KR870000867B1 - 소르비닐의 제조방법 - Google Patents

소르비닐의 제조방법 Download PDF

Info

Publication number
KR870000867B1
KR870000867B1 KR1019830005294A KR830005294A KR870000867B1 KR 870000867 B1 KR870000867 B1 KR 870000867B1 KR 1019830005294 A KR1019830005294 A KR 1019830005294A KR 830005294 A KR830005294 A KR 830005294A KR 870000867 B1 KR870000867 B1 KR 870000867B1
Authority
KR
South Korea
Prior art keywords
salt
sorbvinyl
solution
sorbin
quinine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019830005294A
Other languages
English (en)
Korean (ko)
Other versions
KR840006806A (ko
Inventor
2세 버컬리 웬델 규
디어트리치하멘 필립
사젼트 마세트 스테펜
쉴드즈 무어 버나드
죤 시스코 로버트
Original Assignee
화이자 인코포레이티드
윌리엄 데이비스 휸
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/440,641 external-priority patent/US4435578A/en
Priority claimed from US06/440,657 external-priority patent/US4431828A/en
Application filed by 화이자 인코포레이티드, 윌리엄 데이비스 휸 filed Critical 화이자 인코포레이티드
Publication of KR840006806A publication Critical patent/KR840006806A/ko
Priority to KR1019870002478A priority Critical patent/KR870000910B1/ko
Priority to KR1019870002477A priority patent/KR870000909B1/ko
Application granted granted Critical
Publication of KR870000867B1 publication Critical patent/KR870000867B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
KR1019830005294A 1982-11-10 1983-11-08 소르비닐의 제조방법 Expired KR870000867B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1019870002478A KR870000910B1 (ko) 1982-11-10 1987-03-19 6-플루오로-4-크로마논을 재생시키는 방법
KR1019870002477A KR870000909B1 (ko) 1982-11-10 1987-03-29 결정성 s-6-플루오로-4-우레이도크로만-4-카복실산염의 제조방법

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US44068682A 1982-11-10 1982-11-10
US440641 1982-11-10
US06/440,641 US4435578A (en) 1982-11-10 1982-11-10 Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US440686 1982-11-10
US06/440,657 US4431828A (en) 1982-11-10 1982-11-10 Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil
US44657 1982-11-10
US440657 1982-11-10

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1019870002478A Division KR870000910B1 (ko) 1982-11-10 1987-03-19 6-플루오로-4-크로마논을 재생시키는 방법
KR1019870002477A Division KR870000909B1 (ko) 1982-11-10 1987-03-29 결정성 s-6-플루오로-4-우레이도크로만-4-카복실산염의 제조방법

Publications (2)

Publication Number Publication Date
KR840006806A KR840006806A (ko) 1984-12-03
KR870000867B1 true KR870000867B1 (ko) 1987-04-30

Family

ID=27412063

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830005294A Expired KR870000867B1 (ko) 1982-11-10 1983-11-08 소르비닐의 제조방법

Country Status (16)

