GB1377339A - Method for producing deacetoxycephalosporin c - Google Patents

Method for producing deacetoxycephalosporin c

Info

Publication number
GB1377339A
GB1377339A GB1838773A GB1838773A GB1377339A GB 1377339 A GB1377339 A GB 1377339A GB 1838773 A GB1838773 A GB 1838773A GB 1838773 A GB1838773 A GB 1838773A GB 1377339 A GB1377339 A GB 1377339A
Authority
GB
United Kingdom
Prior art keywords
nrrl
desacetoxycephalosporin
april
cephalosporium
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1838773A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00348341A external-priority patent/US3847742A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of GB1377339A publication Critical patent/GB1377339A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

1377339 Producing desacetoxycephalosporin C ELI LILLY & CO 17 April 1973 [26 April 1972 (4) 9 April 1973] 18387/73 Heading C2C Desacetoxycephalosporin C is produced by aerobically cultivating a desacetoxycephalosporin C- and penicillin N-CO-producing micro-organism of the genus Cephalosporium, Emeicellopsis, Scopulariopsis, Paecilomyces or Diheterospora in aqueous nutrient medium and then isolating desacetoxycephalosporin C from the resulting culture medium. The preferred organisms are Cephalosporium chrysogenum ATCC 14615, Cephalosporium sp. NRRL 5445, 5446, 5447, 5712, 5716, 5718, 5719, 5720, 5721, 5722, 5723, 5724 and 5725; Emericellopsis sp. NRRL 5446, 5447, 5713, 5714 and 5717; Scopulariopsis sp. NRRL 5715; Paecilomyces carneus NRRL 5711; and Diheterospora chlamydosporia NRRL 5728. The product is isolated by acidifying the whole culture broth to about pH 2, filtering off the mycelium and adsorbing the product on carbon followed by elution with aqueous acetone.
GB1838773A 1972-04-26 1973-04-17 Method for producing deacetoxycephalosporin c Expired GB1377339A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24766972A 1972-04-26 1972-04-26
US24760872A 1972-04-26 1972-04-26
US24766772A 1972-04-26 1972-04-26
US24766872A 1972-04-26 1972-04-26
US00348341A US3847742A (en) 1972-04-26 1973-04-09 Process for deacetoxycephalosporin c

Publications (1)

Publication Number Publication Date
GB1377339A true GB1377339A (en) 1974-12-11

Family

ID=27540254

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1838773A Expired GB1377339A (en) 1972-04-26 1973-04-17 Method for producing deacetoxycephalosporin c

Country Status (17)

Country Link
JP (1) JPS5752840B2 (en)
AR (1) AR197502A1 (en)
AU (1) AU472455B2 (en)
CA (1) CA985648A (en)
CH (1) CH565246A5 (en)
DD (1) DD103261A5 (en)
DE (1) DE2320696A1 (en)
DK (1) DK135326B (en)
FR (1) FR2182136B1 (en)
GB (1) GB1377339A (en)
IE (1) IE37561B1 (en)
IL (1) IL42050A (en)
NL (1) NL7305881A (en)
PH (1) PH13200A (en)
RO (1) RO63439A (en)
SE (1) SE388873B (en)
SU (1) SU582772A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234093A (en) * 2021-04-13 2021-08-10 伊犁川宁生物技术股份有限公司 3-deacetoxy cephalosporin C sodium salt and preparation method thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5417031B2 (en) * 1973-06-16 1979-06-27
JPS5421437B2 (en) * 1973-10-08 1979-07-30

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113234093A (en) * 2021-04-13 2021-08-10 伊犁川宁生物技术股份有限公司 3-deacetoxy cephalosporin C sodium salt and preparation method thereof

Also Published As

Publication number Publication date
IE37561L (en) 1973-10-26
PH13200A (en) 1980-01-28
AU472455B2 (en) 1976-05-27
DE2320696A1 (en) 1973-11-15
RO63439A (en) 1978-08-15
AR197502A1 (en) 1974-04-15
FR2182136A1 (en) 1973-12-07
FR2182136B1 (en) 1975-08-22
NL7305881A (en) 1973-10-30
AU5468873A (en) 1974-10-24
SU582772A3 (en) 1977-11-30
DK135326C (en) 1977-09-19
JPS4947595A (en) 1974-05-08
SE388873B (en) 1976-10-18
JPS5752840B2 (en) 1982-11-10
CH565246A5 (en) 1975-08-15
DD103261A5 (en) 1974-01-12
IL42050A (en) 1976-08-31
IE37561B1 (en) 1977-08-17
DK135326B (en) 1977-04-04
CA985648A (en) 1976-03-16

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee