ES483986A1 - Procedimiento para la obtencion de compuestos del acido 7b- aminotiazolil acetamido-3-cefem-4-carboxilico - Google Patents

Procedimiento para la obtencion de compuestos del acido 7b- aminotiazolil acetamido-3-cefem-4-carboxilico

Info

Publication number
ES483986A1
ES483986A1 ES483986A ES483986A ES483986A1 ES 483986 A1 ES483986 A1 ES 483986A1 ES 483986 A ES483986 A ES 483986A ES 483986 A ES483986 A ES 483986A ES 483986 A1 ES483986 A1 ES 483986A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
optionally protected
compounds
preparation
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES483986A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES483986A1 publication Critical patent/ES483986A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Procedimiento para la obtención de compuestos del ácido 7beta- aminatiazolil-acetamido-3-cefem-4-carboxílico de fórmula **(Fórmula)** donde R1 significa hidrógeno, alquilo inferior o un grupo amino protector, A significa metileno o metileno, en caso dado sustituido por amino, en caso dado protegido, hidroxi, sulfo, en caso dado protegido, oxo, hidroxiimino, en caso dado protegido o metoxiimino, R2 significa hidrógeno o un resto esterificador del grupo carboxilo, y R3 significa un resto heterociclilo, y las sales de tales compuestos con grupos formadores de sal.
ES483986A 1978-09-08 1979-09-07 Procedimiento para la obtencion de compuestos del acido 7b- aminotiazolil acetamido-3-cefem-4-carboxilico Expired ES483986A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH946878 1978-09-08

Publications (1)

Publication Number Publication Date
ES483986A1 true ES483986A1 (es) 1980-04-16

Family

ID=4352310

Family Applications (1)

Application Number Title Priority Date Filing Date
ES483986A Expired ES483986A1 (es) 1978-09-08 1979-09-07 Procedimiento para la obtencion de compuestos del acido 7b- aminotiazolil acetamido-3-cefem-4-carboxilico

Country Status (5)

Country Link
EP (1) EP0009008A3 (es)
JP (1) JPS5538392A (es)
DK (1) DK374679A (es)
ES (1) ES483986A1 (es)
ZA (1) ZA794749B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
JPS5838289A (ja) * 1981-08-29 1983-03-05 Meiji Seika Kaisha Ltd 化学的方法の改良法
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
FR2550200B1 (fr) * 1983-08-01 1988-04-08 Fujisawa Pharmaceutical Co Procede de preparation de composes de cephem a activite antimicrobienne et nouveaux produits ainsi obtenus
US5332731A (en) * 1989-12-07 1994-07-26 Meiji Seika Kaisha, Ltd. Cephalosporin derivatives
IL100576A (en) * 1991-01-18 1995-11-27 Eli Lilley And Company Cephalosporin antibiotics
JPH05132488A (ja) * 1991-08-13 1993-05-28 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体
JP2857532B2 (ja) * 1992-03-12 1999-02-17 明治製菓株式会社 新規セファロスポリン誘導体
TW427993B (en) * 1993-09-09 2001-04-01 Fujisawa Pharmaceutical Co New cephem compounds
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
CZ287296A3 (en) * 1994-04-01 1997-05-14 Microcide Pharmaceuticals Cephalosporin antibiotics and antibacterial preparations in which they are comprised
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
WO1996017850A1 (en) * 1994-12-09 1996-06-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and pharmaceutical use thereof
JP2845789B2 (ja) * 1995-12-25 1999-01-13 株式会社トクヤマ アミノチアゾール酢酸誘導体の製造方法
AUPN801196A0 (en) * 1996-02-12 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and pharmaceutical use thereof
US6545004B1 (en) 1999-10-27 2003-04-08 Cytokinetics, Inc. Methods and compositions utilizing quinazolinones
US6599893B2 (en) * 2000-08-29 2003-07-29 Essential Therapeutics, Inc. Cephalosporin antibiotics and prodrugs thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605997A5 (es) * 1974-08-30 1978-10-13 Ciba Geigy Ag
JPS53103493A (en) * 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
JPS5538392A (en) 1980-03-17
EP0009008A2 (de) 1980-03-19
EP0009008A3 (de) 1980-05-14
ZA794749B (en) 1980-08-27
DK374679A (da) 1980-03-09

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