KR850000273B1 - 9-아미노-1-하이드록 시옥타하이드로 벤조[c] 퀴놀린의 제조 방법 - Google Patents

9-아미노-1-하이드록 시옥타하이드로 벤조[c] 퀴놀린의 제조 방법 Download PDF

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Publication number
KR850000273B1
KR850000273B1 KR1019810002717A KR810002717A KR850000273B1 KR 850000273 B1 KR850000273 B1 KR 850000273B1 KR 1019810002717 A KR1019810002717 A KR 1019810002717A KR 810002717 A KR810002717 A KR 810002717A KR 850000273 B1 KR850000273 B1 KR 850000273B1
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KR
South Korea
Prior art keywords
methyl
hydroxy
mixture
ether
compound
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Expired
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KR1019810002717A
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English (en)
Korean (ko)
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KR830006217A (ko
Inventor
로스 죤슨 미카엘
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화이자 인코포레이티드
윌리암 지. 멕크리리
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes
    • C07D221/12—Phenanthridines

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
KR1019810002717A 1980-07-28 1981-07-27 9-아미노-1-하이드록 시옥타하이드로 벤조[c] 퀴놀린의 제조 방법 Expired KR850000273B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/173,207 US4309545A (en) 1980-07-28 1980-07-28 Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US173,207 1980-07-28

Publications (2)

Publication Number Publication Date
KR830006217A KR830006217A (ko) 1983-09-20
KR850000273B1 true KR850000273B1 (ko) 1985-03-15

Family

ID=22630983

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810002717A Expired KR850000273B1 (ko) 1980-07-28 1981-07-27 9-아미노-1-하이드록 시옥타하이드로 벤조[c] 퀴놀린의 제조 방법

Country Status (29)

Country Link
US (1) US4309545A (enExample)
EP (1) EP0045171B1 (enExample)
JP (1) JPS57112372A (enExample)
KR (1) KR850000273B1 (enExample)
AR (1) AR230988A1 (enExample)
AT (1) ATE11775T1 (enExample)
AU (1) AU525944B2 (enExample)
CA (1) CA1178274A (enExample)
CS (1) CS228515B2 (enExample)
DD (1) DD202012A5 (enExample)
DE (1) DE3168891D1 (enExample)
DK (1) DK334581A (enExample)
EG (1) EG15535A (enExample)
ES (1) ES8301926A1 (enExample)
FI (1) FI812338A7 (enExample)
GR (1) GR75283B (enExample)
GT (1) GT198170557A (enExample)
HU (1) HU185133B (enExample)
IE (1) IE51426B1 (enExample)
IL (1) IL63423A0 (enExample)
IN (1) IN158867B (enExample)
NO (2) NO812557L (enExample)
NZ (1) NZ197856A (enExample)
PH (1) PH17281A (enExample)
PL (1) PL133928B1 (enExample)
PT (1) PT73440B (enExample)
SU (1) SU1217254A3 (enExample)
YU (1) YU185181A (enExample)
ZA (1) ZA815128B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642373A (en) * 1982-03-16 1987-02-10 Pfizer Inc. Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4473704A (en) * 1982-03-16 1984-09-25 Pfizer Inc. Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta[1]phenanthrenes, decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines as CNS agents
US4920221A (en) * 1982-03-16 1990-04-24 Pfizer Inc. Substituted decahydro-1H-pyrido[1,2-f]phenanthridines and decahydropyrrolo[1,2-f]phenanthridines
US5605906A (en) * 1995-03-24 1997-02-25 Merck Frosst Canada, Inc. Cannabinoid receptor agonists
HU221380B1 (en) * 1996-01-31 2002-09-28 Byk Gulden Lomberg Chem Fab Phosphodiesterase inhibitor phenanthridines derivatives and use thereof
DK0889886T5 (da) * 1996-03-26 2003-02-24 Altana Pharma Ag Hidtil ukendte, i 6-stilling substituerede phenanthridiner
US6127378A (en) * 1996-03-26 2000-10-03 Byk Gulden Lomberg Chemische Fabrik Gmbh Phenanthridines substituted in the 6 position
US5776482A (en) * 1996-03-29 1998-07-07 University Of Iowa Research Foundation Tetrahydroquinoline analogues for use in glaucoma treatment
PL191094B1 (pl) * 1997-07-25 2006-03-31 Altana Pharma Ag Nowe podstawione 6-fenylofenantrydyny, środek farmaceutyczny zawierający te pochodne oraz ich zastosowanie
ES2184318T3 (es) * 1997-07-25 2003-04-01 Altana Pharma Ag 6-alquilfenantridinas sustituidas.
AU3910700A (en) 1999-03-22 2000-10-09 Immugen Pharmaceuticals, Inc. Treatment of immune diseases
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US20060084021A1 (en) * 2004-09-10 2006-04-20 Kubicek Chris A Wick holder
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2003080043A1 (en) * 2002-03-18 2003-10-02 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
CN1964711A (zh) * 2004-05-25 2007-05-16 奥特拉药物公司 眼睛选择性药物及前体药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3839441A (en) * 1969-10-27 1974-10-01 Hoffmann La Roche Intermediates for partially hydrogenated phenanthridines
US3878219A (en) * 1973-07-13 1975-04-15 Abbott Lab 5H-{8 1{9 benzopyrano{8 3,4-d{9 pyridines
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
HU180916B (hu) 1976-05-17 1983-05-30 Pfizer Eljárás benzo[c]kinolin-származékok előállítására
US4152450A (en) * 1978-02-17 1979-05-01 Eli Lilly And Company 9-Amino-dibenzopyrans

Also Published As

Publication number Publication date
CA1178274A (en) 1984-11-20
GR75283B (enExample) 1984-07-13
AU525944B2 (en) 1982-12-09
EG15535A (en) 1986-09-30
PT73440B (en) 1983-06-20
IN158867B (enExample) 1987-02-07
ZA815128B (en) 1982-07-28
GT198170557A (es) 1983-01-12
KR830006217A (ko) 1983-09-20
PL232331A1 (en) 1983-09-26
FI812338L (fi) 1982-01-29
ATE11775T1 (de) 1985-02-15
FI812338A7 (fi) 1982-01-29
IE811686L (en) 1982-01-28
SU1217254A3 (ru) 1986-03-07
US4309545A (en) 1982-01-05
ES504323A0 (es) 1982-12-16
PT73440A (en) 1981-08-01
HU185133B (en) 1984-12-28
AU7343481A (en) 1982-05-06
CS228515B2 (en) 1984-05-14
DK334581A (da) 1982-01-29
DE3168891D1 (en) 1985-03-28
NO812557L (no) 1982-01-29
AR230988A1 (es) 1984-08-31
PH17281A (en) 1984-07-06
EP0045171A2 (en) 1982-02-03
YU185181A (en) 1983-12-31
NO854454L (no) 1985-01-29
JPS57112372A (en) 1982-07-13
DD202012A5 (de) 1983-08-24
PL133928B1 (en) 1985-07-31
ES8301926A1 (es) 1982-12-16
EP0045171A3 (en) 1982-04-28
EP0045171B1 (en) 1985-02-13
IL63423A0 (en) 1981-10-30
IE51426B1 (en) 1986-12-24
NZ197856A (en) 1984-10-19

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