GB1439668A - Antibiotic bm123 and production thereof - Google Patents
Antibiotic bm123 and production thereofInfo
- Publication number
- GB1439668A GB1439668A GB4253573A GB4253573A GB1439668A GB 1439668 A GB1439668 A GB 1439668A GB 4253573 A GB4253573 A GB 4253573A GB 4253573 A GB4253573 A GB 4253573A GB 1439668 A GB1439668 A GB 1439668A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antibiotic
- infra
- elemental analysis
- absorption spectrum
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
1439668 Antibiotic BM123 AMERICAN CYANAMID CO 10 Sept 1973 [12 Oct 1972] 42535/73 Heading C2A Antibiotic BM123 is prepared by cultivating a microorganism having the characteristics of Nocardia sp. NRRL 5646 or mutants thereof in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions until substantial antibacterial activity is imparted to the medium, and then recovering BM123 therefrom. The antibiotic exists in three forms, designated BM123α, BM123# and BM123#. Antibiotic BM123α is characterized by (a) having an optical rotation (C= 1.00 in water); (b) having the following elemental analysis (per cent); C, 33.89; H, 5.71; N, 11.88; O, 35.40; and (c) the infra-red absorption spectrum indicated in Fig. 1 (not shown). Antibiotic BM123# is characterized by (a) having an optical rotation (C=1.25 in water); (b) having the following elemental analysis: C, 47.53; H, 7.39; N, 16.54; ash, 1.04; and (c) the infra-red absorption spectrum indicated in Fig. 2 (not shown). Antibiotic BM123 # is characterized by (a) having an optical rotation (C= 1.004 in water); (b) having the following elemental analysis: C, 46.13; H, 6.65; N, 17.00; O, 24.96; ash, 0.90; and (c) the infra-red absorption spectrum indicated in Fig. 3 (not shown). These antibiotics may be incorporated with suitable carriers into various pharmaceutical forms.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29717372A | 1972-10-12 | 1972-10-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1439668A true GB1439668A (en) | 1976-06-16 |
Family
ID=23145157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4253573A Expired GB1439668A (en) | 1972-10-12 | 1973-09-10 | Antibiotic bm123 and production thereof |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5434838B2 (en) |
| AR (1) | AR198115A1 (en) |
| BE (1) | BE806029A (en) |
| BG (1) | BG23543A3 (en) |
| CH (1) | CH584287A5 (en) |
| CS (1) | CS191221B2 (en) |
| DD (1) | DD111403A5 (en) |
| DE (1) | DE2351344A1 (en) |
| ES (1) | ES419574A1 (en) |
| FR (1) | FR2202680B1 (en) |
| GB (1) | GB1439668A (en) |
| HK (1) | HK42977A (en) |
| HU (1) | HU166799B (en) |
| IE (1) | IE38136B1 (en) |
| IL (1) | IL43295A (en) |
| NL (1) | NL7314099A (en) |
| PH (1) | PH10065A (en) |
| PL (1) | PL85814B1 (en) |
| RO (1) | RO64690A (en) |
| SE (1) | SE398756B (en) |
| SU (1) | SU618053A3 (en) |
| YU (1) | YU265573A (en) |
| ZA (1) | ZA735897B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1087537A (en) * | 1975-08-21 | 1980-10-14 | John H. E. J. Martin | Antibiotic bm123 and production thereof |
| IL56424A0 (en) * | 1978-02-02 | 1979-03-12 | American Cyanamid Co | Complexes of antibiotic bm123 gamma |
-
1973
- 1973-08-27 IE IE1503/73A patent/IE38136B1/en unknown
- 1973-08-28 ZA ZA735897A patent/ZA735897B/en unknown
- 1973-09-10 GB GB4253573A patent/GB1439668A/en not_active Expired
- 1973-09-14 PH PH15013D patent/PH10065A/en unknown
- 1973-09-19 AR AR250150A patent/AR198115A1/en active
- 1973-09-21 IL IL43295A patent/IL43295A/en unknown
- 1973-09-23 SU SU731968937A patent/SU618053A3/en active
- 1973-10-01 RO RO7300076217A patent/RO64690A/en unknown
- 1973-10-09 BG BG24692A patent/BG23543A3/xx unknown
- 1973-10-10 YU YU02655/73A patent/YU265573A/en unknown
- 1973-10-11 SE SE7313861A patent/SE398756B/en unknown
- 1973-10-11 ES ES419574A patent/ES419574A1/en not_active Expired
- 1973-10-11 DD DD173998A patent/DD111403A5/xx unknown
- 1973-10-11 PL PL1973165781A patent/PL85814B1/pl unknown
- 1973-10-11 CH CH1448673A patent/CH584287A5/xx not_active IP Right Cessation
- 1973-10-12 CS CS737048A patent/CS191221B2/en unknown
- 1973-10-12 JP JP11402473A patent/JPS5434838B2/ja not_active Expired
- 1973-10-12 BE BE136647A patent/BE806029A/en unknown
- 1973-10-12 DE DE19732351344 patent/DE2351344A1/en not_active Withdrawn
- 1973-10-12 HU HUAE395A patent/HU166799B/hu unknown
- 1973-10-12 NL NL7314099A patent/NL7314099A/xx not_active Application Discontinuation
- 1973-10-12 FR FR7336570A patent/FR2202680B1/fr not_active Expired
-
1977
- 1977-08-18 HK HK429/77A patent/HK42977A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5434838B2 (en) | 1979-10-29 |
| SE398756B (en) | 1978-01-16 |
| BG23543A3 (en) | 1977-09-15 |
| DD111403A5 (en) | 1975-02-12 |
| FR2202680B1 (en) | 1976-04-09 |
| BE806029A (en) | 1974-04-12 |
| JPS4975796A (en) | 1974-07-22 |
| PL85814B1 (en) | 1976-04-30 |
| CH584287A5 (en) | 1977-01-31 |
| IE38136L (en) | 1974-04-12 |
| FR2202680A1 (en) | 1974-05-10 |
| ZA735897B (en) | 1974-07-31 |
| IL43295A0 (en) | 1975-08-31 |
| IE38136B1 (en) | 1978-01-04 |
| HU166799B (en) | 1975-06-28 |
| PH10065A (en) | 1976-08-03 |
| IL43295A (en) | 1977-03-31 |
| NL7314099A (en) | 1974-04-16 |
| CS191221B2 (en) | 1979-06-29 |
| YU265573A (en) | 1981-11-13 |
| ES419574A1 (en) | 1976-04-01 |
| AU5995173A (en) | 1975-03-06 |
| AR198115A1 (en) | 1974-05-31 |
| HK42977A (en) | 1977-08-26 |
| DE2351344A1 (en) | 1974-04-25 |
| RO64690A (en) | 1979-01-15 |
| SU618053A3 (en) | 1978-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |