KR880001285A - 약용 서방 기제 - Google Patents

약용 서방 기제 Download PDF

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Publication number
KR880001285A
KR880001285A KR1019870007755A KR870007755A KR880001285A KR 880001285 A KR880001285 A KR 880001285A KR 1019870007755 A KR1019870007755 A KR 1019870007755A KR 870007755 A KR870007755 A KR 870007755A KR 880001285 A KR880001285 A KR 880001285A
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South Korea
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pharmaceutical composition
composition according
matrix
acrylic resin
center
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KR1019870007755A
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KR930008954B1 (ko
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오스락크 벤자민
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마르틴 그린
유로셀띠끄 소시에떼 아노님
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Application filed by 마르틴 그린, 유로셀띠끄 소시에떼 아노님 filed Critical 마르틴 그린
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

내용 없음

Description

약용 서방 기제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (16)

10 내지 18개의 탄소원자의 고급 지방족 알코올 및 상기 고급 지방족 알코올에 아크릴수지를 합한 중량의 약 10 내지 60중량%의 양의 약학적으로 허용 가능한 아크릴수지로 되어 있는 제어방출 중심 또는 매트릭스에 분산된 제약 활성제로 구성되는 것을 특징으로 하는 구강투여용 확장작용 제어 방출 제약 조성물.
제1항에 있어서, 상기 아크릴 수지가 약 15 내지 40중량%의 양인 것을 특징으로 하는 제약조성물.
제1항에 있어서, 상기 아크릴수지가 약 20 내지 35중량%의 양인 것을 특징으로 하는 제약조성물.
제1항에 있어서, 상기 중심 또는 매트릭스 또한 접합제를 함유하는 것을 특징으로 하는 제약조성물.
제4항에 있어서, 상기 중심 또는 매트릭스 또한 충전제를 함유하는 것을 특징으로 하는 제약조성물.
제5항에 있어서, 상기 중심 또는 매트릭스 또한 붕해재를 함유하는 것을 특징으로 하는 제약조성물.
제6항에 있어서, 상기 중심 또는 매트릭스 또한 윤활유를 함유하는 것을 특징으로 하는 제약조성물.
제1항에 있어서, 상기 중심 또는 매트릭스가 상기 조성물의 약 20 내지 40중량%로 구성되는 것을 특징으로 하는 제약조성물.
제1항에 있어서, 상기 제약 활성제가 수용성이 높은 것을 특징으로 하는 제약조성물.
제1항에 있어서, 상기 약제가 아미트리프탈린, 아트로핀, 클로트페니라민, 클로르프로미진, 코데인, 댁스브롬페니라민, 디페닐히드라민, 독실아민, 에페드린, 히오스시아민, 모르핀, 옥시코돈, 파파바린, 페닐프로판올아민, 프로프라놀올, 퀴니딘, 스코프라민, 테오필린 또는 티오리다진인것을 특징으로 하는 약제조성물.
10 내지 18개의 탄소원자의 공급지방족 알코올 및 상기 고급 지방족 알코올과 아크릴수지 중량이 약 10 내지 60중량%의 양으로 존재하는 약학적으로 허용 가능한 아클릴수지로 구성되는 것을 특징으로 하는 구강 투여용 제어방출 약학조성물 및 그의 제약 활성제 분배에 알맞는 중심 또는 매트릭스.
제11항에 있어서, 상기 아크릴수지의 양이 약 15 내지 40중량%인 것을 특징으로 하는 중심 또는 매트릭스.
제11항에 있어서, 상기 아크릴수지의 양이 약 20 내지 35중량%인 것을 특징으로 하는 중심 또는 매트릭스.
제1항에 있어서, 정제형으로 존재하는 것을 특징으로 하는 제약조성물.
제1항에 있어서, 개프렛형으로 존재하는 것을 특징으로 하는 제약조성물.
제1항에 있어서, 캡슐형으로 존재하는 것을 특징으로 하는 제약조성물.
※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870007755A 1986-07-18 1987-07-16 약용 서방 기제 KR930008954B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US887340 1986-07-18
US06/887,340 US4861598A (en) 1986-07-18 1986-07-18 Controlled release bases for pharmaceuticals
US887,340 1986-07-18

Publications (2)

Publication Number Publication Date
KR880001285A true KR880001285A (ko) 1988-04-22
KR930008954B1 KR930008954B1 (ko) 1993-09-17

Family

ID=25390936

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870007755A KR930008954B1 (ko) 1986-07-18 1987-07-16 약용 서방 기제

Country Status (22)

Country Link
US (1) US4861598A (ko)
EP (1) EP0253104B1 (ko)
JP (2) JP2511054B2 (ko)
KR (1) KR930008954B1 (ko)
CN (1) CN1029770C (ko)
AT (1) ATE62404T1 (ko)
AU (1) AU596183B2 (ko)
CA (1) CA1296633C (ko)
DE (1) DE3769221D1 (ko)
DK (1) DK175627B1 (ko)
DZ (1) DZ1112A1 (ko)
EG (1) EG18574A (ko)
ES (1) ES2033259T3 (ko)
FI (1) FI87045C (ko)
GR (1) GR3001788T3 (ko)
IL (1) IL82604A (ko)
IN (1) IN166546B (ko)
MX (1) MX163284A (ko)
NO (1) NO169998C (ko)
NZ (1) NZ220406A (ko)
PT (1) PT85353B (ko)
ZA (1) ZA874038B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230000634U (ko) 2021-09-16 2023-03-23 장상환 분리가능한 쇠스랑

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EP0253104B1 (en) 1991-04-10
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CA1296633C (en) 1992-03-03
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EG18574A (en) 1993-08-30
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ES2033259T3 (es) 1993-03-16
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NO872989D0 (no) 1987-07-17
DE3769221D1 (de) 1991-05-16
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US4861598A (en) 1989-08-29
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PT85353B (pt) 1990-04-30
IL82604A0 (en) 1987-11-30
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ZA874038B (en) 1987-12-04
FI87045C (fi) 1992-11-25
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EP0253104A1 (en) 1988-01-20
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DK175627B1 (da) 2004-12-27
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GR3001788T3 (en) 1992-11-23
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CN1029770C (zh) 1995-09-20
DK367687A (da) 1988-01-19

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