KR880003956A - 신규 세팔로스포린 화합물 - Google Patents
신규 세팔로스포린 화합물 Download PDFInfo
- Publication number
- KR880003956A KR880003956A KR870010622A KR870010622A KR880003956A KR 880003956 A KR880003956 A KR 880003956A KR 870010622 A KR870010622 A KR 870010622A KR 870010622 A KR870010622 A KR 870010622A KR 880003956 A KR880003956 A KR 880003956A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- group
- salts
- formula
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- -1 Cephalosporin Compounds Chemical class 0.000 title claims 7
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 16
- 150000003839 salts Chemical class 0.000 claims 11
- 239000012453 solvate Substances 0.000 claims 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 5
- 230000036571 hydration Effects 0.000 claims 4
- 238000006703 hydration reaction Methods 0.000 claims 4
- 231100000252 nontoxic Toxicity 0.000 claims 4
- 230000003000 nontoxic effect Effects 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 150000002148 esters Chemical class 0.000 claims 3
- 150000004677 hydrates Chemical class 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 125000003368 amide group Chemical group 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000002441 X-ray diffraction Methods 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 claims 1
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 150000002009 diols Chemical group 0.000 claims 1
- 238000006266 etherification reaction Methods 0.000 claims 1
- 238000002329 infrared spectrum Methods 0.000 claims 1
- 150000002923 oximes Chemical class 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8623212 | 1986-09-26 | ||
| GB868623212A GB8623212D0 (en) | 1986-09-26 | 1986-09-26 | Chemical compounds |
| GB878705986A GB8705986D0 (en) | 1987-03-13 | 1987-03-13 | Chemical compounds |
| GB8705986 | 1987-03-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR880003956A true KR880003956A (ko) | 1988-05-31 |
Family
ID=26291340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR870010622A Withdrawn KR880003956A (ko) | 1986-09-26 | 1987-09-25 | 신규 세팔로스포린 화합물 |
Country Status (21)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0400805A1 (en) * | 1989-04-25 | 1990-12-05 | Toshiyasu Ishimaru | Cephalosporin compounds and their use |
| KR970005896B1 (ko) * | 1993-07-23 | 1997-04-21 | 주식회사 엘지화학 | 신규 세팔로스포린계 항생제 및 그의 제조방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| JPS6011917B2 (ja) * | 1981-04-09 | 1985-03-28 | 山之内製薬株式会社 | 新規なセファロスポリン化合物 |
| JPS62167784A (ja) * | 1985-07-27 | 1987-07-24 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
| AU586229B2 (en) * | 1985-04-01 | 1989-07-06 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
-
1987
- 1987-09-23 IL IL83993A patent/IL83993A0/xx unknown
- 1987-09-25 BE BE8701088A patent/BE1002248A5/fr not_active IP Right Cessation
- 1987-09-25 CH CH3723/87A patent/CH676850A5/de not_active IP Right Cessation
- 1987-09-25 GR GR871487A patent/GR871487B/el unknown
- 1987-09-25 ES ES8702747A patent/ES2008739A6/es not_active Expired
- 1987-09-25 IT IT48421/87A patent/IT1221510B/it active
- 1987-09-25 NL NL8702295A patent/NL8702295A/nl not_active Application Discontinuation
- 1987-09-25 DE DE19873732457 patent/DE3732457A1/de not_active Withdrawn
- 1987-09-25 SE SE8703701A patent/SE8703701L/ not_active Application Discontinuation
- 1987-09-25 KR KR870010622A patent/KR880003956A/ko not_active Withdrawn
- 1987-09-25 GB GB8722574A patent/GB2197649B/en not_active Expired - Fee Related
- 1987-09-25 FR FR8713324A patent/FR2604437A1/fr active Pending
- 1987-09-25 FI FI874211A patent/FI874211A7/fi not_active Application Discontinuation
- 1987-09-25 PH PH8735853A patent/PH25299A/en unknown
- 1987-09-25 NO NO874044A patent/NO874044L/no unknown
- 1987-09-25 AT AT872440A patent/ATA244087A/de not_active Application Discontinuation
- 1987-09-25 PT PT85792A patent/PT85792B/pt not_active IP Right Cessation
- 1987-09-25 AU AU78960/87A patent/AU607937B2/en not_active Withdrawn - After Issue
- 1987-09-25 DK DK503787A patent/DK503787A/da not_active Application Discontinuation
- 1987-09-25 LU LU87002A patent/LU87002A1/fr unknown
- 1987-09-25 HU HU874312A patent/HU201946B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT85792B (pt) | 1990-08-31 |
| BE1002248A5 (fr) | 1990-11-06 |
| NO874044D0 (no) | 1987-09-25 |
| CH676850A5 (enrdf_load_stackoverflow) | 1991-03-15 |
| SE8703701L (sv) | 1988-03-27 |
| PH25299A (en) | 1991-04-30 |
| AU607937B2 (en) | 1991-03-21 |
| DE3732457A1 (de) | 1988-03-31 |
| IT8748421A0 (it) | 1987-09-25 |
| DK503787A (da) | 1988-03-27 |
| FI874211A0 (fi) | 1987-09-25 |
| IT1221510B (it) | 1990-07-06 |
| HU201946B (en) | 1991-01-28 |
| NO874044L (no) | 1988-03-28 |
| AU7896087A (en) | 1988-03-31 |
| FI874211A7 (fi) | 1988-03-27 |
| ATA244087A (de) | 1991-02-15 |
| FR2604437A1 (fr) | 1988-04-01 |
| DK503787D0 (da) | 1987-09-25 |
| GB2197649A (en) | 1988-05-25 |
| GR871487B (en) | 1988-02-04 |
| IL83993A0 (en) | 1988-02-29 |
| GB8722574D0 (en) | 1987-11-04 |
| SE8703701D0 (sv) | 1987-09-25 |
| ES2008739A6 (es) | 1989-08-01 |
| NL8702295A (nl) | 1988-04-18 |
| HUT45539A (en) | 1988-07-28 |
| GB2197649B (en) | 1990-03-28 |
| PT85792A (en) | 1987-10-01 |
| LU87002A1 (fr) | 1988-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19870925 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |