ES382658A1 - Antibiotic and process for preparing same - Google Patents

Antibiotic and process for preparing same

Info

Publication number
ES382658A1
ES382658A1 ES382658A ES382658A ES382658A1 ES 382658 A1 ES382658 A1 ES 382658A1 ES 382658 A ES382658 A ES 382658A ES 382658 A ES382658 A ES 382658A ES 382658 A1 ES382658 A1 ES 382658A1
Authority
ES
Spain
Prior art keywords
antibiotic
a16886ii
culture medium
preparing same
aerobes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES382658A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES382658A1 publication Critical patent/ES382658A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Fodder In General (AREA)

Abstract

A process for the production of antibiotic A16886I and/or antibiotic A16886II, or pharmaceutically acceptable salts thereof, which process is characterized by cultivating Streptomyces clavuligerus NRRL 3585 in a culture medium containing assimilable sources of carbon, nitrogen and inorganic salts, under conditions submerged aerobes, until a substantial amount of antibiotic A16886I and/or antibiotic A16886II is produced by said organism in said culture medium. (Machine-translation by Google Translate, not legally binding)
ES382658A 1969-08-12 1970-08-11 Antibiotic and process for preparing same Expired ES382658A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84939569A 1969-08-12 1969-08-12

Publications (1)

Publication Number Publication Date
ES382658A1 true ES382658A1 (en) 1972-11-01

Family

ID=25305685

Family Applications (2)

Application Number Title Priority Date Filing Date
ES382658A Expired ES382658A1 (en) 1969-08-12 1970-08-11 Antibiotic and process for preparing same
ES393985A Expired ES393985A1 (en) 1969-08-12 1971-08-06 Antibiotic and process for preparing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES393985A Expired ES393985A1 (en) 1969-08-12 1971-08-06 Antibiotic and process for preparing same

Country Status (24)

Country Link
JP (3) JPS4945594B1 (en)
AT (1) AT297932B (en)
BE (1) BE754693A (en)
BR (1) BR6915079D0 (en)
CA (1) CA954809A (en)
CH (3) CH594050A5 (en)
CS (2) CS184309B2 (en)
DE (1) DE2040141C3 (en)
DK (2) DK128017B (en)
ES (2) ES382658A1 (en)
FI (1) FI45990C (en)
FR (1) FR2068490B1 (en)
GB (1) GB1315177A (en)
IL (1) IL35065A (en)
NL (1) NL7011805A (en)
NO (1) NO132242C (en)
OA (1) OA03599A (en)
PH (1) PH12529A (en)
PL (1) PL84058B1 (en)
RO (1) RO58570A (en)
SE (2) SE384690B (en)
SU (1) SU511027A3 (en)
YU (1) YU36539B (en)
ZA (1) ZA705386B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1348985A (en) 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
DE2221035C2 (en) * 1972-04-28 1982-03-25 Merck & Co., Inc., 07065 Rahway, N.J. Process for the preparation of substituted 6-iminoopenicillins and 7-iminocephalosporins
ES444948A1 (en) 1975-02-07 1977-08-16 Glaxo Lab Ltd Pure potassium salt of clavulanic acid
US6218380B1 (en) * 1975-04-17 2001-04-17 Smithkline Beecham P.L.C. Pharmaceutical compositions
US6048977C1 (en) * 1975-04-17 2001-10-16 Smithkline Beecham Plc Clavulanic acid and salts thereof
US4529734A (en) * 1976-06-08 1985-07-16 Glaxo Laboratories Limited 2-Formyloxymethyl-clavam
CN1795197B (en) 2003-05-28 2010-06-02 帝斯曼知识产权资产管理有限公司 Cephem compound

Also Published As

Publication number Publication date
AT297932B (en) 1972-04-10
JPS4945594B1 (en) 1974-12-05
SE384690B (en) 1976-05-17
DE2040141B2 (en) 1973-05-03
YU36539B (en) 1984-02-29
FR2068490A1 (en) 1971-08-27
DK128341B (en) 1974-04-16
FI45990C (en) 1972-11-10
GB1315177A (en) 1973-04-26
NL7011805A (en) 1971-02-16
NO132242B (en) 1975-06-30
FR2068490B1 (en) 1974-02-01
CH597347A5 (en) 1978-03-31
FI45990B (en) 1972-07-31
CH602759A5 (en) 1978-07-31
IL35065A0 (en) 1970-10-30
CH594050A5 (en) 1977-12-30
CA954809A (en) 1974-09-17
YU205470A (en) 1982-02-25
ZA705386B (en) 1972-03-29
PL84058B1 (en) 1976-02-28
NO132242C (en) 1975-10-08
CS184309B2 (en) 1978-08-31
OA03599A (en) 1971-03-30
DE2040141A1 (en) 1971-03-04
SE415766B (en) 1980-10-27
PH12529A (en) 1979-05-17
JPS519370B1 (en) 1976-03-26
BE754693A (en) 1971-02-11
CS184312B2 (en) 1978-08-31
ES393985A1 (en) 1975-08-16
DK128017B (en) 1974-02-18
JPS527058B1 (en) 1977-02-26
DE2040141C3 (en) 1973-12-06
BR6915079D0 (en) 1973-03-08
IL35065A (en) 1974-05-16
SU511027A3 (en) 1976-04-15
RO58570A (en) 1975-09-15

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