KR840002014B1 - 약학적 제제의 제조방법 - Google Patents

약학적 제제의 제조방법 Download PDF

Info

Publication number
KR840002014B1
KR840002014B1 KR1019810000962A KR810000962A KR840002014B1 KR 840002014 B1 KR840002014 B1 KR 840002014B1 KR 1019810000962 A KR1019810000962 A KR 1019810000962A KR 810000962 A KR810000962 A KR 810000962A KR 840002014 B1 KR840002014 B1 KR 840002014B1
Authority
KR
South Korea
Prior art keywords
solution
water
diamino
sulfonamide
enhancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019810000962A
Other languages
English (en)
Korean (ko)
Other versions
KR830004845A (ko
Inventor
이반콤피스
Original Assignee
에프, 호프만-라 롯슈 앤드 캄파니 아크티엔 게젤
쿠르트 네셀보쉬, 한스 스튀클린 샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에프, 호프만-라 롯슈 앤드 캄파니 아크티엔 게젤, 쿠르트 네셀보쉬, 한스 스튀클린 샤프트 filed Critical 에프, 호프만-라 롯슈 앤드 캄파니 아크티엔 게젤
Publication of KR830004845A publication Critical patent/KR830004845A/ko
Application granted granted Critical
Publication of KR840002014B1 publication Critical patent/KR840002014B1/ko
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019810000962A 1980-03-25 1981-03-24 약학적 제제의 제조방법 Expired KR840002014B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH2328/80A CH647412A5 (de) 1980-03-25 1980-03-25 Pharmazeutische praeparate.
CH2328/80 1980-03-25

Publications (2)

Publication Number Publication Date
KR830004845A KR830004845A (ko) 1983-07-20
KR840002014B1 true KR840002014B1 (ko) 1984-11-05

Family

ID=4231246

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810000962A Expired KR840002014B1 (ko) 1980-03-25 1981-03-24 약학적 제제의 제조방법

Country Status (46)

Country Link
US (1) US4532245A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0037501B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS56145224A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR840002014B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR231230A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) ATE8460T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU545277B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (1) BG35324A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR8101752A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1158158A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH647412A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS235086B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CU (1) CU35438A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD157536A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3164826D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK158829C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DZ (1) DZ276A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES500635A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI72876C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2479211A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2073587B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR74453B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK78184A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU185415B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE51065B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL62432A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN152637B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IS (1) IS2626A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1210991B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KE (1) KE3419A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU83246A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MC (1) MC1372A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MT (1) MTP884B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MW (1) MW881A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8500681A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL8101152A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO158656C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ196553A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (1) OA06776A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH17972A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT72727B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO82024B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE8101884L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SG (1) SG43384G (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA811843B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZW (1) ZW4881A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0075135B1 (de) * 1981-09-23 1985-09-11 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Sulfonamid-Potentiator-Lösungen und ein neues Sulfanilamid
JPS59118708A (ja) * 1982-12-27 1984-07-09 Dai Ichi Seiyaku Co Ltd 液状合剤
DE4331147A1 (de) * 1993-09-14 1995-03-16 Nycomed Arzneimittel Gmbh Intravenös verabreichbare, wäßrige Lösung
US5707996A (en) * 1995-11-06 1998-01-13 Macleod Pharmaceuticals, Inc. Pharmaceutical solution and methods for preparation thereof
CA2598668A1 (en) * 2005-02-25 2006-09-08 Mutual Pharmaceutical Company, Inc. Dosage forms of antibiotics and combinations of antibiotics and symptomatic relief agents
ATE542527T1 (de) 2005-05-13 2012-02-15 Topotarget Uk Ltd Pharmazeutische formulierungen von hdac-hemmern

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH247344A (de) * 1945-11-29 1947-02-28 Ciba Geigy Verfahren zur Herstellung eines neuen Kondensationsproduktes des Sulfathiazols.
NL78195C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1946-12-19
NL64566C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1946-12-19
AT174151B (de) * 1949-03-24 1953-03-10 Boehringer & Soehne Gmbh Verfahren zur Hydrophilisierung der Sulfonamide
DE836079C (de) * 1950-09-17 1952-04-07 Inh Apoth E Rath Verfahren zur Herstellung haltbarer Loesungen aus Sulfonamiden und Hexamethylentetramin
DE954725C (de) * 1953-01-21 1956-12-20 Chemie Linz Ag Verfahren zur Herstellung von wasserloeslichen Sulfonamidpraeparaten
GB792449A (en) * 1955-02-21 1958-03-26 Cilag Ltd Condensation products of sulphaguanidine and formaldehyde and their production
US2909522A (en) * 1957-02-21 1959-10-20 Burroughs Wellcome Co Trialkoxybenzylpyrimidines and method
CH544053A (de) * 1966-05-09 1973-11-15 Hoffmann La Roche Verfahren zur Herstellung von Sulfonamidderivaten
US3985876A (en) * 1973-01-05 1976-10-12 Burroughs Wellcome Co. Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine
GB1469521A (en) * 1973-01-05 1977-04-06 Wellcome Found Antimicrobial preparations
DE2731013C2 (de) * 1977-07-08 1982-07-15 Lentia Gmbh Verfahren zur Herstellung einer wäßrigen Infusionslösung

