KR840005151A - 세팔로스포린 항생물질의 제조방법 - Google Patents

세팔로스포린 항생물질의 제조방법 Download PDF

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Publication number
KR840005151A
KR840005151A KR1019830002945A KR830002945A KR840005151A KR 840005151 A KR840005151 A KR 840005151A KR 1019830002945 A KR1019830002945 A KR 1019830002945A KR 830002945 A KR830002945 A KR 830002945A KR 840005151 A KR840005151 A KR 840005151A
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KR
South Korea
Prior art keywords
compound
group
formula
salt
toxic
Prior art date
Application number
KR1019830002945A
Other languages
English (en)
Korean (ko)
Inventor
에드가 루커 브리안
Original Assignee
배리 안토니 뉴삼
글락소 그룹 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 배리 안토니 뉴삼, 글락소 그룹 리미티드 filed Critical 배리 안토니 뉴삼
Publication of KR840005151A publication Critical patent/KR840005151A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019830002945A 1982-06-30 1983-06-29 세팔로스포린 항생물질의 제조방법 KR840005151A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8218874 1982-06-30
GB8218874 1982-06-30

Publications (1)

Publication Number Publication Date
KR840005151A true KR840005151A (ko) 1984-11-03

Family

ID=10531380

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019830002946A KR840005150A (ko) 1982-06-30 1983-06-29 세팔로스포린 항생물질의 제조방법
KR1019830002945A KR840005151A (ko) 1982-06-30 1983-06-29 세팔로스포린 항생물질의 제조방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019830002946A KR840005150A (ko) 1982-06-30 1983-06-29 세팔로스포린 항생물질의 제조방법

Country Status (19)

Country Link
JP (3) JPS5913787A (ja)
KR (2) KR840005150A (ja)
AU (1) AU1638083A (ja)
BE (2) BE897162A (ja)
DE (1) DE3323450A1 (ja)
DK (1) DK298983A (ja)
ES (2) ES8500956A1 (ja)
FI (1) FI832384L (ja)
FR (2) FR2529556A1 (ja)
GB (1) GB2123415A (ja)
GR (1) GR77528B (ja)
IT (1) IT1173727B (ja)
LU (1) LU84886A1 (ja)
NL (1) NL8302308A (ja)
NO (1) NO832375L (ja)
PL (2) PL249795A1 (ja)
PT (1) PT76959B (ja)
SE (1) SE8303728D0 (ja)
ZA (3) ZA834757B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001833A1 (en) * 1990-07-18 1992-02-06 Peter John Mitchell Farley Process and apparatus for the production of paper products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS54157519A (en) * 1978-06-01 1979-12-12 Mitsubishi Gas Chem Co Inc Preparation of dimethylformamide
DE2940407A1 (de) * 1979-10-05 1981-04-09 Cornelius Apparate Gmbh, 4018 Langenfeld Verfahren und vorrichtung zur anreicherung von fluessigkeiten mit gasen

Also Published As

Publication number Publication date
ES523681A0 (es) 1984-11-01
FI832384A0 (fi) 1983-06-29
ES8500956A1 (es) 1984-11-01
FR2543949A1 (fr) 1984-10-12
JPS5913787A (ja) 1984-01-24
ZA834757B (en) 1984-04-25
ZA834759B (en) 1984-08-29
ZA834758B (en) 1984-04-25
ES8602019A1 (es) 1985-11-01
DK298983D0 (da) 1983-06-29
SE8303728L (ja) 1984-12-30
LU84886A1 (fr) 1984-03-07
NO832375L (no) 1984-01-02
GB2123415A (en) 1984-02-01
PL242747A1 (en) 1985-01-30
PL249795A1 (en) 1985-06-04
GR77528B (ja) 1984-09-24
SE8303728D0 (sv) 1983-06-29
NL8302308A (nl) 1984-01-16
JPS5913786A (ja) 1984-01-24
IT8348599A0 (it) 1983-06-29
ES530071A0 (es) 1985-11-01
AU1638083A (en) 1984-01-05
KR840005150A (ko) 1984-11-03
PT76959B (en) 1986-01-24
PT76959A (en) 1983-07-01
DK298983A (da) 1983-12-31
FI832384L (fi) 1983-12-31
GB8317618D0 (en) 1983-08-03
IT1173727B (it) 1987-06-24
DE3323450A1 (de) 1984-01-12
JPS5913788A (ja) 1984-01-24
FR2529556A1 (fr) 1984-01-06
BE897162A (fr) 1983-12-29
BE897163A (fr) 1983-12-29

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