KR900002801A - 당뇨병 치료용 약학적제제 - Google Patents

당뇨병 치료용 약학적제제 Download PDF

Info

Publication number
KR900002801A
KR900002801A KR1019890011430A KR890011430A KR900002801A KR 900002801 A KR900002801 A KR 900002801A KR 1019890011430 A KR1019890011430 A KR 1019890011430A KR 890011430 A KR890011430 A KR 890011430A KR 900002801 A KR900002801 A KR 900002801A
Authority
KR
South Korea
Prior art keywords
insulin
formula
arg
pharmaceutical formulation
formulation according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019890011430A
Other languages
English (en)
Korean (ko)
Inventor
되르슈크 미카엘
Original Assignee
하인리히 벡커, 베른하르트 벡크
훽스트 아크티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 하인리히 벡커, 베른하르트 벡크, 훽스트 아크티엔게젤샤프트 filed Critical 하인리히 벡커, 베른하르트 벡크
Publication of KR900002801A publication Critical patent/KR900002801A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019890011430A 1988-08-13 1989-08-11 당뇨병 치료용 약학적제제 Withdrawn KR900002801A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3827533A DE3827533A1 (de) 1988-08-13 1988-08-13 Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DEP3827533.3 1988-08-13

Publications (1)

Publication Number Publication Date
KR900002801A true KR900002801A (ko) 1990-03-23

Family

ID=6360797

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890011430A Withdrawn KR900002801A (ko) 1988-08-13 1989-08-11 당뇨병 치료용 약학적제제

Country Status (18)

Country Link
US (1) US5177058A (cg-RX-API-DMAC10.html)
EP (1) EP0357978B1 (cg-RX-API-DMAC10.html)
JP (1) JPH02101022A (cg-RX-API-DMAC10.html)
KR (1) KR900002801A (cg-RX-API-DMAC10.html)
AT (1) ATE75945T1 (cg-RX-API-DMAC10.html)
AU (1) AU621648B2 (cg-RX-API-DMAC10.html)
CA (1) CA1332354C (cg-RX-API-DMAC10.html)
DE (2) DE3827533A1 (cg-RX-API-DMAC10.html)
DK (1) DK395689A (cg-RX-API-DMAC10.html)
ES (1) ES2039773T3 (cg-RX-API-DMAC10.html)
FI (1) FI95202C (cg-RX-API-DMAC10.html)
GR (1) GR3005326T3 (cg-RX-API-DMAC10.html)
HU (1) HU203670B (cg-RX-API-DMAC10.html)
IE (1) IE61266B1 (cg-RX-API-DMAC10.html)
NO (1) NO178914C (cg-RX-API-DMAC10.html)
NZ (1) NZ230280A (cg-RX-API-DMAC10.html)
PT (1) PT91420B (cg-RX-API-DMAC10.html)
ZA (1) ZA896149B (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100547922B1 (ko) * 1996-07-26 2006-06-22 훽스트 악티엔게젤샤프트 아연결합이증가된인슐린유도체및이를함유하는약제학적제제

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6875589B1 (en) * 1988-06-23 2005-04-05 Hoechst Aktiengesellschaft Mini-proinsulin, its preparation and use
DE4024434A1 (de) * 1990-08-01 1992-02-13 Fresenius Ag Vorrichtung zur ultrafiltrationskontrolle bzw. ultrafiltrationsregelung bei blutreinigungsverfahren
NZ250844A (en) * 1993-04-07 1996-03-26 Pfizer Treatment of non-insulin dependant diabetes with peptides; composition
US5534488A (en) * 1993-08-13 1996-07-09 Eli Lilly And Company Insulin formulation
AR002976A1 (es) * 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
EP1044016B1 (en) * 1998-01-09 2005-03-16 Novo Nordisk A/S Stabilised insulin compositions
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE10114178A1 (de) * 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
CZ2004710A3 (cs) * 2001-12-20 2005-02-16 Eli Lilly And Company Inzulínová sloučenina s protrahovaným účinkem
DE10227232A1 (de) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
WO2004096854A2 (en) * 2003-04-29 2004-11-11 Eli Lilly And Company Insulin analogs having protracted time action
EP2264065B1 (en) * 2003-08-05 2017-03-08 Novo Nordisk A/S Novel insulin derivatives
CN101027318B (zh) * 2004-07-19 2016-05-25 比奥孔有限公司 胰岛素-低聚物共轭物，制剂及其用途
PL1969004T3 (pl) * 2005-12-28 2012-01-31 Novo Nordisk As Kompozycje zawierające acylowaną insulinę i cynk oraz sposób wytwarzania tych kompozycji
ES2744384T3 (es) * 2007-06-13 2020-02-24 Novo Nordisk As Formulación farmacéutica que comprende un derivado de insulina
JP5868594B2 (ja) * 2007-10-16 2016-02-24 バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ 経口投与可能な固形医薬組成物及びそのプロセス
CN103736082A (zh) 2008-10-17 2014-04-23 赛诺菲-安万特德国有限公司 胰岛素和glp-1激动剂的组合
MX2011004357A (es) * 2008-10-30 2011-05-23 Novo Nordisk As Tratamiento de diabetes mellitus utilizando inyecciones de insulina con una frecuencia de inyeccion menor que a diario.
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
CN102711804B (zh) 2009-11-13 2015-09-16 赛诺菲-安万特德国有限公司 包含glp-1激动剂和甲硫氨酸的药物组合物
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
JP6049625B2 (ja) 2010-10-27 2016-12-21 ノヴォ ノルディスク アー／エス 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
ES2550357T3 (es) 2011-08-29 2015-11-06 Sanofi-Aventis Deutschland Gmbh Combinación farmacéutica para su uso en el control glucémico en pacientes de diabetes de tipo 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
EP2991672A1 (en) 2013-04-30 2016-03-09 Novo Nordisk A/S Novel administration regime
KR102578030B1 (ko) 2014-12-12 2023-09-14 사노피-아벤티스 도이칠란트 게엠베하 인슐린 글라진／릭시세나티드 고정비 제형
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
JP7518149B2 (ja) 2019-07-12 2024-07-17 ノヴォ ノルディスク アー／エス 高濃度インスリン製剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2143591A (en) * 1936-09-26 1939-01-10 Univ Alberta Therapeutic preparation and process of making and using it
US2354211A (en) * 1940-07-02 1944-07-25 Burroughs Wellcome Co Insulin preparation
DOP1982004086A (es) * 1981-08-27 1988-03-22 Lilly Co Eli Formula farmaceutica que comprende insulina humana y proinsulina humana
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DE3334407A1 (de) * 1983-09-23 1985-04-04 Hoechst Ag, 6230 Frankfurt In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100547922B1 (ko) * 1996-07-26 2006-06-22 훽스트 악티엔게젤샤프트 아연결합이증가된인슐린유도체및이를함유하는약제학적제제

