PT85792B - Processo para a preparacao de compostos de cefalosporina e seus derivados e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de compostos de cefalosporina e seus derivados e de composicoes farmaceuticas que os contem Download PDFInfo
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- PT85792B PT85792B PT85792A PT8579287A PT85792B PT 85792 B PT85792 B PT 85792B PT 85792 A PT85792 A PT 85792A PT 8579287 A PT8579287 A PT 8579287A PT 85792 B PT85792 B PT 85792B
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- 229920001447 polyvinyl benzene Polymers 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- LPNYRYFBWFDTMA-UHFFFAOYSA-N potassium tert-butoxide Chemical compound [K+].CC(C)(C)[O-] LPNYRYFBWFDTMA-UHFFFAOYSA-N 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 230000001012 protector Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000005588 protonation Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
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- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 description 1
- JVBXVOWTABLYPX-UHFFFAOYSA-L sodium dithionite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])=O JVBXVOWTABLYPX-UHFFFAOYSA-L 0.000 description 1
- 239000012312 sodium hydride Substances 0.000 description 1
- 229910000104 sodium hydride Inorganic materials 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 238000003797 solvolysis reaction Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
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- 239000000375 suspending agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
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- ISIJQEHRDSCQIU-UHFFFAOYSA-N tert-butyl 2,7-diazaspiro[4.5]decane-7-carboxylate Chemical compound C1N(C(=O)OC(C)(C)C)CCCC11CNCC1 ISIJQEHRDSCQIU-UHFFFAOYSA-N 0.000 description 1
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- 229940124597 therapeutic agent Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868623212A GB8623212D0 (en) | 1986-09-26 | 1986-09-26 | Chemical compounds |
| GB878705986A GB8705986D0 (en) | 1987-03-13 | 1987-03-13 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT85792A PT85792A (en) | 1987-10-01 |
| PT85792B true PT85792B (pt) | 1990-08-31 |
Family
ID=26291340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT85792A PT85792B (pt) | 1986-09-26 | 1987-09-25 | Processo para a preparacao de compostos de cefalosporina e seus derivados e de composicoes farmaceuticas que os contem |
Country Status (21)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0400805A1 (en) * | 1989-04-25 | 1990-12-05 | Toshiyasu Ishimaru | Cephalosporin compounds and their use |
| KR970005896B1 (ko) * | 1993-07-23 | 1997-04-21 | 주식회사 엘지화학 | 신규 세팔로스포린계 항생제 및 그의 제조방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| JPS6011917B2 (ja) * | 1981-04-09 | 1985-03-28 | 山之内製薬株式会社 | 新規なセファロスポリン化合物 |
| AU586229B2 (en) * | 1985-04-01 | 1989-07-06 | Mochida Pharmaceutical Co., Ltd. | Cephalosporin derivatives |
| JPS62167784A (ja) * | 1985-07-27 | 1987-07-24 | Mochida Pharmaceut Co Ltd | 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤 |
-
1987
- 1987-09-23 IL IL83993A patent/IL83993A0/xx unknown
- 1987-09-25 GR GR871487A patent/GR871487B/el unknown
- 1987-09-25 KR KR870010622A patent/KR880003956A/ko not_active Withdrawn
- 1987-09-25 ES ES8702747A patent/ES2008739A6/es not_active Expired
- 1987-09-25 HU HU874312A patent/HU201946B/hu not_active IP Right Cessation
- 1987-09-25 DK DK503787A patent/DK503787A/da not_active Application Discontinuation
- 1987-09-25 FI FI874211A patent/FI874211A7/fi not_active Application Discontinuation
- 1987-09-25 LU LU87002A patent/LU87002A1/fr unknown
- 1987-09-25 PH PH8735853A patent/PH25299A/en unknown
- 1987-09-25 GB GB8722574A patent/GB2197649B/en not_active Expired - Fee Related
- 1987-09-25 DE DE19873732457 patent/DE3732457A1/de not_active Withdrawn
- 1987-09-25 SE SE8703701A patent/SE8703701L/ not_active Application Discontinuation
- 1987-09-25 NO NO874044A patent/NO874044L/no unknown
- 1987-09-25 CH CH3723/87A patent/CH676850A5/de not_active IP Right Cessation
- 1987-09-25 PT PT85792A patent/PT85792B/pt not_active IP Right Cessation
- 1987-09-25 AU AU78960/87A patent/AU607937B2/en not_active Withdrawn - After Issue
- 1987-09-25 NL NL8702295A patent/NL8702295A/nl not_active Application Discontinuation
- 1987-09-25 IT IT48421/87A patent/IT1221510B/it active
- 1987-09-25 BE BE8701088A patent/BE1002248A5/fr not_active IP Right Cessation
- 1987-09-25 AT AT872440A patent/ATA244087A/de not_active Application Discontinuation
- 1987-09-25 FR FR8713324A patent/FR2604437A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUT45539A (en) | 1988-07-28 |
| NO874044D0 (no) | 1987-09-25 |
| KR880003956A (ko) | 1988-05-31 |
| SE8703701D0 (sv) | 1987-09-25 |
| GB2197649A (en) | 1988-05-25 |
| IL83993A0 (en) | 1988-02-29 |
| AU7896087A (en) | 1988-03-31 |
| LU87002A1 (fr) | 1988-03-02 |
| PH25299A (en) | 1991-04-30 |
| GB8722574D0 (en) | 1987-11-04 |
| PT85792A (en) | 1987-10-01 |
| CH676850A5 (enrdf_load_stackoverflow) | 1991-03-15 |
| IT1221510B (it) | 1990-07-06 |
| IT8748421A0 (it) | 1987-09-25 |
| FR2604437A1 (fr) | 1988-04-01 |
| NL8702295A (nl) | 1988-04-18 |
| DK503787A (da) | 1988-03-27 |
| FI874211A7 (fi) | 1988-03-27 |
| DE3732457A1 (de) | 1988-03-31 |
| ES2008739A6 (es) | 1989-08-01 |
| GR871487B (en) | 1988-02-04 |
| FI874211A0 (fi) | 1987-09-25 |
| SE8703701L (sv) | 1988-03-27 |
| AU607937B2 (en) | 1991-03-21 |
| GB2197649B (en) | 1990-03-28 |
| HU201946B (en) | 1991-01-28 |
| NO874044L (no) | 1988-03-28 |
| DK503787D0 (da) | 1987-09-25 |
| BE1002248A5 (fr) | 1990-11-06 |
| ATA244087A (de) | 1991-02-15 |
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| MM3A | Annulment or lapse |
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