KR850003165A - 항생물질 착화물 - Google Patents
항생물질 착화물 Download PDFInfo
- Publication number
- KR850003165A KR850003165A KR1019840006102A KR840006102A KR850003165A KR 850003165 A KR850003165 A KR 850003165A KR 1019840006102 A KR1019840006102 A KR 1019840006102A KR 840006102 A KR840006102 A KR 840006102A KR 850003165 A KR850003165 A KR 850003165A
- Authority
- KR
- South Korea
- Prior art keywords
- bbm
- host
- antibiotic
- culture medium
- producing
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title claims 4
- MGQRRMONVLMKJL-KWJIQSIXSA-N elsamitrucin Chemical compound O1[C@H](C)[C@H](O)[C@H](OC)[C@@H](N)[C@H]1O[C@@H]1[C@](O)(C)[C@@H](O)[C@@H](C)O[C@H]1OC1=CC=CC2=C(O)C(C(O3)=O)=C4C5=C3C=CC(C)=C5C(=O)OC4=C12 MGQRRMONVLMKJL-KWJIQSIXSA-N 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 230000000844 anti-bacterial effect Effects 0.000 claims 4
- 239000001963 growth medium Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 235000015097 nutrients Nutrition 0.000 claims 2
- 239000008024 pharmaceutical diluent Substances 0.000 claims 2
- 102000001742 Tumor Suppressor Proteins Human genes 0.000 claims 1
- 108010040002 Tumor Suppressor Proteins Proteins 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 230000036210 malignancy Effects 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- OKKJLVBELUTLKV-MZCSYVLQSA-N Deuterated methanol Chemical compound [2H]OC([2H])([2H])[2H] OKKJLVBELUTLKV-MZCSYVLQSA-N 0.000 description 2
- 238000000862 absorption spectrum Methods 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N DMSO Substances CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A63—SPORTS; GAMES; AMUSEMENTS
- A63H—TOYS, e.g. TOPS, DOLLS, HOOPS OR BUILDING BLOCKS
- A63H33/00—Other toys
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Toys (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 BBM-2748A의 적외선 흡수스펙트럼을 나타낸다.
제2도는 BBM-2748B의 적외선 흡수 스팩트럼을 나타낸다.
제3도는 CD3OD에서의 BBM-24788A이 양자 자기공명 스펙트럼(80MHz)을 나타낸다.
제4도는 d6-DMSO에서의 BBN-2478A의13C핵자기공명 스팩트럼을 나타낸다.
Claims (10)
- 일반식을 갖는 항생제 BBM-2748A
- 일반식을 갖는 항생제 BBM-2478B
- BBM-2478A의 실질적인 량을 상기 배양배지에 있는 상기 세균에 의하여 생성시킨 다음 그 배양배지에서 BBM-2478A를 회수할 때까지 침수 호기 조건하에 동화할 수 있는 탄소 및 질소원을 함유하는 수용성 영양배지에서 균주 J 907-21(ATCC39417)이나 이들의 돌연변이체를 생성하는 BBM-2478 A를 배양하는 것으로 구성되는 항생물질BBM-2478A를 생성하는 방법.
- BBM-2478B의 실질적인 량을 상기 배양배지에 있는 상기 세균에 의하여 생성시킨 다음 그 배양배지에서 BBM-2478 B를 회수할때까지 침수 호기 조건하에 동화할 수 있는 탄소 및 질소원을 함유하는 수용성 영양배지에서 균주 J 907-21(ATCC39417)이나 이들의 돌연변이체를 생성하는 BBM-2478B를 배양하는 것으로 구성되는 항생물질 BBM-2478B를 생성하는 방법.
- BBM-2478A의 효과적인 항박테리아 투여량을 상기 숙주에 투여하는 것으로 구성되는 박테리아 감염에 걸린 동물숙주를 치료학적으로 처치하는 방법.
- BBM-2478B의 효과적인 항박테리아 투여량을 상기 숙주에 투여하는 것으로 구성되는 박테리아 감염에 걸린 동물숙주를 치료학적으로 처치하는 방법.
