BG44206A3 - Метод за получаване на сорбинил - Google Patents
Метод за получаване на сорбинилInfo
- Publication number
- BG44206A3 BG44206A3 BG062988A BG6298883A BG44206A3 BG 44206 A3 BG44206 A3 BG 44206A3 BG 062988 A BG062988 A BG 062988A BG 6298883 A BG6298883 A BG 6298883A BG 44206 A3 BG44206 A3 BG 44206A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- sorbinil
- obtaining
- aminopinane
- crystallization
- avoids
- Prior art date
Links
- LXANPKRCLVQAOG-NSHDSACASA-N sorbinil Chemical compound C12=CC(F)=CC=C2OCC[C@@]21NC(=O)NC2=O LXANPKRCLVQAOG-NSHDSACASA-N 0.000 title abstract 3
- 229950004311 sorbinil Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- VPTSZLVPZCTAHZ-UHFFFAOYSA-N 4,6,6-trimethylbicyclo[3.1.1]heptan-3-amine Chemical class C1C(N)C(C)C2C(C)(C)C1C2 VPTSZLVPZCTAHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940118148 Aldose reductase inhibitor Drugs 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44068682A | 1982-11-10 | 1982-11-10 | |
| US06/440,641 US4435578A (en) | 1982-11-10 | 1982-11-10 | Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid |
| US06/440,657 US4431828A (en) | 1982-11-10 | 1982-11-10 | Regeneration of 6-fluoro-4-chromanone from by-products in the synthesis of sorbinil |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG44206A3 true BG44206A3 (bg) | 1988-10-14 |
Family
ID=27412063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG062988A BG44206A3 (bg) | 1982-11-10 | 1983-11-09 | Метод за получаване на сорбинил |
Country Status (16)
-
1983
- 1983-11-07 PT PT77617A patent/PT77617B/pt not_active IP Right Cessation
- 1983-11-07 YU YU2203/83A patent/YU44867B/xx unknown
- 1983-11-07 GR GR72904A patent/GR79017B/el unknown
- 1983-11-08 ES ES527118A patent/ES8506040A1/es not_active Expired
- 1983-11-08 FI FI834088A patent/FI77247C/fi not_active IP Right Cessation
- 1983-11-08 DD DD83256455A patent/DD213924A5/de not_active IP Right Cessation
- 1983-11-08 PL PL1983244460A patent/PL139713B1/pl unknown
- 1983-11-08 IL IL70165A patent/IL70165A/xx unknown
- 1983-11-08 KR KR1019830005294A patent/KR870000867B1/ko not_active Expired
- 1983-11-08 NZ NZ206189A patent/NZ206189A/en unknown
- 1983-11-09 DK DK512683A patent/DK512683A/da not_active Application Discontinuation
- 1983-11-09 BG BG062988A patent/BG44206A3/xx unknown
- 1983-11-09 NO NO834086A patent/NO161916C/no unknown
- 1983-11-09 AU AU21105/83A patent/AU540399B2/en not_active Ceased
- 1983-11-09 SU SU833659625A patent/SU1209030A3/ru active
- 1983-11-09 CS CS838271A patent/CS266560B2/cs unknown
-
1984
- 1984-08-06 ES ES534921A patent/ES8505988A1/es not_active Expired
- 1984-08-06 ES ES534920A patent/ES534920A0/es active Granted
-
1985
- 1985-09-09 YU YU1409/85A patent/YU43883B/xx unknown
-
1987
- 1987-02-23 IL IL81648A patent/IL81648A0/xx not_active IP Right Cessation
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