

Patent event date: 20000617

Comment text: Trial Decision on Objection to Decision on Refusal

Patent event code: PJ20011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20010726

Appeal identifier: 2000201004640

Request date: 20000720

J302 Written judgement (patent court)

Free format text: JUDGMENT (PATENT COURT) FOR APPEAL AGAINST DECISION TO DECLINE REFUSAL REQUESTED 20000720

Effective date: 20010726

PJ1302 Judgment (patent court)

Patent event date: 20010731

Comment text: Written Judgment (Patent Court)

Patent event code: PJ13021S01D

Request date: 20000720

Decision date: 20010726

Appeal identifier: 2000201004640

Appeal kind category: Appeal against decision to decline refusal

PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20010808

WITB Written withdrawal of application