ES8402592A1 - Procedimiento para la obtencion de compuestos de acido 7b-aminooxazolilacetilamino-3-cefem-4-carboxilico. - Google Patents
Procedimiento para la obtencion de compuestos de acido 7b-aminooxazolilacetilamino-3-cefem-4-carboxilico.Info
- Publication number
- ES8402592A1 ES8402592A1 ES516013A ES516013A ES8402592A1 ES 8402592 A1 ES8402592 A1 ES 8402592A1 ES 516013 A ES516013 A ES 516013A ES 516013 A ES516013 A ES 516013A ES 8402592 A1 ES8402592 A1 ES 8402592A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- formula
- pharmaceutical compositions
- compositions containing
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE ACIDO 7BBB-AMINOOXAZOLILACETILAMINO-3-CEFEM-4-CARBOXIL ICO.CONSISTE EN LA ACILACION EN UN MEDIO ANHIDRO, EN PRESENCIA DE UN DISOLVENTE COMO CLORURO METILENICO, ETC., Y CON TEMPERATURAS ENTRE C40J Y 100JC; DE UN COMPUESTO DE FORMULA (II) POR MEDIO DE UN COMPUESTO DE FORMULA (III) PARA OBTENER COMPUESTOS DE FORMULA (I), DONDE R1 SIGNIFICA HIDROGENO, ALQUILO INFERIOR; N VARIA DE 0 A 2; R3 SIGNIFICA CARBOXILO, ETC.; 7BBB-AMINO VA PROTEGIDO Y LIBRE; A SIGNIFICA CARBONILO, O GRUPO METILENO SUSTITUIDO POR AMINO PROTEGIDO O POR UN GRUPO DEFORMULA FN-O-R4; DONDE R4 SIGNIFICA HIDROGENO, ALQUILO INFERIOR, ALQUILO INFERIOR SUSTITUIDO, CIDOALQUILO Y OTROS.TIENE APLICACIONES EN LA PREOBTENCION DE PRODUCTOS FARMACEUTICOS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH630381 | 1981-09-30 | ||
CH304982 | 1982-05-17 | ||
CH480782 | 1982-08-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES516013A0 ES516013A0 (es) | 1984-02-01 |
ES8402592A1 true ES8402592A1 (es) | 1984-02-01 |
Family
ID=27174099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES516013A Expired ES8402592A1 (es) | 1981-09-30 | 1982-09-28 | Procedimiento para la obtencion de compuestos de acido 7b-aminooxazolilacetilamino-3-cefem-4-carboxilico. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0076452A3 (es) |
DD (1) | DD204256A5 (es) |
DK (1) | DK432582A (es) |
ES (1) | ES8402592A1 (es) |
FI (1) | FI823304L (es) |
GB (1) | GB2106519B (es) |
GR (1) | GR77677B (es) |
MA (1) | MA19602A1 (es) |
NO (1) | NO823291L (es) |
PT (1) | PT75626B (es) |
RO (1) | RO84457B (es) |
ZW (1) | ZW20982A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0096297B1 (de) * | 1982-06-03 | 1988-06-15 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von 1-Sulfo-2-oxoazetidinderivaten |
JPS6197288A (ja) * | 1984-10-19 | 1986-05-15 | Kaken Pharmaceut Co Ltd | セフアロスポリン化合物 |
US4698338A (en) * | 1986-02-19 | 1987-10-06 | Eli Lilly And Company | 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins |
HUT53892A (en) * | 1989-04-07 | 1990-12-28 | Technologishen Kom Za Promy Mi | Process for producing synaminothiazolyl and synaminooxazolyl derivatives |
US20110118462A1 (en) * | 2009-11-18 | 2011-05-19 | Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory | N-heterocyclic substituent-containing antibiotic, preparation and use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH557381A (de) * | 1967-04-15 | 1974-12-31 | Fujisawa Pharmaceutical Co | Verfahren zur herstellung von (delta)3-cephemverbindungen. |
FR2068419A1 (en) * | 1969-10-27 | 1971-08-27 | Fujisawa Pharmaceutical Co | Antibacterial cephalosporin compsns |
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
CA1088049A (en) * | 1975-06-03 | 1980-10-21 | Takashi Masugi | 3-substituted-7-substituted alkanamido-3-cephem-4- carboxylic acid compounds and processes for preparation thereof |
US4430499A (en) * | 1981-09-08 | 1984-02-07 | Eli Lilly And Company | 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido]cephalosporin antibiotics |
US4382932A (en) * | 1981-09-08 | 1983-05-10 | Eli Lilly And Company | Isoquinolinium substituted cephalosporins |
US4382931A (en) * | 1981-09-08 | 1983-05-10 | Eli Lilly And Company | 3'-Substituted quinolinium cephalosporins |
US4388316A (en) * | 1981-10-02 | 1983-06-14 | Eli Lilly And Company | Amino-substituted oxazole, oxadiazole and isoxazole-substituted cephalosporins |
