GB1512568A - Antibiotic a-28086 and process for production thereof - Google Patents

Antibiotic a-28086 and process for production thereof

Info

Publication number
GB1512568A
GB1512568A GB24030/75A GB2403075A GB1512568A GB 1512568 A GB1512568 A GB 1512568A GB 24030/75 A GB24030/75 A GB 24030/75A GB 2403075 A GB2403075 A GB 2403075A GB 1512568 A GB1512568 A GB 1512568A
Authority
GB
United Kingdom
Prior art keywords
antibiotic
factors
culture medium
novel antibiotic
converted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24030/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/569,740 external-priority patent/US4038384A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB1512568A publication Critical patent/GB1512568A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/195Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Feed For Specific Animals (AREA)
  • Medicinal Preparation (AREA)

Abstract

The novel antibiotic A-28086 complex containing the factors A, B and D is produced by culturing Streptomyces aureofaciens NRRL 5758 or Streptomyces aureofaciens NRRL 8092 in a culture medium, which contains assimilable sources for carbohydrate, nitrogen and inorganic salts, in submerged aerobic fermentation conditions until these organisms have produced a significant amount of antibiotic activity in the culture medium. The antibiotic is then separated off from the culture medium. The novel antibiotic can be dissociated into the factors A, B and D. These can be converted into the corresponding physiologically tolerated salts. The novel antibiotic can likewise be converted into C2-C6-acyl esters. The novel antibiotic A-28086 complex, the factors A, B and D, the physiologically tolerated salts thereof and also C2-C6-acyl esters thereof are used to increase the feed intake of ruminants. They can additionally be used for the prevention or treatment of coccidiosis in poultry.
GB24030/75A 1974-06-10 1975-06-04 Antibiotic a-28086 and process for production thereof Expired GB1512568A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47795474A 1974-06-10 1974-06-10
US56971975A 1975-04-21 1975-04-21
US05/569,740 US4038384A (en) 1974-06-10 1975-04-21 Antibiotic a-28086 and process for production thereof

Publications (1)

Publication Number Publication Date
GB1512568A true GB1512568A (en) 1978-06-01

Family

ID=27413429

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24030/75A Expired GB1512568A (en) 1974-06-10 1975-06-04 Antibiotic a-28086 and process for production thereof

Country Status (23)

Country Link
JP (1) JPS5836957B2 (en)
AR (1) AR207982A1 (en)
AU (1) AU497101B2 (en)
BG (2) BG28850A4 (en)
CH (1) CH621687A5 (en)
DD (2) DD122261A5 (en)
DE (1) DE2525095C2 (en)
DK (1) DK142061B (en)
EG (1) EG12589A (en)
ES (1) ES438422A1 (en)
FI (1) FI53837C (en)
FR (1) FR2273550A1 (en)
GB (1) GB1512568A (en)
HU (2) HU173603B (en)
IE (1) IE41079B1 (en)
IL (1) IL47426A (en)
NL (1) NL184575C (en)
NO (1) NO143030C (en)
PL (1) PL98635B1 (en)
RO (1) RO64706A (en)
SE (2) SE429763B (en)
SU (1) SU576966A3 (en)
YU (1) YU37359B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11026966B2 (en) 2018-05-02 2021-06-08 Purina Animal Nutrition Llc Animal feed products containing percarbonate and methods of feeding same

Also Published As

Publication number Publication date
CH621687A5 (en) 1981-02-27
NO143030B (en) 1980-08-25
SE7905655L (en) 1979-06-27
DE2525095A1 (en) 1975-12-18
PL98635B1 (en) 1978-05-31
SU576966A3 (en) 1977-10-15
JPS519788A (en) 1976-01-26
ES438422A1 (en) 1977-05-16
NO752033L (en) 1975-12-11
SE429763B (en) 1983-09-26
DK142061B (en) 1980-08-18
AU8181475A (en) 1976-12-09
DD122261A5 (en) 1976-09-20
YU145475A (en) 1983-04-27
NL184575C (en) 1989-09-01
RO64706A (en) 1980-03-15
SE7506509L (en) 1975-12-11
HU173603B (en) 1979-06-28
YU37359B (en) 1984-08-31
DK142061C (en) 1981-01-12
IL47426A (en) 1978-04-30
SE431153B (en) 1984-01-23
BG28269A3 (en) 1980-03-25
AR207982A1 (en) 1976-11-22
DK257975A (en) 1975-12-11
NO143030C (en) 1980-12-03
FR2273550A1 (en) 1976-01-02
DD127431A5 (en) 1977-09-21
EG12589A (en) 1979-06-30
FI751705A (en) 1975-12-11
JPS5836957B2 (en) 1983-08-12
NL7506920A (en) 1975-12-12
FI53837B (en) 1978-05-02
FR2273550B1 (en) 1978-11-10
BG28850A4 (en) 1980-07-15
FI53837C (en) 1978-08-10
IE41079L (en) 1975-12-10
AU497101B2 (en) 1978-11-30
HU174299B (en) 1979-12-28
IE41079B1 (en) 1979-10-10
IL47426A0 (en) 1975-08-31
DE2525095C2 (en) 1984-11-15

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
704A Declaration that licence is not available as of right for an excepted use (par. 4a/1977)
PE20 Patent expired after termination of 20 years

Effective date: 19950603