Country Link
KR (1) KR870000867B1 (enrdf_load_stackoverflow)
AU (1) AU540399B2 (enrdf_load_stackoverflow)
BG (1) BG44206A3 (enrdf_load_stackoverflow)
CS (1) CS266560B2 (enrdf_load_stackoverflow)
DD (1) DD213924A5 (enrdf_load_stackoverflow)
DK (1) DK512683A (enrdf_load_stackoverflow)
ES (3) ES8506040A1 (enrdf_load_stackoverflow)
FI (1) FI77247C (enrdf_load_stackoverflow)
GR (1) GR79017B (enrdf_load_stackoverflow)
IL (2) IL70165A (enrdf_load_stackoverflow)
NO (1) NO161916C (enrdf_load_stackoverflow)
NZ (1) NZ206189A (enrdf_load_stackoverflow)
PL (1) PL139713B1 (enrdf_load_stackoverflow)
PT (1) PT77617B (enrdf_load_stackoverflow)
SU (1) SU1209030A3 (enrdf_load_stackoverflow)
YU (2) YU44867B (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
ES534920A0 (es) 1985-09-16
YU44867B (en) 1991-04-30
YU140985A (en) 1986-04-30
NZ206189A (en) 1987-06-30
NO834086L (no) 1984-05-11
DD213924A5 (de) 1984-09-26
PT77617B (en) 1986-05-12
ES527118A0 (es) 1985-06-16
CS827183A2 (en) 1989-04-14
SU1209030A3 (ru) 1986-01-30
AU2110583A (en) 1984-05-17
YU220383A (en) 1988-02-29
FI834088A0 (fi) 1983-11-08
YU43883B (en) 1989-12-31
GR79017B (enrdf_load_stackoverflow) 1984-10-02
FI834088L (fi) 1984-05-11
IL70165A (en) 1987-12-20
IL81648A0 (en) 1987-09-16
DK512683D0 (da) 1983-11-09
ES534921A0 (es) 1985-06-16
NO161916B (no) 1989-07-03
PT77617A (en) 1983-12-01
ES8600269A1 (es) 1985-09-16
AU540399B2 (en) 1984-11-15
ES8506040A1 (es) 1985-06-16
PL244460A1 (en) 1985-03-26
CS266560B2 (en) 1990-01-12
DK512683A (da) 1984-05-11
FI77247B (fi) 1988-10-31
IL70165A0 (en) 1984-02-29
PL139713B1 (en) 1987-02-28
NO161916C (no) 1989-10-11
ES8505988A1 (es) 1985-06-16
KR840006806A (ko) 1984-12-03
BG44206A3 (bg) 1988-10-14
FI77247C (fi) 1989-02-10

Similar Documents

Publication Publication Date Title
GB2025968A (en) 6 - methoxy - - methyl - 2 naphthalene-acetic acid resolution
US4562263A (en) Process for producing 3-(3,4-dihydroxyphenyl) serine
US5621140A (en) Resolution of ibuprofen
KR870000867B1 (ko) 소르비닐의 제조방법
EP0109231B1 (en) Sorbinil by optical resolution with aminopinane derivatives
US4191828A (en) Process for preparing 2-(2,2-dicyclohexylethyl)piperidine
US4435578A (en) Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
US4395571A (en) Process for the preparation of d,1-2-(6-methoxy-2-naphthyl)propionic acid
US4431828A (en) Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil
US5578734A (en) Method for the preparation of S-(+)-ethodolic acid and saline derivatives
US5087698A (en) Process for the optical resolution of dropopizine
US4528387A (en) Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
KR870000909B1 (ko) 결정성 s-6-플루오로-4-우레이도크로만-4-카복실산염의 제조방법
JP3084577B2 (ja) 光学活性なアトロラクチン酸の製造方法および製造の中間体
KR870000584B1 (ko) 6-플루오로-4-우레이도크로만-4-카복실산으로부터 6-플루오로-4-크로만온의 재생방법
JPH0374384A (ja) ３ｒ‐（３‐カルボキシベンジル）‐６‐（５‐フルオロ‐２‐ベンゾチアゾリル）メトキシ‐４ｒ‐クロマノールの光学分割方法
JPS5942674B2 (ja) Ｎ−（４′−クロロ−３′−スルフアモイルベンゼンスルホニル）−ｎ−メチル−２−アミノメチル−２−メチル−テトラヒドロフランの製造方法
SU406355A1 (enrdf_load_stackoverflow)
US4386205A (en) Resolution of racemic 5-phenyl-2-pentanol
JPH01180867A (ja) 光学分割法
EP0118934A1 (en) Optically active alpha-azido-p-hydroxyphenylacetic acid and its salts, and the preparation thereof
JPH07157475A (ja) （＋）−３−フェニル−５−｛２−（１−ピロリジニルメチル）ブチリル｝イソオキサゾール及びその塩の分割法
HK1006309B (en) A process for the optical resolution of dropropizine
NZ216928A (en) Sorbinil by optical resolution of precursor 6- fluoro -4- ureidochroman -4-ylcarboxylic acid and certain amine salts of this precursor acid

Legal Events

Date Code Title Description
A201 Request for examination
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

FPAY Annual fee payment

Payment date: 19920305

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19930501

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19930501

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

P22-X000 Classification modified

St.27 status event code: A-4-4-P10-P22-nap-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000