KR890011884A - 캠프토데신 유도체 - Google Patents

캠프토데신 유도체 Download PDF

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Publication number
KR890011884A
KR890011884A KR1019890000524A KR890000524A KR890011884A KR 890011884 A KR890011884 A KR 890011884A KR 1019890000524 A KR1019890000524 A KR 1019890000524A KR 890000524 A KR890000524 A KR 890000524A KR 890011884 A KR890011884 A KR 890011884A
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KR
South Korea
Prior art keywords
group
hydroxyl
amino
hydrogen
lower alkyl
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Application number
KR1019890000524A
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English (en)
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KR960007866B1 (ko
Inventor
다까시 야에가시
사토루 오까지마
세이고 사와다
겐이치로오 노가라
겐이치 데즈까
히로시 나가타
데루오 요코쿠라
타다시 미야사까
Original Assignee
구와하라 쥰
가부시끼 가이샤 야쿠루토 혼샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 구와하라 쥰, 가부시끼 가이샤 야쿠루토 혼샤 filed Critical 구와하라 쥰
Publication of KR890011884A publication Critical patent/KR890011884A/ko
Application granted granted Critical
Publication of KR960007866B1 publication Critical patent/KR960007866B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

캠프토데신 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 일반식(Ⅰ)
    (식중에서 R1은 저급알킬기를 나타내고, R2는 수소원자, 아미노기, 수산기, 저급아실아미노기 또는 저급 알콕실기를 나타내며, R3은, 수소원자, 할로겐원자, 저급알킬기, 수산기 저급알콕실기, 니트로기, 아미노기, 시아노기 또는디 저급알킬아미노기를 나타내고, R4는 수소원자, 할로겐원자, 저급알킬기, 수산기, 저급알콕실기, 저급알킬티오기, 아미노기, 시아노기, 또는 디 저급알킬아미노기를 나타내며, R5는, 수소원자, 할로겐원자, 수산기, 또는 저급 알콕실기를 나타냄. 다만, R2, R3, R4및 R5가 동시에 수소원자인 경우는 없고, 또한, R2, R3, R4및 R5중의 어느 하나가 수산기 또는 저급 알콕실기인 경우에는 나머지 전부가 동시에 수소원자인 경우도 없다)로 나타내어지는 캠프토데신 유도체.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890000524A 1988-01-20 1989-01-19 캠프토데신 유도체 KR960007866B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63008388A JPH0615547B2 (ja) 1988-01-20 1988-01-20 新規なカンプトテシン誘導体
JP8388 1988-01-20

Publications (2)

Publication Number Publication Date
KR890011884A true KR890011884A (ko) 1989-08-23
KR960007866B1 KR960007866B1 (ko) 1996-06-13

Family

ID=11691823

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890000524A KR960007866B1 (ko) 1988-01-20 1989-01-19 캠프토데신 유도체

Country Status (9)

Country Link
US (1) US5061800A (ko)
EP (1) EP0325247B1 (ko)
JP (1) JPH0615547B2 (ko)
KR (1) KR960007866B1 (ko)
AT (1) ATE89559T1 (ko)
CA (1) CA1332414C (ko)
DE (1) DE68906552T2 (ko)
ES (1) ES2056962T3 (ko)
GR (1) GR3007919T3 (ko)

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Also Published As

Publication number Publication date
DE68906552T2 (de) 1993-12-16
US5061800A (en) 1991-10-29
EP0325247A1 (en) 1989-07-26
EP0325247B1 (en) 1993-05-19
DE68906552D1 (de) 1993-06-24
JPH0615547B2 (ja) 1994-03-02
GR3007919T3 (ko) 1993-08-31
KR960007866B1 (ko) 1996-06-13
JPH01186892A (ja) 1989-07-26
CA1332414C (en) 1994-10-11
ES2056962T3 (es) 1994-10-16
ATE89559T1 (de) 1993-06-15

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