CH605997A5 - - Google Patents

Info

Publication number
CH605997A5
CH605997A5 CH1183674A CH1183674A CH605997A5 CH 605997 A5 CH605997 A5 CH 605997A5 CH 1183674 A CH1183674 A CH 1183674A CH 1183674 A CH1183674 A CH 1183674A CH 605997 A5 CH605997 A5 CH 605997A5
Authority
CH
Switzerland
Application number
CH1183674A
Inventor
Robert Burns Prof Dr Woodward
Hans Dr Bickel
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH1183674A priority Critical patent/CH605997A5/xx
Priority to DE19752537974 priority patent/DE2537974A1/de
Priority to GB35214/75A priority patent/GB1516655A/en
Priority to NL7510072A priority patent/NL7510072A/xx
Priority to US05/607,983 priority patent/US4256739A/en
Priority to GB51147/77A priority patent/GB1516656A/en
Priority to FR7526508A priority patent/FR2282895A1/fr
Priority to JP50105559A priority patent/JPS5148690A/ja
Publication of CH605997A5 publication Critical patent/CH605997A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1183674A 1974-08-30 1974-08-30 CH605997A5 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CH1183674A CH605997A5 (es) 1974-08-30 1974-08-30
DE19752537974 DE2537974A1 (de) 1974-08-30 1975-08-26 Thioderivate
GB35214/75A GB1516655A (en) 1974-08-30 1975-08-26 3-substituted thio-cephem-4-carboxylic acid derivatives
NL7510072A NL7510072A (nl) 1974-08-30 1975-08-26 Werkwijze ter bereiding van thioderivaten.
US05/607,983 US4256739A (en) 1974-08-30 1975-08-26 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them
GB51147/77A GB1516656A (en) 1974-08-30 1975-08-26 3-sulphonyloxy-cephem-4-carboxylic acid derivatives
FR7526508A FR2282895A1 (fr) 1974-08-30 1975-08-28 Derives d'acides thio-cephem-carboxyliques utiles comme medicaments et leur procede de preparation
JP50105559A JPS5148690A (en) 1974-08-30 1975-08-29 7 beeta amino 33 chioosefuemu 44 karubonsankagobutsu mataha sotosurusefuamukagobutsunoseiho

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1183674A CH605997A5 (es) 1974-08-30 1974-08-30

Publications (1)

Publication Number Publication Date
CH605997A5 true CH605997A5 (es) 1978-10-13

Family

ID=4377375

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1183674A CH605997A5 (es) 1974-08-30 1974-08-30

Country Status (7)

Country Link
US (1) US4256739A (es)
JP (1) JPS5148690A (es)
CH (1) CH605997A5 (es)
DE (1) DE2537974A1 (es)
FR (1) FR2282895A1 (es)
GB (2) GB1516656A (es)
NL (1) NL7510072A (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
US4150156A (en) * 1975-11-21 1979-04-17 Merck & Co., Inc. 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
GB1565941A (en) 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
EP0009008A3 (de) * 1978-09-08 1980-05-14 Ciba-Geigy Ag Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
US4739048A (en) * 1980-05-29 1988-04-19 Merck & Co., Inc. Process for the preparation of thienamycin and intermediates
NZ198350A (en) * 1980-09-25 1985-02-28 Toyama Chemical Co Ltd Cephalosporins and intermediates;pharmaceutical compositions
US4745188A (en) * 1980-11-21 1988-05-17 Merck & Co., Inc. Process for preparing 3-substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
GR76342B (es) * 1981-02-02 1984-08-06 Fujisawa Pharmaceutical Co
JPS5984890A (ja) 1982-11-05 1984-05-16 Hisayasu Ishimaru 経口用セフアロスポリン化合物
FR2550200B1 (fr) * 1983-08-01 1988-04-08 Fujisawa Pharmaceutical Co Procede de preparation de composes de cephem a activite antimicrobienne et nouveaux produits ainsi obtenus
GB8329030D0 (en) * 1983-10-31 1983-11-30 Fujisawa Pharmaceutical Co Cephem compounds
JPH0653739B2 (ja) * 1984-11-15 1994-07-20 協和醗酵工業株式会社 ３位置換カルバセフエム化合物
JPS6242989A (ja) * 1986-08-04 1987-02-24 Sumitomo Pharmaceut Co Ltd 溶接電極の自動整形および交換装置
JPH0686459B2 (ja) * 1989-12-07 1994-11-02 明治製菓株式会社 ３―置換チオ―３―セフエム化合物の製造法
EP0432042B1 (en) * 1989-12-07 1996-08-28 Meiji Seika Kaisha Ltd. Cephalosporin derivatives and their production and uses
JP2857532B2 (ja) * 1992-03-12 1999-02-17 明治製菓株式会社 新規セファロスポリン誘導体
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
WO1995026966A1 (en) * 1994-04-01 1995-10-12 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
WO1996017850A1 (en) * 1994-12-09 1996-06-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and pharmaceutical use thereof
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
AUPN801196A0 (en) * 1996-02-12 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds and pharmaceutical use thereof
US6025352A (en) * 1997-09-29 2000-02-15 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6030965A (en) * 1997-09-30 2000-02-29 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
JP4535530B2 (ja) * 1999-09-20 2010-09-01 大塚化学株式会社 ３−スルホニルオキシ−３−セフェム化合物の製造方法
EP1444237A1 (en) * 2001-11-12 2004-08-11 Hans Rudolf Pfaendler Novel c-3 s/o- and s/n formaldehe acetal derivatives of cephalo sporins and their use as antibiotics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1012943A (en) * 1961-05-16 1965-12-15 Glaxo Lab Ltd Improvements in or relating to antibiotics
US3766177A (en) * 1970-08-17 1973-10-16 Lilly Co Eli Certain delta-3 cephalosporin compounds
US3917587A (en) * 1972-11-28 1975-11-04 Lilly Co Eli Cephalosporin ethers
US3917588A (en) * 1972-11-28 1975-11-04 Lilly Co Eli {60 -Aminoacyl cephalosporin ethers
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
US3992377A (en) * 1974-12-13 1976-11-16 Eli Lilly And Company 3-Thio-substituted cephalosporin antibiotics
JPS5214789A (en) * 1975-07-22 1977-02-03 Shionogi & Co Ltd Process for preparing 3-substiuted cephem compounds by ring closure
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
US4150156A (en) * 1975-11-21 1979-04-17 Merck & Co., Inc. 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE2537974A1 (de) 1976-03-11
NL7510072A (nl) 1976-03-02
GB1516655A (en) 1978-07-05
US4256739A (en) 1981-03-17
FR2282895A1 (fr) 1976-03-26
FR2282895B1 (es) 1980-03-21
JPS5148690A (en) 1976-04-26
GB1516656A (en) 1978-07-05

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Legal Events

Date Code Title Description
PL Patent ceased