- BBM-2478A의 효과적인 종양-억제 투여량을 상기 숙주에 투여하는 것으로 이루어진 악성종양에 걸린 포유동물 숙주를 치료학적으로 처치하는 방법.
- 효과적인 항박테리아량의 BBM-2478A가 약제상 담체나 희석제와 함께 결합하는 것으로 구성되는 제약상조성물.
- 효과적인 항박테리아량의 BBM-2478B가 제약상 담체나 희석제와 함께 결합하는 것으로 구성되는 제약상 조성물.
- 효과적인 종양억제량의 BBM-2478B가 제약상 담채나 희석제와 함께 결합하는 것으로 구성되는 제약상 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/538,543 US4573936A (en) | 1983-10-03 | 1983-10-03 | Driving toy |
US538453 | 1983-10-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR850003165A true KR850003165A (ko) | 1985-06-13 |
KR920001448B1 KR920001448B1 (ko) | 1992-02-14 |
Family
ID=24147345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840006102A KR920001448B1 (ko) | 1983-10-03 | 1984-10-02 | Bbm-2478 항생제 착화합물 |
Country Status (2)
Country | Link |
---|---|
US (1) | US4573936A (ko) |
KR (1) | KR920001448B1 (ko) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4932913A (en) * | 1988-02-05 | 1990-06-12 | Roni Raviv | Child's simulated vehicle control device |
US5272932A (en) * | 1992-05-28 | 1993-12-28 | The United States Of America As Represented By The Secretary Of The Navy | Torsional device for remote control steering system |
US6805604B2 (en) * | 2001-11-02 | 2004-10-19 | Mattel, Inc. | Toy driving simulator |
US20030162597A1 (en) * | 2002-02-27 | 2003-08-28 | Tek Nek Toys International, Inc. | Interactive playset |
US7682218B2 (en) * | 2006-09-20 | 2010-03-23 | Mattel, Inc. | Toy vehicle and launcher |
US20080070197A1 (en) * | 2006-09-20 | 2008-03-20 | Mattel, Inc. | Interactive toy vehicle cockpit |
US10130191B2 (en) | 2015-09-09 | 2018-11-20 | Kids Ii, Inc. | Convertible children's walker |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1532595A (en) * | 1923-04-09 | 1925-04-07 | George L Mcmannis | Mechanical toy |
US1942514A (en) * | 1932-07-26 | 1934-01-09 | Frank J Mayer | Mechanical toy |
FR949366A (fr) * | 1947-07-15 | 1949-08-29 | Manège-jouet démontable | |
FR1081483A (fr) * | 1953-07-21 | 1954-12-20 | Manège-jouet opérant successivement la giration, le piqué et la remontée d'avionssilhouettes | |
FR1123908A (fr) * | 1955-03-24 | 1956-10-01 | Dispositif d'entraînement pour jouets, modèles réduits ou analogues et articles munis de ce dispositif | |
US2901251A (en) * | 1955-07-06 | 1959-08-25 | Pettit Frank | Airplane toys |
US2792224A (en) * | 1956-02-10 | 1957-05-14 | White Amanda Lillian | Jumping rabbit and egg pull game |
US3525175A (en) * | 1965-10-11 | 1970-08-25 | Tobin Wolf | Toy simulating realistic driving conditions |
US3657457A (en) * | 1969-09-22 | 1972-04-18 | Donald B Poynter | Apparatus for testing driving skill |
US3984105A (en) * | 1974-07-29 | 1976-10-05 | Marvin Glass & Associates | Game apparatus |
-
1983
- 1983-10-03 US US06/538,543 patent/US4573936A/en not_active Expired - Fee Related
-
1984
- 1984-10-02 KR KR1019840006102A patent/KR920001448B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR920001448B1 (ko) | 1992-02-14 |
US4573936A (en) | 1986-03-04 |
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E902 | Notification of reason for refusal | ||
G160 | Decision to publish patent application | ||
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FPAY | Annual fee payment |
Payment date: 19970206 Year of fee payment: 6 |
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LAPS | Lapse due to unpaid annual fee |