Also Published As

Publication number Publication date
BG35324A3 (en) 1984-03-15
BR8101752A (pt) 1981-09-29
DK94381A (da) 1981-09-26
US4532245A (en) 1985-07-30
EP0037501A1 (de) 1981-10-14
HK78184A (en) 1984-10-26
GB2073587A (en) 1981-10-21
KE3419A (en) 1984-08-10
IS2626A7 (is) 1981-09-26
FI72876C (fi) 1987-08-10
AT374365B (de) 1984-04-10
AU6851381A (en) 1981-10-01
EP0037501B1 (de) 1984-07-18
MW881A1 (en) 1982-06-09
OA06776A (fr) 1982-06-30
CS235086B2 (en) 1985-04-16
IL62432A0 (en) 1981-05-20
ATA137581A (de) 1983-09-15
CA1158158A (en) 1983-12-06
HU185415B (en) 1985-02-28
DK158829C (da) 1990-12-24
GR74453B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-06-28
DE3111067A1 (de) 1982-02-18
ZA811843B (en) 1982-04-28
NO158656C (no) 1988-11-23
IE810657L (en) 1981-09-25
MC1372A1 (fr) 1982-01-19
FR2479211B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-01-13
NL8101152A (nl) 1981-10-16
NO811003L (no) 1981-09-28
PT72727B (en) 1983-01-10
ES8302457A1 (es) 1983-02-01
AR231230A1 (es) 1984-10-31
RO82024B (ro) 1984-07-30
JPS56145224A (en) 1981-11-11
MY8500681A (en) 1985-12-31
FI72876B (fi) 1987-04-30
DD157536A5 (de) 1982-11-17
CH647412A5 (de) 1985-01-31
IL62432A (en) 1984-07-31
AU545277B2 (en) 1985-07-11
KR830004845A (ko) 1983-07-20
RO82024A (ro) 1984-05-23
GB2073587B (en) 1984-02-29
IT1210991B (it) 1989-09-29
MTP884B (en) 1984-06-05
DZ276A1 (fr) 2004-09-13
SG43384G (en) 1985-03-08
NO158656B (no) 1988-07-11
NZ196553A (en) 1983-11-18
IT8119892A0 (it) 1981-02-20
PT72727A (en) 1981-04-01
LU83246A1 (fr) 1983-02-22
ZW4881A1 (en) 1981-10-14
IE51065B1 (en) 1986-09-17
FR2479211A1 (fr) 1981-10-02
PH17972A (en) 1985-02-22
DE3164826D1 (en) 1984-08-23
IN152637B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-02-25
ATE8460T1 (de) 1984-08-15
FI810874L (fi) 1981-09-26
ES500635A0 (es) 1983-02-01
JPH0158166B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-12-11
SE8101884L (sv) 1981-09-26
CU35438A (en) 1983-04-06
DK158829B (da) 1990-07-23

Similar Documents

Publication Publication Date Title
US5082863A (en) Pharmaceutical composition of florfenicol
FI79944B (fi) Oxikam-derivat innehaollande farmaceutiska kompositioner och deras framstaellningsfoerfarande.
JPH0413325B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR840002014B1 (ko) 약학적 제제의 제조방법
KR880001751B1 (ko) 설폰아미드-강화제 용액의 제조방법
JPS605567B2 (ja) オキシテトラサイクリンの調合液
KR100807650B1 (ko) N-[o-(p-피발로일옥시벤젠술포닐아미노)벤조일]글리신·모노나트륨염·4수화물의 동결 건조 제제 및 그 제조 방법
DK159376B (da) Fremgangsmaade til fremstilling af et stabilt, fast, vandoploeseligt praeparat til rekonstituering med vand eller en vandig baerer som en stabil oploesning af 4'-(9-acridinylamino)methan-sulfon-m-anisid
KR100725076B1 (ko) N-[o-(p-피발로일옥시벤젠술포닐아미노)벤조일]글리신·모노나트륨염·4수화물 함유 용액 및 제제
JP2001163776A (ja) 安定化された液剤
CA1073353A (en) Sulphonamide/potentiator solutions
JPS60126217A (ja) 長期徐放性製剤
DK159957B (da) Fremgangsmaade til fremstilling af en til intravenoes indgivelse bestemt vandig oploesning af et sulfonamid sulfonamidpotentiator
HU210693B (en) Process for producing pharmaceutical compositions for injections without tissue damages, containing sulfamethoxazol and trimetoprime
KR19980041046A (ko) 파모티딘의 주사용 액제 및 이의 동결건조 제제

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 11

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19951106

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19951106

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000