KR840005483A - A47934 항생물질의 제조방법 - Google Patents

A47934 항생물질의 제조방법 Download PDF

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Publication number
KR840005483A
KR840005483A KR1019830003099A KR830003099A KR840005483A KR 840005483 A KR840005483 A KR 840005483A KR 1019830003099 A KR1019830003099 A KR 1019830003099A KR 830003099 A KR830003099 A KR 830003099A KR 840005483 A KR840005483 A KR 840005483A
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KR
South Korea
Prior art keywords
antibiotic
antibiotics
preparation
streptomyces toyocaensis
medium
Prior art date
Application number
KR1019830003099A
Other languages
English (en)
Other versions
KR860001231B1 (ko
Inventor
엘. 헤밀(외 1) 로버트
Original Assignee
아더 알. 웨일
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아더 알. 웨일, 일라이 릴리 앤드 캄파니 filed Critical 아더 알. 웨일
Publication of KR840005483A publication Critical patent/KR840005483A/ko
Application granted granted Critical
Publication of KR860001231B1 publication Critical patent/KR860001231B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Abstract

내용 없음

Description

A47934 항생물질의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 항생물질 A47934의 적외선 흡수 스펙트럼(KBr법)을 나타내는 도.

Claims (3)

  1. 스트렙토마이세스 토요카엔시스 NRRL 15009(KFCC 10042), 또는 그의 A47934-생성 변종 또는 돌연변이체를 액침 호기성 발효 조건하, 탄소, 질소 및 무기염류의 동화원을 함유하는 배지중에서 배양함을 특징으로 하여, 다음 구조식(I)의 항생물질 A47934 또는 그의 약학적으로 허용되는 염을 제조하는 방법.
  2. 제1항에 있어서, 계속해서 배지로부터 A47934 항생물질을 분리하는 방법.
  3. 제1항 또는 2항에 있어서,스트렙토마이세스 토요카엔시스NRRL 15009를 배양하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830003099A 1982-07-30 1983-07-07 A47934 항생물질의 제조방법 KR860001231B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/403,842 US4462942A (en) 1982-07-30 1982-07-30 A47934 Antibiotic and process for production thereof
US403,842 1982-07-30
US403842 1982-07-30

Publications (2)

Publication Number Publication Date
KR840005483A true KR840005483A (ko) 1984-11-14
KR860001231B1 KR860001231B1 (ko) 1986-08-30

Family

ID=23597185

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830003099A KR860001231B1 (ko) 1982-07-30 1983-07-07 A47934 항생물질의 제조방법

Country Status (23)

Country Link
US (1) US4462942A (ko)
EP (1) EP0100605B1 (ko)
JP (1) JPS5929621A (ko)
KR (1) KR860001231B1 (ko)
AR (1) AR231842A1 (ko)
AT (1) ATE22802T1 (ko)
AU (1) AU557782B2 (ko)
CA (1) CA1202261A (ko)
CS (1) CS235045B2 (ko)
DD (1) DD210072A5 (ko)
DE (1) DE3366836D1 (ko)
DK (1) DK310683A (ko)
ES (1) ES8504250A1 (ko)
FI (1) FI832429L (ko)
GB (1) GB2124620B (ko)
GR (1) GR77578B (ko)
HU (1) HU192162B (ko)
IL (1) IL69142A0 (ko)
NZ (1) NZ204800A (ko)
PL (1) PL242777A1 (ko)
PT (1) PT77007B (ko)
RO (1) RO86844B (ko)
ZA (1) ZA834938B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537879A (en) * 1982-07-30 1985-08-27 Eli Lilly And Company A47934 Antibiotic and process for production thereof
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8415092D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Ester derivatives
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
IL78597A0 (en) * 1985-04-25 1986-08-31 Lilly Co Eli Novel glycopeptide derivatives
GB8608798D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Recovery of glycopeptide antibiotics from aqueous solutions
US4742045A (en) * 1986-07-30 1988-05-03 Smithkline Beckman Corporation Glycopeptide antibiotics
US4880735A (en) * 1986-09-24 1989-11-14 Eli Lilly And Company Process for producing antibiotic A47934
GB8624806D0 (en) * 1986-10-16 1986-11-19 Pfizer Ltd Glycopeptide antibiotic
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process
CA1336811C (en) * 1988-03-30 1995-08-29 James Baber Rowe Treatment of equine livestock with antibiotics
US7570028B2 (en) * 2007-04-26 2009-08-04 Advanced Energy Industries, Inc. Method and apparatus for modifying interactions between an electrical generator and a nonlinear load
US8716984B2 (en) 2009-06-29 2014-05-06 Advanced Energy Industries, Inc. Method and apparatus for modifying the sensitivity of an electrical generator to a nonlinear load
EA030750B1 (ru) * 2013-03-15 2018-09-28 Мериал, Инк. Противомикробная полиамидная композиция и способ лечения мастита
FR3013436B1 (fr) * 2013-11-18 2018-12-07 Valeo Systemes Thermiques Collecteur pour echangeur de chaleur
PL410247A1 (pl) * 2014-11-25 2016-06-06 Jamroży Marek Bio-Koncept Sposób sanityzacji otoczenia mikrobiologicznego

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB765886A (en) * 1953-08-11 1957-01-16 Abbott Lab A new antibiotic ristocetin and a method of producing same
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
US3338786A (en) * 1966-07-29 1967-08-29 American Cyanamid Co Antibiotic av290 and production thereof
US3952095A (en) * 1972-06-02 1976-04-20 Eli Lilly And Company Novel antibiotic and a process for the production thereof
JPS5831196B2 (ja) * 1975-10-29 1983-07-04 明治製菓株式会社 Ｓｆ−１７７１ ブツシツノ セイゾウホウ
US4322406A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1
US4322343A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Pseudo-aglycone of actaplanin

Also Published As

Publication number Publication date
DE3366836D1 (en) 1986-11-20
AU1649383A (en) 1984-02-02
CS235045B2 (en) 1985-04-16
EP0100605B1 (en) 1986-10-15
AU557782B2 (en) 1987-01-08
FI832429A0 (fi) 1983-07-01
GB2124620A (en) 1984-02-22
JPS5929621A (ja) 1984-02-16
PT77007A (en) 1983-08-01
HU192162B (en) 1987-05-28
RO86844B (ro) 1985-05-31
DK310683D0 (da) 1983-07-05
FI832429L (fi) 1984-01-31
JPH0443079B2 (ko) 1992-07-15
GB2124620B (en) 1985-11-27
ES523761A0 (es) 1985-04-16
ZA834938B (en) 1984-03-28
NZ204800A (en) 1987-02-20
US4462942A (en) 1984-07-31
ES8504250A1 (es) 1985-04-16
DD210072A5 (de) 1984-05-30
PL242777A1 (en) 1984-08-13
AR231842A1 (es) 1985-03-29
PT77007B (en) 1986-04-11
GR77578B (ko) 1984-09-24
DK310683A (da) 1984-01-31
RO86844A (ro) 1985-05-20
GB8318056D0 (en) 1983-08-03
KR860001231B1 (ko) 1986-08-30
EP0100605A1 (en) 1984-02-15
IL69142A0 (en) 1983-11-30
ATE22802T1 (de) 1986-11-15
CA1202261A (en) 1986-03-25

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