US4379787A (en) * | 1981-10-02 | 1983-04-12 | Eli Lilly And Company | Oximino-substituted cephalosporin compounds |
EP0096297B1 (de) * | 1982-06-03 | 1988-06-15 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von 1-Sulfo-2-oxoazetidinderivaten |
-
1982
- 1982-09-22 MA MA19814A patent/MA19602A1/fr unknown
- 1982-09-27 FI FI823304A patent/FI823304L/fi not_active Application Discontinuation
- 1982-09-27 EP EP82108930A patent/EP0076452A3/de not_active Withdrawn
- 1982-09-28 GR GR69375A patent/GR77677B/el unknown
- 1982-09-28 DD DD82243550A patent/DD204256A5/de unknown
- 1982-09-28 ZW ZW209/82A patent/ZW20982A1/xx unknown
- 1982-09-28 ES ES516013A patent/ES8402592A1/es not_active Expired
- 1982-09-29 DK DK432582A patent/DK432582A/da not_active Application Discontinuation
- 1982-09-29 RO RO108712A patent/RO84457B/ro unknown
- 1982-09-29 PT PT75626A patent/PT75626B/pt unknown
- 1982-09-29 GB GB08227774A patent/GB2106519B/en not_active Expired
- 1982-09-29 NO NO823291A patent/NO823291L/no unknown
Also Published As
Publication number | Publication date |
---|---|
PT75626B (de) | 1985-12-09 |
FI823304L (fi) | 1983-03-31 |
DK432582A (da) | 1983-03-31 |
EP0076452A3 (de) | 1984-09-05 |
RO84457A (ro) | 1984-06-21 |
MA19602A1 (fr) | 1983-04-01 |
GB2106519B (en) | 1985-04-24 |
EP0076452A2 (de) | 1983-04-13 |
RO84457B (ro) | 1984-08-30 |
FI823304A0 (fi) | 1982-09-27 |
GR77677B (es) | 1984-09-25 |
NO823291L (no) | 1983-04-05 |
ZW20982A1 (en) | 1983-04-27 |
PT75626A (de) | 1982-10-01 |
GB2106519A (en) | 1983-04-13 |
DD204256A5 (de) | 1983-11-23 |
ES516013A0 (es) | 1984-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES443627A1 (es) | Un procedimiento para preparar un compuesto de cefem. | |
JPS5756485A (en) | Cephem of penam compound and its preparation | |
JPS5686188A (en) | 7-acylamino-3-substituted cephalosporanic acid derivative and its preparation | |
ES483986A1 (es) | Procedimiento para la obtencion de compuestos del acido 7b- aminotiazolil acetamido-3-cefem-4-carboxilico | |
FI864825A (fi) | Cefalosporinderivat. | |
IL57392A0 (en) | Novel cephalosporin derivatives their preparation and pharmaceutical compositions containing them | |
JPS5798288A (en) | Novel cephem compound or its salt, their preparation, and preventive and remedy for bacteriosis containing said compound as active component | |
ES8402592A1 (es) | Procedimiento para la obtencion de compuestos de acido 7b-aminooxazolilacetilamino-3-cefem-4-carboxilico. | |
JPS6485A (en) | Novel cephalosporin derivative | |
ES480762A1 (es) | Procedimiento para la preparacion de derivados de cefem. | |
JPS5643288A (en) | Cephalosporin derivative and its preparation | |
JPS5799592A (en) | Novel cephalosporins | |
DE3375787D1 (en) | Cephalosporin derivatives, methods of production thereof and prophylactic and therapeutic agents for bacterial infection | |
ES8202828A1 (es) | Procedimiento para la obtencion de compuestos de isotiazoli-lo | |
ES8504818A1 (es) | Procedimiento para la obtencion de compuestos del acido 7-acilamido-3-cefem-4-carboxilico. | |
ES8307822A1 (es) | Procedimiento para la obtencion de acido 7b-acilamido-3-cefem-4-carboxilico. | |
ES8305773A1 (es) | Procedimiento para la obtencion de compuestos de aminohidroxifenilo. | |
ES8401081A1 (es) | Procedimiento para la obtencion de compuestos del acido 7b-aminotriazolilacetilamino-3-cefem-4-carboxilico. | |
HUT42492A (en) | Process for producing cepheme-carboxylic acid derivatives and pharmaceutical compositions containing them as active agents | |
ES8701181A1 (es) | Procedimiento para la obtencion de compuestos del acido 7b - acilamido-3-cefem-4-carboxilico | |
JPS5547690A (en) | Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituents | |
JPS5646883A (en) | Novel cephalosporin compound and its preparation | |
ES8302721A1 (es) | Un procedimiento para la preparacion de derivados de cefa- losporina | |
JPS57167993A (en) | Novel 3-((4-carboxy-3-hydroxyisothiazole-5-yl) thiomethyl)-delta3-cephem derivative | |
ES8401491A1 (es) | Procedimiento para la obtencion de compuestos de 2-aminobutil-6-hidroximetil-2-penem. |