Also Published As

Publication number Publication date
PT91420B (pt) 1995-05-04
NO178914B (no) 1996-03-25
DK395689D0 (da) 1989-08-11
DK395689A (da) 1990-02-14
PT91420A (pt) 1990-03-08
DE58901401D1 (de) 1992-06-17
HUT50443A (en) 1990-02-28
ES2039773T3 (es) 1996-07-16
AU3951489A (en) 1990-02-15
NO893239L (no) 1990-02-14
US5177058A (en) 1993-01-05
EP0357978B1 (de) 1992-05-13
FI95202B (fi) 1995-09-29
FI893783L (fi) 1990-02-14
FI95202C (fi) 1996-01-10
JPH02101022A (ja) 1990-04-12
EP0357978A1 (de) 1990-03-14
CA1332354C (en) 1994-10-11
NO178914C (no) 1996-07-03
GR3005326T3 (cg-RX-API-DMAC10.html) 1993-05-24
IE61266B1 (en) 1994-10-19
FI893783A0 (fi) 1989-08-10
ZA896149B (en) 1990-04-25
NO893239D0 (no) 1989-08-11
DE3827533A1 (de) 1990-02-15
IE892594L (en) 1990-02-13
ATE75945T1 (de) 1992-05-15
NZ230280A (en) 1991-09-25
AU621648B2 (en) 1992-03-19
HU203670B (en) 1991-09-30

Similar Documents

Publication Publication Date Title
KR900002801A (ko) 당뇨병 치료용 약학적제제
KR900009698A (ko) 인슐린 유도체, 이의 제조방법, 이의 용도 및 이를 함유하는 약제학적 제제
KR900007435A (ko) 인슐린 유도체, 이의 용도, 및 이를 함유하는 약제학적 조성물
EP0105759B1 (en) Human pancreatic grf
US4415558A (en) CRF And analogs
KR880001701A (ko) 신규한 펩티드
WO1997040070A1 (en) Conjugates of lipophilic moieties and fragments of vasoactive intestinal peptide (vip)
KR950701937A (ko) 글루카곤-유사 펩티드 및 인슐리노트로핀 유도체(glucagon-like peptide and insulinotropin derivatives)
EP0117034B1 (en) Grf analogs
DE68914205T2 (de) Zyklische GRF-Analoge.
KR900003205A (ko) 제약 화합물
KR910009930A (ko) 인슐린 유도체, 이의 제조방법, 이의 용도 및 이를 함유하는 약제
US4623716A (en) Process for the preparation and purification of peptides
KR927002373A (ko) 성장 호르몬 분비 활성을 갖는 폴리펩타이드 화합물
US5079231A (en) Immunostimulating peptides, a process for their preparation and pharmaceutical compositions containing them
US3849388A (en) Analogues of human thyrocalcitonin
EP0067608A1 (en) CRF and analogs
KR920701244A (ko) 심실 펩티드 유도체
US4552764A (en) Peptides for control of intestinal motility
KR900701298A (ko) T-세포 억제작용을 보유한 펩티드
US3991041A (en) (Phe3 -Ala)1 -somatostatin
JPS636560B2 (cg-RX-API-DMAC10.html)
KR850000980A (ko) 인슐린 유도체의 제조방법
KR890002232A (ko) 펩타이드 및 그의 제조방법

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19890811

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid