IE38136L - Antibiotic bm 123 - Google Patents
Antibiotic bm 123Info
- Publication number
- IE38136L IE38136L IE731503A IE150373A IE38136L IE 38136 L IE38136 L IE 38136L IE 731503 A IE731503 A IE 731503A IE 150373 A IE150373 A IE 150373A IE 38136 L IE38136 L IE 38136L
- Authority
- IE
- Ireland
- Prior art keywords
- antibiotic
- infra
- elemental analysis
- absorption spectrum
- water
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 7
- 238000000862 absorption spectrum Methods 0.000 abstract 3
- 238000000921 elemental analysis Methods 0.000 abstract 3
- 230000003287 optical effect Effects 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- 241000187681 Nocardia sp. Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
1439668 Antibiotic BM123 AMERICAN CYANAMID CO 10 Sept 1973 [12 Oct 1972] 42535/73 Heading C2A Antibiotic BM123 is prepared by cultivating a microorganism having the characteristics of Nocardia sp. NRRL 5646 or mutants thereof in an aqueous nutrient medium containing assimilable sources of carbon, nitrogen and inorganic salts under submerged aerobic conditions until substantial antibacterial activity is imparted to the medium, and then recovering BM123 therefrom. The antibiotic exists in three forms, designated BM123α, BM123# and BM123#. Antibiotic BM123α is characterized by (a) having an optical rotation (C= 1.00 in water); (b) having the following elemental analysis (per cent); C, 33.89; H, 5.71; N, 11.88; O, 35.40; and (c) the infra-red absorption spectrum indicated in Fig. 1 (not shown). Antibiotic BM123# is characterized by (a) having an optical rotation (C=1.25 in water); (b) having the following elemental analysis: C, 47.53; H, 7.39; N, 16.54; ash, 1.04; and (c) the infra-red absorption spectrum indicated in Fig. 2 (not shown). Antibiotic BM123 # is characterized by (a) having an optical rotation (C= 1.004 in water); (b) having the following elemental analysis: C, 46.13; H, 6.65; N, 17.00; O, 24.96; ash, 0.90; and (c) the infra-red absorption spectrum indicated in Fig. 3 (not shown). These antibiotics may be incorporated with suitable carriers into various pharmaceutical forms.
[GB1439668A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29717372A | 1972-10-12 | 1972-10-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38136L true IE38136L (en) | 1974-04-12 |
| IE38136B1 IE38136B1 (en) | 1978-01-04 |
Family
ID=23145157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1503/73A IE38136B1 (en) | 1972-10-12 | 1973-08-27 | Antibiotic bm123 and production thereof |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5434838B2 (en) |
| AR (1) | AR198115A1 (en) |
| BE (1) | BE806029A (en) |
| BG (1) | BG23543A3 (en) |
| CH (1) | CH584287A5 (en) |
| CS (1) | CS191221B2 (en) |
| DD (1) | DD111403A5 (en) |
| DE (1) | DE2351344A1 (en) |
| ES (1) | ES419574A1 (en) |
| FR (1) | FR2202680B1 (en) |
| GB (1) | GB1439668A (en) |
| HK (1) | HK42977A (en) |
| HU (1) | HU166799B (en) |
| IE (1) | IE38136B1 (en) |
| IL (1) | IL43295A (en) |
| NL (1) | NL7314099A (en) |
| PH (1) | PH10065A (en) |
| PL (1) | PL85814B1 (en) |
| RO (1) | RO64690A (en) |
| SE (1) | SE398756B (en) |
| SU (1) | SU618053A3 (en) |
| YU (1) | YU265573A (en) |
| ZA (1) | ZA735897B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1087537A (en) * | 1975-08-21 | 1980-10-14 | John H. E. J. Martin | Antibiotic bm123 and production thereof |
| IL56424A0 (en) * | 1978-02-02 | 1979-03-12 | American Cyanamid Co | Complexes of antibiotic bm123 gamma |
-
1973
- 1973-08-27 IE IE1503/73A patent/IE38136B1/en unknown
- 1973-08-28 ZA ZA735897A patent/ZA735897B/en unknown
- 1973-09-10 GB GB4253573A patent/GB1439668A/en not_active Expired
- 1973-09-14 PH PH15013D patent/PH10065A/en unknown
- 1973-09-19 AR AR250150A patent/AR198115A1/en active
- 1973-09-21 IL IL43295A patent/IL43295A/en unknown
- 1973-09-23 SU SU731968937A patent/SU618053A3/en active
- 1973-10-01 RO RO7300076217A patent/RO64690A/en unknown
- 1973-10-09 BG BG024692A patent/BG23543A3/en unknown
- 1973-10-10 YU YU02655/73A patent/YU265573A/en unknown
- 1973-10-11 SE SE7313861A patent/SE398756B/en unknown
- 1973-10-11 CH CH1448673A patent/CH584287A5/xx not_active IP Right Cessation
- 1973-10-11 DD DD173998A patent/DD111403A5/xx unknown
- 1973-10-11 PL PL1973165781A patent/PL85814B1/pl unknown
- 1973-10-11 ES ES419574A patent/ES419574A1/en not_active Expired
- 1973-10-12 BE BE136647A patent/BE806029A/en unknown
- 1973-10-12 CS CS737048A patent/CS191221B2/en unknown
- 1973-10-12 DE DE19732351344 patent/DE2351344A1/en not_active Withdrawn
- 1973-10-12 FR FR7336570A patent/FR2202680B1/fr not_active Expired
- 1973-10-12 HU HUAE395A patent/HU166799B/hu unknown
- 1973-10-12 JP JP11402473A patent/JPS5434838B2/ja not_active Expired
- 1973-10-12 NL NL7314099A patent/NL7314099A/xx not_active Application Discontinuation
-
1977
- 1977-08-18 HK HK429/77A patent/HK42977A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2202680B1 (en) | 1976-04-09 |
| SE398756B (en) | 1978-01-16 |
| FR2202680A1 (en) | 1974-05-10 |
| ES419574A1 (en) | 1976-04-01 |
| PL85814B1 (en) | 1976-04-30 |
| GB1439668A (en) | 1976-06-16 |
| RO64690A (en) | 1979-01-15 |
| ZA735897B (en) | 1974-07-31 |
| IL43295A0 (en) | 1975-08-31 |
| YU265573A (en) | 1981-11-13 |
| PH10065A (en) | 1976-08-03 |
| JPS5434838B2 (en) | 1979-10-29 |
| AR198115A1 (en) | 1974-05-31 |
| HU166799B (en) | 1975-06-28 |
| JPS4975796A (en) | 1974-07-22 |
| CH584287A5 (en) | 1977-01-31 |
| IE38136B1 (en) | 1978-01-04 |
| CS191221B2 (en) | 1979-06-29 |
| DE2351344A1 (en) | 1974-04-25 |
| HK42977A (en) | 1977-08-26 |
| AU5995173A (en) | 1975-03-06 |
| IL43295A (en) | 1977-03-31 |
| SU618053A3 (en) | 1978-07-30 |
| DD111403A5 (en) | 1975-02-12 |
| BE806029A (en) | 1974-04-12 |
| NL7314099A (en) | 1974-04-16 |
| BG23543A3 (en) | 1977-09-15 |
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